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All published articles 883

Opposite Effects of F1 and F5 Fractions of Total Methanol Leaf-extract of Dialium guineense (Cesalpiniaceae) on Blood Glucose in Rat

Firmin Sylva Barboza, Madièye Sene, Dominique Doupa, Malick Ba, Alassane Wélé & Sy Guata Yoro · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

The purpose of this study is to investigate the effects of total methanol leaf-extract of Dialium guineense (Cesalpiniaceae) and its fractions on blood glucose in rat. The fractions of methanol extract were obtained by chromatography Sephadex LH 20 gel, numbered F1 to F5. Experim...

Open access Research Article 10.9734/jamps/2020/v22i230154

Investigation of the Levels of Total Aflatoxin in Herbal Traditional Medicines from Selected Vendors Dealers in South-Eastern Nigeria

Richard C. Ikeagwulonu, Chinedum C. Onyenekwe, Ifeanyi O. Oshim, Nkechi A. Olise, Oluwayemisi Odeyemi & Chiedozie K. Ojidei · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Aim: To investigate the levels of total aflatoxin (AF) in herbal medicines from selected vendors in South- Eastern Nigeria. Study Design: This is a cross-sectional study designed to investigate the levels of aflatoxin (AF) mycotoxin in herbal traditional medicines selected random...

Open access Research Article 10.9734/jamps/2020/v22i130152

Socio-Demographic and Clinical Profiles of Cannabis Abusers Admitted for Treatment in a Tertiary Healthcare Facility in Uyo, South-South Nigeria

Jombo, Henry Effiong, Alphonsus Udo Idung & Victory Edet Iyanam · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Background: Cannabis is one of the commonly abused psychoactive substances worldwide. The increasing abuse of this psychoactive substance is recognized as a significant public health problem in many developing countries. A proper assessment of the patterns and trends of cannabis...

Open access Research Article 10.9734/jamps/2020/v22i130153

Evaluation of Antihyperlipidaemic Activities of Hydromethanolic Extracts of Dioscorea bulbifera

Bruno Chukwuemeka Chinko, Datonye Victor Dapper & Olaghaguo Maestephen Adienbo · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Introduction: Hyperlipidemia is a leading cause of cardiovascular diseases (CHDs) with treatment ranging from dietary management and the use of antihyperlipidaemic drugs. The desire for anti-hyperlipidaemic drugs with less side effects has led to the screening of medical with ant...

Open access Research Article 10.9734/jamps/2020/v22i130151

Lipidaemic and Hepatic Status of Type 2 Diabetic Rats Treated with the Polyherbal Capsule Glucoblock

O. N. Briggs, K. N. Elechi-Amadi, F. C. Ezeiruaku & R. E. Teme · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

The scourge of diabetes has led to an increase in the use of complementary and alternative medicine. The lack of regulation and control leads to the indiscriminate use of these herbals, with potential risk to patients. Aim: This study evaluates the lipidaemic and hepatic status o...

Open access Research Article 10.9734/jamps/2020/v22i130150

Evaluation of the Levels of Ochratoxin A and Fumonisin B1 Mycotoxins in Herbal Traditional Medicines Selected from Vendor Dealers in Ebonyi State of Nigeria

Richard C. Ikeagwulonu, Charles C. Onyenekwe, Ifeanyi O. Oshim, Zeal C. Ikeagwulonu, Chiedozie K. Ojide & Nkechi A. Olise · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Aim: To determine the concentration of Ochratoxin A and Fumonisin B1 mycotoxins in herbal medications available in markets in Ebonyi State. Study Design: This is a cross-sectional study designed to determine the levels of Ochratoxin A and Fumonisin B1 mycotoxins in herbal traditi...

Open access Research Article 10.9734/jamps/2020/v22i130149

Aromatic Hydrazide Compounds That Inhibit the Growth of Mycobacterium tuberculosis

Ronald Bartzatt, Preeti Sule, Thushara Galbadage & Jeffrey D. Cirillo · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Aims: To demonstrate the efficacy of aromatic hydrazide compounds to inhibit growth of Mycobacterium tuberculosis. Study Design: To synthesize tuberculostats and test their antibacterial activity in-vitro. Place and Duration of Study: University of Nebraska, Durham Science Center...

Open access Research Article 10.9734/jamps/2019/v21i430148

Developement and Characterization of Floating Tablets of Nizatidine for Peptic Ulcer

Sunil T. Galatage, Suresh G. Killedar, Rushikesh B. Katakar, Ravindra B. Kumbhar, Maya Sharma & Pramodkumar J. Shirote · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

The objective of the present research work is to develop an ideal floating drug delivery system of nizatidine to increase the gastric residence time in stomach. To overcome the short half life and lower bioavailability of drug in tablet form we developed the drug in the form of e...

Open access Research Article 10.9734/jamps/2019/v21i430146

Therapeutic Effect of Ethanol Extract of Anthocleista vogelii Stem Bark in the Treatment of Jaundice on Paracetamol-induced Hepatotoxicity in Adult Wistar Rats

B. A. Olatunji & C. U. Ogunka-Nnoka · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

This study investigated therapeutic effect of ethanol extract of Anthocleista vogelii stem bark (EEAV) in the treatment of jaundice on paracetamol-induced hepatotoxicity in adult wistar rats. A total of 30 wistar rats weighing between 160-200 g were distributed into 6 groups comp...

Open access Research Article 10.9734/jamps/2019/v21i430145

Case Series: Management of Foot Drop

Isaac Olusayo Amole, Stephen Adesope Adesina, Adewumi Ojeniyi Durodola & Samuel Uwale Eyesan · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

Aim: To highlight the functional outcome of surgical management of foot drop in patients with Hansen disease. Case Presentation:  We present three cases of foot drop following Hansen’s disease that were managed surgically by Tibialis posterior transfer. The patients had preoperat...

Open access Research Article 10.9734/jamps/2019/v21i430143

Formulation Development and Evaluation of Fast Dissolving Oral Films of Alprazolam

Riffat Latif & Muhammad Ashfaq · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

Fast dissolving oral films provide convenient, safe and simple way of drug administration. Moreover they offer improved patient compliance due to straightforward and non-invasive nature. The aim of current research was to develop fast dissolving oral films of alprazolam for treat...

Open access Research Article 10.9734/jamps/2019/v21i430142

The Immuno-modulatory and Thrombocytopaenic Effects of the Varying Concentrations of the Aqueous Leaf Extract of Moringa Oleifera in Male Albino Wistar Rats

Ojeka Sunday Ogbu & Zabbey Victor Zigabelbari · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

Introduction: Moringa oleifera and related species are commonly used in folk medicine for various human diseases. Aim: The study was undertaken to establish the thrombocytopenic effect of the aqueous leaf extract of moringa oleifera and to find the utilization of platelet paramet...

Open access Research Article 10.9734/jamps/2019/v21i430141

Antimicrobial Activity of Methanolic, Aqueous and Partially Purified Protein of Young and Matured Leaves of Guiera senegalensis (Moshi Medicine)

M. K. Jiyil, C. E. Mafuyai, M. I. Shago & H. M. Inuwa · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

Background: Microorganisms have evolved defence mechanisms against antimicrobial agents and have become resistant to some antibiotics. Aim of the Study: This study aimed to evaluate the antimicrobial activity of methanol as well as that of the aqueous and partially purified prote...

Open access Research Article 10.9734/jamps/2019/v21i430140

Cephalometric Analysis of Sella Turcica for Age Determination from Sokoto, Nigeria: A Radiological Study

Z. Usman, G. H. Yunusa, A. Bello, J. D. Usman, A. Aliu, S. S. Bello, I. M. Ahmad, M. A. Musa, T. Ammani, G. B. Marwan, R. Bello, A. M. Ahmed, U. Abubakar, B. O. Onimisi, H. A. Bunza & A. D. Zagga · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

Cephalometry deals with the measurement of the head or radiological specimen of the head. Sella turcica is an important anatomical structure located in the middle cranial fossa, housing the pituitary gland. Various shapes and sizes of the sellae turcica have been reported. Howeve...

Open access Research Article 10.9734/jamps/2019/v21i430139