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All published articles 379

Correlates of Systolic Blood Pressure Among Middle-Aged U.S. Adults: A Survey-weighted Regression Analysis of NHANES Data (2017 – 2018)

Gideon Kwame Gargar, Rosingh Amofa-Adarkwa & Alice Mabindo Tidola Inyan · International Blood Research & Reviews · 2026

Background: Hypertension is a leading modifiable risk factor for cardiovascular disease, and midlife is a critical period when adverse systolic blood pressure (SBP) trajectories emerge. We estimated nationally representative associations between SBP and demographic, socioeconomic...

Open access Research Article 10.9734/ibrr/2026/v17i3386

Haemorheological Reference Intervals in Sub-Saharan African Populations: A Critical Appraisal of Methodological Standardisation, Ethnic Variability, and Clinical Application

Adenuga Jacob Olaitan, Olusegun Taiwo Oke, Muhibi Musa Abidemi, Adesina Beatrice Ebun, Olatunji Oluwatobi, Ajao Oluwadare Amos & M. B. Ajayi · International Blood Research & Reviews · 2026

Reference intervals, the statistically defined ranges of physiological parameter values expected in a healthy reference population, constitute a cornerstone of clinical laboratory medicine. In haemorheology, reference intervals for whole blood viscosity, plasma viscosity, erythro...

Open access Research Article 10.9734/ibrr/2026/v17i3387

RhD Frequency and Maternal Alloimmunisation Among Pregnant Women Attending Federal Medical Centre, Asaba, Nigeria: Implications for Preventing Foetal and Newborn Haemolytic Disease

Kevin Erhamwonyia Aghatise, Olagboye Josephine Abhankonfoh & David Osayomwanbo Aiyanyor · International Blood Research & Reviews · 2026

Background: Maternal alloimmunisation against the RhD antigen remains a preventable cause of haemolytic disease of the foetus and newborn (HDFN), a condition responsible for substantial perinatal morbidity and mortality in resource-limited settings. Population-specific data on Rh...

Open access Research Article 10.9734/ibrr/2026/v17i3384

Frequency and Distribution of Kell and Duffy Antigens among Blood Donors in Rivers State, Nigeria

Wifa, Yirakpoa Celestine, Christian, Serekara Gideon & Koate, Baribefe Daniel · International Blood Research & Reviews · 2026

Blood group antigen variability has significant implications for transfusion safety and prevention of alloimmunization, particularly in multi-ethnic populations where antigen expression may differ. This study investigated the distribution of Kell and Duffy blood group antigens am...

Open access Research Article 10.9734/ibrr/2026/v17i2383

Access, Adherence and Patient-Reported Outcomes of Hydroxyurea Therapy in Sickle Cell Disease: A Cross-Sectional Study from Nigeria

Kaladada Ibitrokoemi Korubo, Emmanuel Wobo & Uchechukwu Prince Okite · International Blood Research & Reviews · 2026

Background: Hydroxyurea is the most accessible disease-modifying therapy for sickle cell disease (SCD), but in many low- and middle-income countries its real-world benefit is constrained by gaps in awareness, uptake, continuity, and adherence. We analyzed the full hydroxyurea pat...

Open access Research Article 10.9734/ibrr/2026/v17i2382

Evaluation of the Levels of Some Haemostatic Parameters in Women with Uterine Fibroid in Port Harcourt, Nigeria

Onengiye Livingstone Davies, Beauty E. Echonwere-Uwikor, Beatrice W. Moore-Igwe & Stella U. Ken-Ezihuo · International Blood Research & Reviews · 2026

Uterine fibroid is a common gynaecological condition that affects the health of women globally. This cross-sectional study evaluated the levels of some haemostatic parameters in women with uterine fibroid. The study involved 240 subjects who were within the ages of 20 and 45 year...

Open access Research Article 10.9734/ibrr/2026/v17i2381

Evaluation of Clinical Utility and Sample Types for Emerging Specific and Direct Alcohol Biomarkers for the Detection of Alcohol Use History among Prospective Blood Donors: A Theoretical Review

Jacques Forwah Ndeh, Ushie Godwin Abua, Edung Emem Samuel, Ogochukwu Chinwoke Etoniru, Chukuamaka Iweze Ifukor, Chiamaka Vianney Ndimele, Edung Catherine, Worship Tega Ewhrudjakpor, Akpojovwo Esther Ufuomanefe, Chinedum Sam Iheukwumere, Aishatu Omoragbon, Abayomi Oluwatobi Opadijo, Felix Nsofor, Ibuje Taghogho Emuobo, Amahan Anne, Kelechi Chukwuemeka Nwaozuzu, Ekwueme Michael Chibueze, Kunna Ugaliegbulam, Chuba Ifedigbo, Edeani Bobby David, Ewa Anthony Obi, Etukemo Ubong Amos, Idiege Idiege Omang, Ofonime Benjamin Essien, Ngha James Ngah, Ofor Joshua Obase-Otumoyi, Immaculate Ihuoma Ekeagba, Akpojivi Bridget Ejiroghene, Joel Danladi Bala & Abeshi Sylvester Etenikang · International Blood Research & Reviews · 2026

The detection of alcohol use history amongst potential blood donors is crucial to ensure the safety of the blood supply. Traditional laboratory-based testing methods have shown to have some limitations namely lengthy turnaround times and high costs. Emerging direct and specific a...

Open access Research Article 10.9734/ibrr/2026/v17i2380

Evaluation of Integrated Patient-Centered Model of Territorial Transfusion Medicine across Healthcare Settings: A Retrospective Study

Gianluca Gessoni, Giulia de Fusco, Giovanni Roveroni, Carla Rossi, Gabriella Mazzaro, Lauretta Moro, Gianni Tidore, Marta Siviero, Giovanni Carretta, Domenico Bagnara, Raffaella Berti & Silvia da Ros · International Blood Research & Reviews · 2026

Background: In contemporary healthcare systems, the sustainability of complex care models increasingly depends on the transition toward decentralized frameworks. Community-based transfusion therapy have emerged as a strategic approach to ensure continuity of care for frail and ch...

Open access Research Article 10.9734/ibrr/2026/v17i2379

Total and Differential White Blood Cell Counts among Women with Dysmenorrhea in a Tertiary Institution in Nigeria

Eledo, Benjamin Onyema & Chinedu-Madu Jane Ugochi · International Blood Research & Reviews · 2026

Dysmenorrhea is a common gynecological condition marked by recurrent menstrual pain, predominantly affecting females of reproductive age. The immune system is intricately connected to menstrual cycle regulation, and various endogenous and exogenous factors can alter the leukocyte...

Open access Research Article 10.9734/ibrr/2026/v17i1378

P-selectin Marker in Venous Thromboembolism

Jumala Nikhitha, Amulya Kalidindi, Sandeep Kumar Tipparthi, RajKumar HRV & Guru Prasad Manderwad · International Blood Research & Reviews · 2026

Venous thrombosis is a life threatening disease associated with high morbidity and mortality. Predisposing factors of venous thrombosis associated with obesity, age, varicose veins etc. There is an interaction between the thrombosis and inflammation. P selectin unregulated glycop...

Open access Research Article 10.9734/ibrr/2026/v17i1377

Disseminated Intravascular Coagulation (DIC) Following Acute Hemolytic Transfusion Reaction (AHTR) in a Pregnant Woman in Rural Tanzania: A Case Report

Abdu Hussein Mogella, Omary Shaban Kilume, Witness Lubomba, Gabriel Yessaya Nalaila, Martin Rohacek, Zenais Augustino Mselle, Theresia Karuhanga, Issa Shabani Nyangala, Elias Kweyamba & Emmanuel Chogo · International Blood Research & Reviews · 2026

Background: Acute Hemolytic Transfusion Reaction (AHTR) is a severe transfusion-related complication that may precipitate secondary DIC. This risk is higher in pregnant women, where physiological hypercoagulability can mask early signs. Case Presentation: We report a 23-year-old...

Open access Research Article 10.9734/ibrr/2026/v17i1376

Premarital Screening for Haemoglobin Genotype, HIV and Syphilis among Prospective Couples in Port Harcourt, Nigeria

Chidi L. C. Ndukwu · International Blood Research & Reviews · 2026

Background: Premarital medical screenings for prospective marital couples are vital public health tools for the prevention of such hereditary diseases as sickle cell disease, sexually transmitted and bloodborne infections, which may be transmitted from one spouse to the other and...

Open access Research Article 10.9734/ibrr/2026/v17i1375

Epidemiology and Risk Stratification of Microcytic Hypochromic Anemia in Pregnancy: A Cross-sectional Study in Takoradi, Ghana

Ransford Oduro Kumi, Emmanuel Ayitey, Rita Ofosuaa Agyemang Ntim, Sefakor Adzo Agbenyegah, Andrews Kumi, Belinda Oti & Isaac Kporha · International Blood Research & Reviews · 2026

Anemia in pregnancy is a major public health concern, particularly in low-resource settings, where iron deficiency remains the leading cause. This study investigated the prevalence, determinants, and risk profiling of microcytic hypochromic anemia, a type of anemia characterized...

Open access Research Article 10.9734/ibrr/2026/v17i1374

Mapping Delays in Diagnosing Haematologic Malignancies in Adults in Rivers State, Nigeria: Perspectives from Patients and Healthcare Providers

Paxman Dandyson Uku, Christine Abaiayam Dangana, Emmanuel Wobo, Amarachi Faith Mbonu, Doreen Obugheni Arugu, Linda Anucha Dublin-Greene, Anuale Bright Piakorn, Thankgod Chukwudinma Bethel & Chimankpam Edison Okechukwu Omeodu · International Blood Research & Reviews · 2025

Introduction: In developing countries, patients tend to present late to healthcare facilities and this makes early diagnosis impossible. The experience among patients with haematologic malignancies in our part of the world is not different. The objective of this survey was to ide...

Open access Research Article 10.9734/ibrr/2025/v16i4373

Brentuximab Vedotin and Bendamustine Protocol in Hodgkin Lymphoma: Report of Two Cases in Abidjan, Côte d'Ivoire

Boidy Kouakou, Edgard Julien Sonkwa Lontsi, Yao Nicaise Atiméré, Alexis Dohoma Silué, Ismael Kamara, Danho Clotaire Nanho, Ruth Djeket, Emeraude Ndathz-Comoé, Daouda Koné, Norman Isaac Klebair Kouamé, Emmanuela Hiabba Assohou-Koffi & Gustave Kouassi Koffi · International Blood Research & Reviews · 2025

Background: Hodgkin lymphoma is the first hematology malignancy to be cured. The Management of mediastinal or pulmonary location, whether inaugural or secondary, is restricted with conventional chemotherapy which contains cardio- or pneumotoxic molecules. The new Advanced therape...

Open access Research Article 10.9734/ibrr/2025/v16i4372