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All published articles 883

Effects of Light at Night and Methamphetamine on Reproductive Hormones, Estrous Cycle and Histology of the Reproductive Organs in Female Albino Wistar Rats

Makuachukwu Francisca Chinweokwu Mgbemena & Ed. Nwobodo · Journal of Advances in Medical and Pharmaceutical Sciences · 2026

Background and Aim: Light at night (LAN) and methamphetamine (Meth) are emerging environmental and pharmacological stressors implicated in neuroendocrine and reproductive dysfunction. This study investigated the independent and combined effects of LAN and Meth on reproductive hor...

Open access Research Article 10.9734/jamps/2026/v28i6863

Rethinking Nanoparticle Therapeutics: Phytochemical Self-aggregation as a Hidden Driver of Biological Performance

Salaheldin Elabiad & Nazmi Özer · Journal of Advances in Medical and Pharmaceutical Sciences · 2026

Natural products remain a cornerstone of drug discovery, providing structurally diverse bioactive compounds with significant therapeutic potential. Their incorporation into nanomedicine, either as active pharmaceutical ingredients or functional excipients, has expanded rapidly du...

Open access Research Article 10.9734/jamps/2026/v28i6864

Atopic Dermatitis among Children in Bamenda II, Cameroon: Prevalence and In-vivo Therapeutic Effects of Aqueous Extract of Cassia alata against DNCB Induced Atopic Dermatitis in Rats

Habiba Zaitune, Che Lemnwui Gwendoline, Oumar Mahamat & Tume Christopher · Journal of Advances in Medical and Pharmaceutical Sciences · 2026

Atopic dermatitis (AD) is a common inflammatory skin disease affecting populations worldwide, with various treatment approaches. This study aimed to determine the prevalence of atopic dermatitis among children in Bamenda II subdivision and to evaluate the biological activities su...

Open access Research Article 10.9734/jamps/2026/v28i5861

Microplastics as a Modulator of Oncogenic Gene Expression and Oxidative Stress in Glioblastoma Cancer

Md. Mohiuddin Rahaman Rakib, Shadia Shamim, Abu Jubaer Asif, Raisa Islam, Moushumi Kabir Anisa, Mamun Or Rashid, Anandy Islam & Tanvir Kabir · Journal of Advances in Medical and Pharmaceutical Sciences · 2026

Glioblastoma represents the most aggressive form of primary brain tumor and continues to exhibit significant resistance to standard treatment approaches. Emerging environmental contaminants, such as microplastics, have demonstrated the ability to induce oxidative stress and cellu...

Open access Research Article 10.9734/jamps/2026/v28i5862

Posterior Uveitis with Serous Retinal Detachment as a Severe Extra-Articular Manifestation of Psoriatic Arthritis: A Case Report

Soukaina Mounsif, Mina Moudatir, Khadija Echchilali, Meriem Benzakour & Hassan El Kabli · Journal of Advances in Medical and Pharmaceutical Sciences · 2026

Background: Psoriatic arthritis (PsA) is a chronic immune-mediated inflammatory disease that may be associated with extra-articular manifestations, including uveitis. Ocular involvement is uncommon in PsA and usually limited to anterior uveitis. Posterior uveitis complicated by s...

Open access Research Article 10.9734/jamps/2026/v28i5860

Antioxidant and Antibacterial Activities of Aqueous and Hydroethanolic Extracts from the Pericarp of Garcinia mangostana L.

Jaures Arnaud Noumedem Kenfack, Liliane Foutse Yimta, Doriane Esther Djeussi, Viviane Tala Sipowo, Synthia Kenne-D, Aimé Gabriel Fankam, Landry Fotsing Silatsa & Pierre Michel Jazet Dongmo · Journal of Advances in Medical and Pharmaceutical Sciences · 2026

Background: Oxidative stress and antibiotic-resistant bacterial infections pose major global health challenges, increasing interest in plant-based alternatives. Garcinia mangostana is traditionally used for its bioactive compounds with potential antioxidant and antibacterial prop...

Open access Research Article 10.9734/jamps/2026/v28i5859

Factors Influencing the Uptake of Family Planning Services among Women Attending Antenatal Clinic at Major Health Facilities in Zaria, Nigeria

Ushakuma Michael Anenga, Lucia Oluwayomi Ale, Amina Abdulkarim & Rabiatu Aminu Saleh · Journal of Advances in Medical and Pharmaceutical Sciences · 2026

Background: Family planning is a key component of reproductive health, yet uptake remains suboptimal in Northern Nigeria despite high awareness among women of reproductive age. Women attending antenatal clinics therefore, represent an important target group for family planning in...

Open access Research Article 10.9734/jamps/2026/v28i4857

Recent Advances and Mechanistic Insights into Hydrotropic Solubilization: From Conventional Agents to Novel Combination Strategies

G. W. Ugodi & E. C. Ezeamah · Journal of Advances in Medical and Pharmaceutical Sciences · 2026

The poor aqueous solubility of emerging drug candidates remains a formidable challenge in pharmaceutical development, directly limiting oral bioavailability and therapeutic efficacy. Hydrotropic solubilization has gained significant attention as a versatile, cost-effective, and e...

Open access Research Article 10.9734/jamps/2026/v28i5858

Artificial Intelligence-Driven Drug Discovery: Transforming the Pharmaceutical Pipeline from Target Identification to Clinical Translation

Nazmi Özer & Al Hareth Al Obeidan · Journal of Advances in Medical and Pharmaceutical Sciences · 2026

The pharmaceutical industry faces profound challenges in its quest to develop novel, safe, and efficacious therapeutics. Traditional drug discovery pipelines are characterised by astronomical costs, protracted timelines, and high attrition rates, with the average cost of bringing...

Open access Research Article 10.9734/jamps/2026/v28i4856

Pattern of Hydrocephalus among Children in a Tertiary Hospital in Port Harcourt, Nigeria

N. Gabriel-Job, A.I Frank-Briggs & S. I. Douglas · Journal of Advances in Medical and Pharmaceutical Sciences · 2026

Introduction: Paediatric hydrocephalus is gradually becoming an emerging public health problem in Africa including Nigeria, largely because of the challenges patients face in accessing comprehensive healthcare, with delayed hospital presentation being predominantly common. This r...

Open access Research Article 10.9734/jamps/2026/v28i4855

Phytotherapeutic Potential of Azadirachta indica: Modulating SARS-CoV-2 Viral Entry and the Endothelial Pro-inflammatory Cascade

Rupam Debnath, Ayan Sarkar, Mahuya Singha, Tej Narayan Kumar & Sukanta Debnath · Journal of Advances in Medical and Pharmaceutical Sciences · 2026

Azadirachta indica (neem) is a versatile medicinal plant with potent antiviral, anti-inflammatory, and immunomodulatory properties. This study evaluates its phytotherapeutic potential in modulating SARS-CoV-2 entry and the subsequent pro-inflammatory cascade. Bioactive constituen...

Open access Research Article 10.9734/jamps/2026/v28i4853

A Retrospective Assessment of Clinical Risk Factors Associated with Pulmonary Embolism

Ibikunle Moses Durotoluwa & Ezinne Ijeoma Madubuonu · Journal of Advances in Medical and Pharmaceutical Sciences · 2026

Background: Pulmonary embolism (PE) is a serious and potentially life-threatening cardiovascular condition, significantly contributing to global morbidity and mortality. Despite increasing recognition in sub-Saharan Africa, particularly in Nigeria, limited context-specific data o...

Open access Research Article 10.9734/jamps/2026/v28i4854

Comparative Analysis of Microbial Load and Public Health Implications of Factory-Processed and Locally Prepared Foods in Port Harcourt, Nigeria

Lynda Kadi, Giami & G.C Disegha · Journal of Advances in Medical and Pharmaceutical Sciences · 2026

Foodborne microbial contamination remains a major public health challenge in low- and middle-income countries, where both factory-processed and locally prepared foods contribute significantly to daily dietary intake. This study evaluated the microbial population, diversity, and p...

Open access Research Article 10.9734/jamps/2026/v28i3852

Medication Non-adherence in Schizophrenia and Bipolar Affective Disorder: A Cross-sectional Study from Two Tertiary Hospitals in South-South Nigeria

Jombo, Henry Effiong, Abasiubong Festus Udo Bassey, Abiama Emmanuel Ekpedoho, Ubi Idongesit Ayemo, Ogundipe Seyi Sunday & Idiong Ekerete Udoobot · Journal of Advances in Medical and Pharmaceutical Sciences · 2026

Background: Symptoms remission and significant improvements in functionality is predicated on good medication adherence. Non-adherence to medication in persons with bipolar disorder and schizophrenia is the main reason for frequent relapses and poor treatment outcomes. Aims: This...

Open access Research Article 10.9734/jamps/2026/v28i3851

Translational Insight into Gongronema latifolium-silver Nanoparticles: Linking in vivo Safety to Molecular Antimalarial Mechanism

Goodnews Onyedikachi Ikeh, Jasmine Kayanian, Nkoyo Imelda Nubila, Charles C. Diovu, Sunday Kaura, Ndidiamaka H. Okorie & Ibeabuchi J. Ali · Journal of Advances in Medical and Pharmaceutical Sciences · 2026

Building upon our recent finding that the biopolymer matrix of green-synthesized silver nanoparticles (AgNPs) dictates their exceptional safety (LD50 > 5000 mg/kg) and antimalarial efficacy, this study employed a computational framework to de-convolute the molecular identity o...

Open access Research Article 10.9734/jamps/2026/v28i3850