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All published articles 883

Simultaneous Quantification of Acetaminophen, Caffeine, and Ibuprofen in Fixed Dose Combination Drug Using HPLC with UV Detection

Emmanuel K. Darkwah, Christopher K. Acquah, Paul S. Lambon, David K. Ameko, Omotayo Akanji & John Sefah K. Ayim · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

Combination therapy of analgesics is well suited for pain management especially in elderly patients and, has been recommended by the World Health Organization (WHO). Drug analysis plays an important role in the development, manufacture and therapeutic use of drug. In this study,...

Open access Research Article 10.9734/jamps/2019/v20i230105

Comparative Antimicrobial Activity of Lemon Grass (Cymbopogon citratus) and Garlic (Allium sativum) Extracts on Salmonella typhi

O. F. Olukunle & O. J. Adenola · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

In the genesis of using plants for treatment of diseases, Garlic and lemon grass were some of the earliest plants that have proven effective. In this study the antimicrobial effect of Cymbopogon citratus (lemon grass) and Allium sativum (garlic) extracts on clinical isolate of Sa...

Open access Research Article 10.9734/jamps/2019/v20i230104

Evaluation of the Antimicrobial Potentials and Adverse Effect of Kolanut (Kola nitida Malvaceae) on the Oral Cavity and the Impact on Cariogenic Bacteria: A Socio-Demographic Study

Ashu Michael Agbor, Marie Ebob Agbor-Tabot Bissong, Estella Tembe-Fokunang, Clinton Eyong, Kaba KOUROUMA & Charles Ntungwen Fokunang · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

Kola nut (Kola nitida, Malvaceae) is one of the nuts consumed for socio-cultural reasons in West Africa sub-region and it has been used in Western African and Anglo-American herbal medicine as an antidepressant. The aim of this study was to evaluate the beneficial and adverse eff...

Open access Research Article 10.9734/jamps/2019/v20i130102

Centre-based Evaluation of Some Biochemical Effects of the Initial Phase of Anti-tuberculosis Therapy in Bayelsa State

Bonsome Bokolo, Ozakieoniso James Kemelayefa, Ray Ozolua & Fidelis Ching Poh · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

Aim of the Study: This study aimed at evaluating the adverse drug effects on some biochemical parameters of anti-tuberculosis drugs among patients with primary tuberculosis infection. Study Design: Non-probability (purposive) sampling technique was employed in this study.  Place...

Open access Research Article 10.9734/jamps/2019/v20i130099

Prevalence of Metabolic Disorder in Adolescent Residing in Al-dawadmi and Shaqra Regions of Saudi Arabia

Ghaith Saleh Suliman Alabdullatif, Hallal Badi Hallal Alotaibi, Sanjay Kumar Deshwali & Mohammad Arshad · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

The recent study was aimed to estimate the prevalence and develop the relationship of the clinical history like diabetes, cardiac disease and vitamin D deficiency and obesity and their impact on metabolic disorders for adolescent residing near Dawadmi and Shaqra region. Two hundr...

Open access Research Article 10.9734/jamps/2019/v20i130100

Relationship between Different Anthropometric Measurements and Interleukin-1β, Interleukin-17, Interleukin-27 and Interleukin-35 Levels for Iraqi Infertile Women with Polycystic Ovary Syndrome

Sundus Fadhil Hantoosh, Dheaa Shamikh Zageer & Farah T. O. Al-Jumaili · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

Aims: The study aimed to study impact of type and amount of body fat distribution on interleukin-1β, interleukin-17, interleukin-27, and interleukin-35 levels and on immunologic infertility. Study Design: The study was carried on infertile polycystic ovarian syndrome women. Place...

Open access Research Article 10.9734/jamps/2018/v19i430098

Analgesic and Anti-inflammatory Activities of Triterpenoid Molecules Isolated from the Leaves of Combretum glutinosum Perr. Ex DC (Combretaceae)

Madièye Sene, Daouda Ndiaye, Abdoulaye Gassama, Firmin Sylva Barboza, Mbaye Diagne Mbaye & S. Y. Guata Yoro · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

Combretum glutinosum Perr. Ex DC (COMBRETACEAE) is a traditional medicinal plant, widely distributed in Senegal and Africa. The aim of that study was to investigate the analgesic and anti-inflammatory activities of two triterpenes, betulonic acid (DN7) and cabraleone (DN12), isol...

Open access Research Article 10.9734/jamps/2018/v19i430096

Comparative Profiling of Solvent-mediated Phytochemical Expressions in Ocimum gratissimum and Vernonia amygdalina Leaf Tissues via FTIR Spectroscopy and Colorimetric Assays

Josephine Oluwagbemisola Tella & Saheed Oluwasina Oseni · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

Objective: The beneficial role of extraction solvents is often ignored, yet very important in enhancing the therapeutic potential of plant extracts. This study was carried out to comparatively characterize and profile the bioactive phytochemical compounds expressed in different s...

Open access Research Article 10.9734/jamps/2018/v19i430095

Chemical Characterization and In vitro Antimicrobial Activity of Caralluma europaea Essential Oil and Its Synergistic Potential with Conventional Antibiotics

Loubna Ait Dra, Abdellah Aghraz, Brahim Boualy, Saadia Oubaassine, Mustapha Barakate, Mohamed Markouk & Mustapha Larhsini · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

Aim: This study was carried out to investigate the antioxidant and antimicrobial activities of essential oil from the aerial part of Caralluma europaea and to evaluate the synergistic potential between essential oil and antibiotics. Methodology: The chemical composition, antioxid...

Open access Research Article 10.9734/jamps/2018/v19i430094

The Effect of Artemisinin-based Combination Therapy (ACT) Antimalaria Drugs on Liver Enzymes in Pregnancy

Ajibade Oluwagbenga Oyeyemi & Ayobola Abimbola Sonuga · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

Aims: Artemisinin-based Combination Therapies (ACTs) are employed as first-line agents in malaria chemotherapy. This study is aimed at assessing the effects of ACTs on renal function of pregnant women. Study Design: Comparative study. Place and Duration of Study: Pregnant women a...

Open access Research Article 10.9734/jamps/2018/v19i430093

Histological Effects and Prenatal Exposure to Crude Aqueous Extract of Morinda lucida Leaves on the Frontal Cortex of Growing Wistar Rats

O. O. Adeleye, A. A. Akande & A. A. Odetola · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

Background: The use of medicinal plants has always been part of human culture and is common in Africa. Amongst the medicinal plants commonly used in Nigeria for management/ treatment of various types of ailments is Morinda lucida Benth. Aims: This research work was designed to in...

Open access Research Article 10.9734/JAMPS/2018/46182

Basic Pharmacology of NG -Nitro – L – Arginine Methyl Ester

Muhanad S. Abdelwahab, Mukhallad A. M. Mohammed, H. M. Abdelwhab, Mazin S. Abdalla Mohamed & Mansour Abdelgader Bellal · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

NG – Nitro- L- arginine methyl ester (L-NAME) is a synthetic drug in which a quanidino is substituted for L-arginine analoques. It is a competitive enzyme inhibitor which inhibits nitric oxide synthase, hence, decreasing nitric oxide production [1].

Open access Research Article 10.9734/JAMPS/2018/46307

Haematologic and Gastric Histological Changes Associated with Administration of Ground Nutmeg (Myristica fragrans) Seed on Adult Male Albino Wistar Rats

Christopher Chiedozie Mbadugha, Gabriel Donatus Edem, Uka Emmanuel & Isaac Etim Udoudo · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

Introduction: Substantially unproven scientifically are numerous assumed health benefits of nutmeg, moreover, a few of the scientifically substantiated research done were on the nutmeg oil and the mace. There is paucity of data based on scientific protocol on research carried out...

Open access Research Article 10.9734/JAMPS/2018/46509