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All published articles 883

In-vivo Anti-typhoid Activities of Ethanol Stem Bark Extract of Bridelia ferruginea (Wild) in Albino Rats Infected with Salmonella typhi

Ebenezer Oluyemi Dada & Busayo Temitope Akinyele · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Aims: To study the In-vivo anti-typhoid activities of ethanol stem bark extract of Bridelia ferruginea in albino rats infected with Salmonella typhi. Study Design: Experimental design. Place and Duration of Study: Department of Microbiology, Federal University of Technology, Akur...

Open access Research Article 10.9734/jamps/2020/v22i530170

Homocysteinaemia in Heart Failure Patients in North Eastern Nigeria

Y. A. Ayoola, H. I. Okolie, O. M. Akinlade, O. G. Oluwatoyin, M. W. Ali & S. A. Biliaminu · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Aims: The study was aimed at determining the relationship between plasma homocysteine level and indices of severity in heart failure patients seen at a referral teaching hospital in Gombe, Northeast Nigeria. Study Design: It was a hospital based cross-sectional study conducted on...

Open access Research Article 10.9734/jamps/2020/v22i430168

Anaemia, Body Mass Index and Risk Factors Association with Malarious Pregnant Women in Ebonyi State, Nigeria

C. A. Imakwu, J. C. Ozougwu, O. P. Okeke, G. U. Amana & S. C. Eziuzor · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Aims: Malaria in pregnancy is a weighty health problem in sub-Saharan Africa where 90% of the global malaria burden occurs, therefore there is urgent need for more researches on malaria in pregnancy to reduce its mortality and morbidity. Anaemia, body mass index and risk factors...

Open access Research Article 10.9734/jamps/2020/v22i430167

Pharmacological Investigation of Serial Anxiety Tests in the Mouse: A Pilot Study

A. M. Umarudeen, M. G. Magaji, O. S. Bello, C. Aminu & M. I. Abdullahi · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

The use of test batteries has been suggested as a means to enhance throughput, to broaden the spectrum of anxiety parameters detectable and to minimise the numbers of experimental animals required in behavioural studies. This study was undertaken to determine the sensitivity of t...

Open access Research Article 10.9734/jamps/2020/v22i430166

Prophylactic and Therapeutic Effect of Aqueous Stem Extract of Costus afer on Lipids and Atherogenic Profile of Albino Rats in Acetaminophen Induced Liver Toxicity

L. L. Nwisah, T - E. G. Davies & E. S. Bartimaeus · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Background: Medicinal plants are widely used in Nigeria because they are believed to be effective in the treatment of various medical conditions and are also easily accessable with minimal side effect. Aim: This study evaluates the prophylactic and therapeutic effects of differen...

Open access Research Article 10.9734/jamps/2020/v22i430165

The Impact of Intervention on Pharmacists’ Counselling on Patients’ Knowledge and Opinion of Antibacterial Usage

Adeola Adebisi Michael, Omole Moses Kayode & Itiola Oludele Adelanwa · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

The knowledge and opinion of patients on antibacterial usage depends on pharmacist’s counselling. In Nigeria, study assessing patients’ perception of pharmacists’ antibacterial counselling is scarce. This study assessed the knowledge and opinion of patients on antibacterial usage...

Open access Research Article 10.9734/jamps/2020/v22i430164

Short Term Toxicological Evaluation of the Pentaclethra macrophylla (Benth) Essential Oil (Oil Bean Seed) on Organs of Normal Male Albino Rats

A. M. Yusuf-Babatunde, L. S. Kasim & O. T. Osuntokun · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

The purpose of this research is to evaluate the short term toxicological assessment of the Pentaclethra macrophylla (Benth) oil (oil bean seed) on organs of normal male albino rats. Fresh pods of Pentaclethra macrophylla (Benth) were collected directly from the plant tree in July...

Open access Research Article 10.9734/jamps/2020/v22i330163

Medical Students and Internet Addiction: A Study at Bolan University of Medical and Health Sciences Quetta, Pakistan

Zulfiqar Khosa, M. Yaseen Bazai, Abdullah Zulfiqar Khosa & Hamaiyal Sana · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Objective: The use of internet is unavoidable in daily life. The young individuals are more prone to this condition. Beside many good benefits certain hazards are indicative richly observed in adolescent. The addiction test for internet usage is largely popular by using Internet...

Open access Research Article 10.9734/jamps/2020/v22i330162

Assessment of Inflammatory and Cardiac Status of Echis ocellatus Snake-bite Victims in Jos Metropolis, Plateau State, Nigeria

P. O. Manafa, G. C. Jackson Njoku, C. C. Onyenekwe, O. Ekuma-Okereke, E. E. Nnadi, R. S. Ebugosi, G. O. Chukwuma, E. C. Onah, R. C. Chukwuanukwu, K. E. Nwene, V. I. Manafa & O. S. Ogbuowelu · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Background: This study was designed to evaluate the inflammatory and cardiac status of snakebite victims using serum levels of C-reactive protein (CRP), troponin-I (TnI), total cholesterol (TC) and triglycerides (TG) as markers in Echis ocellatus snakebite victims before and afte...

Open access Research Article 10.9734/jamps/2020/v22i330161

Phytochemistry and Toxicity of Methanol Root Extract of Costus lucanusianus

Hope Delesi Kagbo & Lilian Ayagogo Gospel · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Costus lucanusianus (ginger lily or monkey sugarcane) is a medicinal plant commonly used to treat various ailments in tropical Africa. The leaves, stem and sometimes the root have been exploited for this purpose. However, it is a common belief in the Niger Delta of Nigeria that t...

Open access Research Article 10.9734/jamps/2020/v22i330160

Effect of Caffeine at Different Concentrations on Behavior and Motor Activity in Mice

Sakina S. Saadawi, Khairi A. Alennabi, Sumaya Baayo, Amera Fares, Najwa Alosta & Suher M. Aburawi · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Aims: This article aimed to study the effect of different caffeine concentrations on behaviour and motor activity of mice. Place and Duration of Study: This study took place in Faculty of Pharmacy, University of Tripoli, and was conducted between 2017 to 2018. Methodology: The ex...

Open access Research Article 10.9734/jamps/2020/v22i330159

Highly Active Antiretroviral Therapy Depletes Some Antioxidant Parameters and Increases Free Radical Generation in Drosophila melanogaster

Walter Mdekera Iorjiim, Simeon Omale, Great David Bagu, Steven Samuel Gyang, Emmanuel Taiwo Alemika & Monday Alexander Etuh · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Objective: This study intended to evaluate the toxic effects of Efavirenz-based highly active antiretroviral therapy (EFVb-HAART) on some antioxidant parameters, and free radical generation in D. melanogaster. Materials and Methods: The study was carried out at the Centre of Exce...

Open access Research Article 10.9734/jamps/2020/v22i230158

Illness Perception is a Predictor of Medication Adherence and Health Related Quality of Life in Patients Living with Epilepsy

Unyime Eshiet, Bertha Ekeh & Sidney Oparah · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Objective: To determine the relationship between illness perception, medication adherence and health related quality of life in patients living with epilepsy. Design: A cross-sectional prospective survey among patients living with epilepsy recruited from two tertiary referral cen...

Open access Research Article 10.9734/jamps/2020/v22i230157

Susceptibility Patterns of Some Enteric Bacteria to Crude and Purified Bark Extracts of Annona muricata L.

Ebenezer Oluyemi Dada & Kehinde Yemisi Akinde · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Aims: This research was carried out to evaluate the susceptibility pattern of some enteric bacteria to crude and purified extracts of Annona muricata bark. Study Design: Experimental design. Place and Duration of Study: Department of Microbiology, Federal University of Technology...

Open access Research Article 10.9734/jamps/2020/v22i230156

Formulation and Physicochemical Characterization of Buccal Mucoadhesive Films Containing Alfuzocin Hydrochloride

Abikesh P. K. Mahapatra, Sonia P. Nagvenkar & Rajashree Gude · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

The buccal region of oral cavity is a interesting target for the drug of choice administration. To increase prevent first pass metabolism and bioavailability, Alfuzocin Hydrochloride is embedded in buccal film for a sustained release over a period of 8 hours. The purpose of this...

Open access Research Article 10.9734/jamps/2020/v22i230155