Background: Alcohol consumption accelerates the progression and worsens the outcomes of hepatitis C viral (HCV) infection in heavy and moderate drinkers. Our aim was to investigate the effects of two modes of oral ethanol feeding on induction of oxidative stress, impaired methyl...
Open access
Research Article10.9734/IJBCRR/2014/9689
Background: An estimated 2 million children die of malaria yearly, primarily because of Plasmodium falciparum and its complications. Plasmodium falciparum infection could lead to imbalance in micronutrient levels. Micronutrients such as zinc and copper are essential for immune fu...
Open access
Research Article10.9734/IJBCRR/2014/7827
Aims: This study was carried out to investigate the ulcero–protective activity of methanolic extract of Acacia ataxacantha leaves (MEAAL) against indomethacin and stress induced gastric ulcer in experimental rats. Study Design: Administration of MEAAL at the dose of 100mg/kg body...
Open access
Research Article10.9734/IJBCRR/2014/8747
Aim: Comparing cord blood levels of total Creatine kinase (CK) and Creatine kinase MB isoenzyme (CK-MB) in newborns delivered by vaginal delivery and cesarean section. Study Design: Descriptive prospective study. Place and Duration of Study: All neonates delivered from Septemb...
Open access
Research Article10.9734/IJBCRR/2014/8394
Aims: To characterize the serum complement innate immune system in three species of crocodilians native to southeast Mexico. Methodology: Plasma collected from three wild crocodilian species native to southeast Mexico were exposed to sheep red blood cells (SRBCs) to measure hemol...
Open access
Research Article10.9734/IJBCRR/2014/7825
Aims: Extracellular heat shock protein 70 (Hsp70) is an adjuvant molecule that stimulates the immune system. The C-terminal domain of Hsp70 (C70), without the ATPase domain, is sufficient for antigen cross-presentation. However, the mechanism by which the receptor mediates the u...
Open access
Research Article10.9734/IJBCRR/2014/8699
Aims: Despite of intensive investigation of alcoholism consequences for nervous system, the full complex of such metabolic alterations in brain remains unknown. The aim of present work was to study the influence of chronic ethanol consumption on rats’ brain contents of free amino...
Open access
Research Article10.9734/IJBCRR/2014/8809
Periwinkles (Tympanotonus fuscatus) handpicked from the New Calabar River were acclimated to laboratory conditions in the research laboratory of the Chemistry Department of the Ignatius Ajuru University of Education, Rumuolumeni, Port Harcourt. They were subjected to concentratio...
Open access
Research Article10.9734/IJBCRR/2014/8079
Objectives: The aim of the present study was to assess Apolipoprotein B (Apo-B) and Triglyceride/High Density Lipoprotein Cholesterol (TG/HDL-C) ratio as indicators of insulin resistance (IR) with Homeostasis Model of assessment of insulin resistance (HOMA IR)) in metabolic syn...
Open access
Research Article10.9734/IJBCRR/2014/7590
Loop-mediated isothermal amplification (LAMP), a nucleic acid amplification technology, has been characterized as having a short reaction time while generating a large amount of DNA product under isothermal conditions. Here, we found that LAMP is able to amplify more than one tar...
Open access
Research Article10.9734/IJBCRR/2014/7747
The effect of chronic exposure to petroleum hydrocarbon (PHC) pollution on the concentrations of glucose, serum and liver malondialdehyde (MDA), protein carbonyl and the histology of liver tissues of the native fowl (Gallus domesticus) from Egbema in the Niger Delta Area (NDA)...
Open access
Research Article10.9734/IJBCRR/2014/7336
Background: Cowpea, a major source of vegetable protein for millions in Africa is mostly preserved using synthetic chemicals e.g. phosphide. Because a large number of people who carry out grain fumigation are largely untrained, sometimes contamination of fumigated grain with spen...
Open access
Research Article10.9734/IJBCRR/2014/3129
The classic renin-angiotensin system (RAS) is described as a circulating hormone system with primary roles in the regulation of blood pressure, body water balance and thirst and control over vasopressin and aldosterone release. Recently local tissue RASs have been identified with...
Open access
Research Article10.9734/IJBCRR/2014/6569
The effect of sublethal contaminations (100 mg/dm3) of heavy metals such as mercury (Hg), lead (Pb) and cadmium (Cd) on soil enzyme and physicochemical properties was investigated after one hundred and twenty days. Soil sample without heavy metal contamination served as the contr...
Open access
Research Article10.9734/IJBCRR/2014/6341
Aims: Oxidative stress is one of the major pathophysiologic hallmarks in the development of COPD and lung is protected against this by enzymatic and non-enzymatic antioxidants. Total antioxidant activity (TAC), may give more relevant biological information about the individual's...
Open access
Research Article10.9734/IJBCRR/2014/7264