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All published articles 883

Dose-dependent Effect of Avocado Peel Hydroethanolic Extract on Antioxidant Status of Heart and Kidney Tissue Homogenates in Wistar Rats

Daniel Y. Onoja, Arthur N. Chuemere, Kolawole A. Tolunigba, Mobisson S. Kelechi & Ilochi N. Ogadinma · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

This study evaluated the dose-dependent effect of avocado (Persea americana) peel hydroethanolic extract on antioxidant status of heart and kidney tissue homogenates in wistar rats. A total of 60 wistar rats were used and the study period lasted for 42 days. The animals were rand...

Open access Research Article 10.9734/JAMPS/2018/46358

Potential Hazards of Ethanolic Extract of Garcinia kola on the Testes of Adult Male Wistar Rats

E. O. Nweke, J. K. Opara & I. J. Okafor · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

Background: Garcinia kola has been used in the treatment of a wide range of diseases and its importance in folkloric medicine is eminent. Aim: This study investigated the histological effect of ethanolic extract of G. kola on the testes of male Wistar rats. Materials and Methods:...

Open access Research Article 10.9734/JAMPS/2018/46524

Predictive Factors of Anaemia in Women in a Ghanaian Rural District

Dinah Asantewah Koranteng, Franklin Acheampong, Isaac Koranteng & Richard Adanu · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

Background: Anaemia is a condition of public health concern worldwide especially in developing countries. Anaemia falls in the top ten causes of morbidity in Ghana with a nationwide prevalence of about 45%. A rural district (Shai-Osudoku District), close to the capital city in Gh...

Open access Research Article 10.9734/JAMPS/2018/46017

Functional Compounds of Lobelia inflata Revealed Novel Potential Targets for Chronic Cough Therapy

Toluwase Hezekiah Fatoki, Olusola Olalekan Elekofehinti, Afolabi Clement Akinmoladun & David Morakinyo Sanni · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

Aim: To identify potential targets involved in chronic cough pathophysiology toward discovery and development of new therapeutants. Methodology: This work was carried out on bioactive compounds of selected medicinal plants with reference to known therapeutic agents using computat...

Open access Research Article 10.9734/JAMPS/2018/45276

Extracts of Ageratum Conyzoides L. Protects against Carbon Tetrachloride – Induced Toxicity in Rats through Inhibiting Oxidative Stress

Frederick Sarfo-Antwi, Christopher Larbie & Duduyemi Babatunde · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

Aims: The present study was aimed at investigating the hepatoprotective and nephroprotective activities of 50% hydroethanolic leave extracts of the Ageratum conyzoides and fractions on carbon tetrachloride - induced hepatotoxicity in rats. Study Design: A total of 30 Sprague Dawl...

Open access Research Article 10.9734/JAMPS/2018/45189

Determination of Haematocrit, Erythrocyte Sedimentation Rate (ESR) and Methaemoglobin Levels in Municipal Solid Waste Collectors (Sanitation Workers) in Port-Harcourt, Nigeria

Onengiyeofori Ibama & Felix Eedee Konne · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Aim: This study was carried out to ascertain whether or not occupational exposure affects the haematocrit, erythrocyte sedimentation rate, and methaemoglobin levels of municipal solid waste (MSW) collectors. Methodology: A total of 60 male subjects were recruited for this study,...

Open access Research Article 10.9734/JAMPS/2018/46187

Impacts of Analogy and Dimerization of Bioactive Compounds on Molecular Biological Functions

Toluwase H. Fatoki, Oladoja A. Awofisayo, Olusola A. Ogunyewo, Harriet U. Ugboko & David M. Sanni · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Aim: To determine the effect of analogy and dimerization of bioactive compounds at the molecular level on the biological functions. Methodology: This work was carried out on a model set of bioactive compounds which consisted of resveratrol, piceatannol, isorhapontigenin, scirpusi...

Open access Research Article 10.9734/JAMPS/2018/45211

Risky Sexual Behaviours among Youths in Selected Communities in Obio-Akpor and Ikwerre Local Government Areas of Rivers State, Nigeria

Nwondah, Chigozie & Alabere, Ibidabo · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Background: Youths are referred to as people of age group 15 to 24 years, and with significant physiological, psychological and social changes that place their lives at high risk. Risky sexual behaviour is the act of indulging in unprotected sexual intercourse through oral, anal...

Open access Research Article 10.9734/JAMPS/2018/45341

Phytochemical Screening and Antimicrobial Potential of Lepidium sativium and Rumex nervosus in Eritrea

Yohannes Solomon Ghebremariam, Mussie Sium Demoz & Natsnet Abraham Fissehaye · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Some of the widely used plants for the treatment of eye diseases, especially animals, include Lepidium sativium and Rumex nervosus. Therefore, the phytochemical screening and antimicrobial activities of the crude extracts of the seeds L. sativium and leaves of R. nervosus were in...

Open access Research Article 10.9734/JAMPS/2018/45664

Exploring the Knowledge, Attitude and Practices towards Use of Unprescribed Drugs among Adults of a Selected City of Somaliland

Salman Mohamed Farah, A. B. M. Alauddin Chowdhury, Kamrul Hossain, Masoud Mohammadnezhad & Russell Kabir · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Background: The emergence and spread of resistance related to the irrational use of antibiotics is a major global public health problem. The aim of this study was to assess Knowledge, Attitude and Practices towards use of unprescribed drugs among adults in a selected city of Soma...

Open access Research Article 10.9734/JAMPS/2018/45725

Antipsychotic Drugs Prescription Pattern among Patients with Schizophrenia in a Federal Neuropsychiatric Hospital Maiduguri, North East Nigeria

Paul Otor Onah, Ahmed Abdulmalik & Aliyu Ya’uba Kaigamma · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Introduction: Schizophrenia is a mental disorder characterised by delusions, disorganised thought and speech, hallucinations, blunted affect and reduced motivation among other clinical manifestations. Antipsychotic medications have demonstrated effectiveness in reducing symptoms...

Open access Research Article 10.9734/JAMPS/2018/40478

Investigation of Anti-diabetic Properties of Ethanol Leaf Extract of Bridelia stipularis L. on Alloxan Induced Type-2 Diabetic Rats

Abdus Sobahan Khan, Rajibul Islam, Md. Jahir Alam & Muhammed Mahfuzur Rahman · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Background: Type 2 diabetes mellitus (T2DM) is a chronic disease that is associated with insulin secretion, insulin action or both. Its development is directly connected with not only carbohydrate metabolism but also primarily on lipid metabolism. Oral hypoglycemic agents have be...

Open access Research Article 10.9734/JAMPS/2018/45396

Parenteral Antibiotic Use at a General Surgery Department of a Large Teaching Hospital in Ghana

Josephine Mensah, Mercy N. A. Opare–Addo, Franklin Acheampong & N. A. Adu Aryee · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Background: Inappropriate use of antimicrobial agents has been found to be common in developing countries where antibiotics are prescribed without indications and sometimes without bacteriological basis. This study evaluated the use of parenteral antibiotics at a general surgical...

Open access Research Article 10.9734/JAMPS/2018/45290

Antibacterial Activity and Fourier Transform Infrared Spectrometry of Study Moringa oleifera Leaf

F. O. Omoya, A. G. Ogunleye, K. J. Ayantola & O. A. Ajayi · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Introduction: In recent time, high incidence of resistance of microorganisms to antibiotics has increased the focus and demand for medicinal plants. Moringa oleifera is among such herbs with high demand that have served as sources of therapy to both man and animal. Aim: The aim o...

Open access Research Article 10.9734/JAMPS/2018/24700