In the G protein-coupled receptors (GPCRs) relatively short regions of their intracellular loops and cytoplasmic C-terminal domain are responsible for specific interaction with G-proteins. GPCR-derived peptides corresponding to these regions are able to influence the activity of...
Open access
Research Article10.9734/IJBCRR/2013/5593
Three proteinaceous pheromone families, the androgen-binding proteins (ABPs), the exocrine-gland secreting peptides (ESPs) and the major urinary proteins (MUPs) are encoded by large gene families in the Mus musculus and Rattus norvegicus genomes. The purpose of this article is to...
Open access
Research Article10.9734/IJBCRR/2013/5763
Aims: To determine the role of human beta defensin-2 and oxidative stress by measuring serum human beta defensin-2 and antioxidant parameters in ovarian cancer patients. Study Design: Serum human beta defensin-2 (HBD-2), and the levels of antioxidants such as serum superoxide dis...
Open access
Research Article10.9734/IJBCRR/2013/5105
Aberrant Jagged1-mediated Notch activation is linked to cancer and induces epithelial-to-mesenchymal transition through the repression of E-cadherin transcription. All three proteins are subject to sequential proteolytic events referred to as regulated intramembrane proteolysis....
Open access
Research Article10.9734/IJBCRR/2013/3847
Purpose: This study was conducted to assess the effect of the ethyl acetate fraction (AcEF1) obtained from the 96% extract of Morinda morindoides extract on cardiac tissue integrity and function in rabbits. Methodology: The rabbits were divided in five groups of 6 rabbits e...
Open access
Research Article10.9734/IJBCRR/2013/4251
Aims: The present paper aims to study the effect of aromatic structure on the inhibition of biogas production and more specifically the effect of para substituted anilines functional groups (chemical structure) on methane biosynthesis by the digested pig manure methanogens. The o...
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Research Article10.9734/IJBCRR/2013/2458
Glutathione S-transferase enzyme (GSTT1 and GSTM1) gene polymorphisms have been associated with the genetic susceptibility to end stage renal disease (ESRD) in different populations. We investigated the association between GSTT1 and GSTM1 genes, and ESRD in Egyptian population. T...
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Research Article10.9734/IJBCRR/2013/4464
Aims: To evaluate anti-diabetic and liver enzymes activities of aqueous extracts of Moringa oleifera and Bridelia ferruginea leaves in alloxan induced diabetic albino rats. Study design: Diabetes was induced in three groups of rats, one group was not treated while two groups were...
Open access
Research Article10.9734/IJBCRR/2013/3859
Osteoporosis is a major health concern that is associated with an increased risk of first and subsequent bone fractures. Untreated osteoporosis results in considerable morbidity. Currently, bisphosphonates are the mainstay of treatment for osteoporosis and the aim of this study w...
Open access
Research Article10.9734/ijbcrr/2013/4210
Aim: To analyze the active sites of various prokaryotic and eukaryotic DNA polymerases and propose a plausible mechanism of action for the polymerases with the Escherichia coli DNA polymerase I as a model system. Study Design: Bioinformatics, Biochemical and X-ray crystallographi...
Open access
Research Article10.9734/IJBCRR/2013/3777
The chemical parameters of glucose syrup produced from five different weight ratios of sorghum malt and sweet potato flour using sorghum malt as a source of enzyme hydrolysis were studied. There were variations in the chemical parameters of the samples as a result of the differen...
Open access
Research Article10.9734/IJBCRR/2013/2247
Aims: The effects of oral administration of aqueous leaf extract of Ocimum gratissimum (OG) on biliary and serum bilirubin, cholesterol and electrolytes in streptozotocin (STZ)-induced diabetic Albino Wistar rats was studied. Methodology: Type 1 Diabetes mellitus was induced in t...
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Research Article10.9734/IJBCRR/2013/4258
Aims: To scientific determine the phytochemical constituents of ethanol extract of B. coriacea (EEBC) powdered seeds and its effects on the serum lipid profile, serum atherogenic index, and lipid peroxidation in the serum of hypercholesterolemic rats. Study Design: Twenty male al...
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Research Article10.9734/IJBCRR/2013/2858
The toxicity of Jatropha curcas seeds emanates mainly from phorbol esters. It is known that the seeds are a valuable source of oil, which can be used to produce biodiesel. The cake generated as a by-product, after oil pressing is a protein-rich potential stock for animal feed. Re...
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Research Article10.9734/IJBCRR/2013/2956
Aims: The purpose of this study is to evaluate the effect of aqueous leaf extract of Moringa oleifera (Moringaceae) on plasma glucose level, total cholesterol level, triglycerides (TG), high-density lipoprotein (HDL) and low-density lipoprotein (LDL) in male albino rats. Study De...
Open access
Research Article10.9734/IJBCRR/2013/3639