Matrix metalloproteinases-2 belongs to gelatinase group of MMP family which are endopeptidases involved in the degradation of extracellular matrix proteins such as collagen, elastin, fibronectin or proteoglycans. MMPs play crucial functions in physiological processes such as embr...
Open access
Research Article10.9734/JAMPS/2018/42129
Ficus pumila Linn. has been reported to be rich in phenols, hepatoprotective and antiproliferative on leukemic cancer cells. The aim of this study was to evaluate the nephroprotective effect of hydroethanolic leaves extracts of F. pumila on gentamicin-induced kidney damage in rat...
Open access
Research Article10.9734/JAMPS/2018/41291
Diabetes mellitus is a global public health disorder that threatens the economies of all nations, particularly developing countries. In this study the comparative effects of the antidiabetic potentials of Glibenclamide and three well known plants used by our locals in the managem...
Open access
Research Article10.9734/JAMPS/2018/28981
A prospective observational study was carried out for the period of six months in inpatient department of General Medicine ward of a tertiary care teaching hospital at Vijayanagara Institute of Medical Sciences, Ballari, Karnataka. Objective: To assess and evaluate Prescribing Pa...
Open access
Research Article10.9734/JAMPS/2018/41622
Background: Oil exploration activities in the Niger Delta region may increase the risk of burns, and may occasionally require admission into the Intensive Unit. The pattern of admission of patients with Burns into the Intensive Care Unit in the hospital does not appear to follow...
Open access
Research Article10.9734/JAMPS/2018/41743
Toxicity investigation are employed in animal models to examine the dose level for the treatment of different disease for drug efficiency while phytochemicals are naturally occurring components found in medicinal plants containing varying colour, flavor and smell which serves for...
Open access
Research Article10.9734/JAMPS/2018/41425
Aims: To determine the influence of molecular properties upon the effectiveness of four peptide compounds to inhibit growth of Escherichia coli and show the potential of small molecule peptide drugs. Study Design: Examine molecular properties and extent of bacterial inhibition. U...
Open access
Research Article10.9734/JAMPS/2018/41548
The oxidative stress has been indicated to play an important role in the development and progression of diabetic complications such as decreased vascular reactivity, hypertension….etc. Previous studies show that Hibiscus sabdariffa possesses a hypoglycemic effect and useful in s...
Open access
Research Article10.9734/JAMPS/2018/37953
Introduction/ Background: Induced abortion is a major cause of maternal death and ill-health in developing countries, especially in those with restrictive abortion laws as in Nigeria. Antenatal subjects will form a window through which this aged-long procedure can be reappraised...
Open access
Research Article10.9734/JAMPS/2018/40680
Background: Patient-tested and -friendly information leaflets provide sufficient, accurate, and pertinent information about prescribed and over-the-counter medications to health consumers for their safety, enhanced satisfaction, improved outcomes and no medication errors across t...
Open access
Research Article10.9734/JAMPS/2018/41493
Typhoid fever is an essential communicable disease that is endemic in developing countries characterised by poor water supply, sanitary conditions and increasing population. Vaccination with the Salmonella typhi (ST) vaccine is an effective control measure. The two currently lice...
Open access
Research Article10.9734/JAMPS/2018/41329
Objective: To investigate the hypoglycemic activity of both ethanol extract Strophanthus hispidus root (EESHR) and chloroform extract Strophanthus hispidus root (CESHR) respectively. Methods: Both ethanol extract Strophanthus. hispidus root and chloroform extract Strophanthus. hi...
Open access
Research Article10.9734/JAMPS/2018/40393
Objectives: Studies have shown that both physical exercise and singing have beneficial medical effects on the cardiopulmonary functions of humans in health and disease conditions, but it is not yet known whether physical exercise or singing is more effective in producing these be...
Open access
Research Article10.9734/JAMPS/2018/40220
Aims: Currently there is enormous demand for skin-lightening agents, creating a quest for identification of new substances. Tyrosinase has become the main drug target for reducing skin pigmentation. The objective of this study was to detect tyrosinase inhibitory effects of eight...
Open access
Research Article10.9734/JAMPS/2018/40775
Quantitative structure-activity relationship (QSAR) models were combined with density functional computations and used to predict anti-fungi activities in a series of coumarin derivatives. Essential descriptors employed in this study were chosen based on the use of the Genetic Fu...
Open access
Research Article10.9734/JAMPS/2018/22801