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All published articles 1176

Phytochemical Studies, In-vitro Antibacterial Activities and Antioxidant Properties of the Methanolic and Ethyl Acetate Extracts of the Leaves of Anogeissus leiocarpus

Barku Y. A. Victor & Abban Grace · International Journal of Biochemistry Research & Review · 2013

Aims: To conduct a study on the antibacterial activity, phytochemical constituents and antioxidant properties that identify the medicinal potency of medicinal plants on the methanolic and ethyl acetate extracts of the leaves of Anogeissus leiocarpus. Antibacterial activity was de...

Open access Research Article 10.9734/IJBCRR/2013/3349

Toxic Effects of Sub-Chronic Administration of Chloroform Extract of Artemisia maciverae Linn on the Kidney of Swiss Albino Rats

Atawodi Sunday Ene-ojo, Ene Aloy Chinedu & Fatihu Muhammad Yakasai · International Journal of Biochemistry Research & Review · 2013

The nephrotoxic potential of sub-chronic doses of chloroform extract of Artemisia maciverae Linn was studied in male Swiss albino rats. The groups were respectively administered chloroform extract of Artemisia maciverae at 0, 50, 100 and 200 mg/kg b.wt for 60 days and then monito...

Open access Research Article 10.9734/IJBCRR/2013/2062

Comparative Hypolipidaemic Effect of Aqueous Extract of Psidium guajava Leaves and Ascorbic Acid in Male Rats

F. E. Uboh, G. O. Igile, I. E. Okon & P. E. Ebong · International Journal of Biochemistry Research & Review · 2013

Aim: To assess the hypolipidaemic properties of aqueous extract of Psidium guajava leaves (AEPGL) and ascorbic acid (vitC) in male albino Wistar rats. Study Design: Three groups of rats were respectively administered distilled water, 200mg/kg of AEPGL and vitC orally, for thirty...

Open access Research Article 10.9734/IJBCRR/2013/2098

Preliminary Studies on the Expression and Purification of Functionally Active Recombinant Plasmepsin 9 from Plasmodium falciparum

Folasade M. Olajuyigbe · International Journal of Biochemistry Research & Review · 2013

Aim: Plasmepsins, a group of homologous aspartic proteinases are attractive drug targets against malaria. Plasmepsin 9 (PM9) expressed in the blood stage of malaria life cycle with unknown function has been strongly considered as a potential target. However, recombinant expressio...

Open access Research Article 10.9734/IJBCRR/2013/3023

Chronological Primacy of Oxidative-Induced Neuronal Damage in the Pathogenesis of Alzheimer's Disease

Selim F. Estefan, Aziza B. Shalby & Hanaa H. Ahmed · International Journal of Biochemistry Research & Review · 2013

Alzheimer’s disease (AD) is associated with hallmark pathologies including extracellular Aβ protein deposition in extracellular senile plaques and vessels, and intraneuronal tau deposition as neurofibrillary tangles. The current study comprises the oxidative modifications associa...

Open access Research Article 10.9734/IJBCRR/2013/2593

Polyprenols of Grape Vitis vinifera L. Leaves

U. T. Zakirova, N. M. Mamatkulova, Kh. U. Khodjaniyazov, N. K. Khidyrova & Kh. M. Shakhidoyatov · International Journal of Biochemistry Research & Review · 2013

Aims: The study is aimed to isolate of polyprenols from grape Vitis vinifera L. leaves by different methods and to determine of polyprenol content of plant leaves growing in various regions of Uzbekistan. Study Design: Isolation of polyprenols. Place and Duration of Study: Depart...

Open access Research Article 10.9734/IJBCRR/2013/2935

Antifungal Activity of Terminalia mantaly on the in vitro Growth of Cryptococcus neoformans

Ackah Jacques Auguste Alfred Bognan, Yayé Yapi Guillaume, Yapi Houphouet Felix, KRA Adou Koffi Mathieu & Djaman Allico Joseph · International Journal of Biochemistry Research & Review · 2013

Among the HIV / AIDS infected, individuals contract fungal infections of which many die as a direct consequence of these infections. In this study, the antifungal activity of ten extracts (stem bark) from Terminalia mantaly H. Perrier was evaluated on the in vitro growth of clini...

Open access Research Article 10.9734/IJBCRR/2013/2438

Urinary Excretion of Glycosaminoglycans in Patients with Urolithiasis

Seema Jawalekar, Vasant Surve & Anil Bhutey · International Journal of Biochemistry Research & Review · 2013

The interaction between tubular epithelial cells and calcium oxalate crystals or oxalate ions is a very precarious event in the lithogenesis. Urine contains ions, glycoproteins and glycosaminoglycans that inhibit the crystallization process and may protect the kidney against lith...

Open access Research Article 10.9734/IJBCRR/2013/2850

Hormonal Sensitivity of Adenylyl Cyclase in the Myocardium, Brain and Testes of 18-month-old Non-Diabetic and Diabetic Rats

Alexander O. Shpakov, Kira V. Derkach, Irina V. Moyseyuk, Oxana V. Chistyakova & Vera M. Bondareva · International Journal of Biochemistry Research & Review · 2013

The alterations and abnormalities in hormone-sensitive adenylyl cyclase (AC) system occur at early stages of the type 2 diabetes mellitus (T2DM) and at later stages of the disease they are, according to our view, one of the factors causing T2DM complications. To study the changes...

Open access Research Article 10.9734/IJBCRR/2013/2833

Activatory Effect of Germination on Catalytic Capacity of Urease Extracted from Beans Samples (Effect of Germination on the Kinetics of Urease from Beans)

C. Egwim Evans & M. Ogunmolasuyi Adewoyin · International Journal of Biochemistry Research & Review · 2013

Aim: This research work was designed to determine the effect of germination on catalytic capacity of urease extracted from seven beans samples. Study Design: Experimental. Place and Duration: Department of Biochemistry, School of Science and Science Education, Federal University...

Open access Research Article 10.9734/IJBCRR/2013/2639

Biophysical Methods for the Elucidation of the S-Layer Proteins/Metal Interaction

Pablo Mobili, Maria de los Angeles Serradell, Claudine Mayer, Véronique Arluison & Andrea Gomez-Zavaglia · International Journal of Biochemistry Research & Review · 2013

Surface-layers (S-layers) are macromolecular paracrystalline arrays of proteins or glycoproteins that can self-assemble into 2-dimensional semi-permeable meshworks to overlay the cell surface of many bacteria and archaea. They usually assemble into lattices with oblique, square o...

Open access Research Article 10.9734/IJBCRR/2013/2431

Evaluation of Physical and Physicochemical Characteristics of Malpighia emarginata DC from the State of Ceará

Sandra M.L. Santos, Anderson M. De Vasconcelos, Valéria S. Oliveira, Edmar Clemente & José M.C. Costa · International Journal of Biochemistry Research & Review · 2013

The potential of acerola as a natural source of vitamin C is great, as well as its capacity for industrial use. However, this and other characteristics of the fruit can be influenced by factors such as soil type, type of reproduction and pluviometrical index. Thus, the aim of thi...

Open access Research Article 10.9734/IJBCRR/2012/1945

Antioxidant Content and Free Radical Scavenging Activity of Honeys of Apis mellifera of Obudu Cattle Ranch

Chinwe S. Alisi, Okey A. Ojiako, Chidi U. Igwe, Cosmas O. Ujowundu, Ken Anugweje & Gloria N. Okwu · International Journal of Biochemistry Research & Review · 2013

Honey is a naturally sweet and viscous fluid produced by honeybees (Apis mellifera) from the nectar of flowers. Proline, free amino acid, tannins, phenols and flavonoids content were determined in eight samples of Obudu cattle ranch honeys. Antioxidant content (ascorbic acid equi...

Open access Research Article 10.9734/IJBCRR/2012/1581

Chloroquine and Vitamin Combination Effects on P. berghei Induced Oxidative Stress

H. O. T. Iyawe & A. O. Onigbinde · International Journal of Biochemistry Research & Review · 2012

Aim: The effect of chloroquine, folic and ascorbic acid on malaria parasite induced oxidative stress was the focus of this study. The study relevance derives from the need to understand the specific roles of these individual organic acids used in combination with chloroquine. Stu...

Open access Research Article 10.9734/IJBCRR/2012/956