Introduction: Hypospadia is one of the most common congenital abnormalities, yet the exact cause remains unknown. Androgen Receptor (AR) is suspected to cause hypospadias. Methods: As many as 49 post-operative prepuces of hypospadia patients and 49 normal prepuces from elective c...
Open access
Research Article10.9734/JAMPS/2017/34294
Aims: A new hydrophilic cellulose polymer (I-hydrocel) derived from the tubers of Ipomoea batatas was assessed as a tablet disintegrant in paracetamol tablet formulation in comparison with maize starch. Methods: I-hydrocel was incorporated intragranularly at 5, 10 and 15% w/w to...
Open access
Research Article10.9734/JAMPS/2017/37119
Background: Flour dust is a respiratory sensitizer and chronic exposure to it and to Carbon Monoxide as a result of burning fossil fuel could affect the pulmonary functions and stimulate allergic responses. This study is designed to determine occupational related respiratory symp...
Open access
Research Article10.9734/JAMPS/2017/37903
Objective: To evaluate the routine histopathological analysis of foreskin in adult patients and determine whether histological processing is necessary in patients with non-suspicious foreskin. Materials and Methods: All adult foreskin sent for histopathological analysis between...
Open access
Research Article10.9734/JAMPS/2017/38117
Background: Berberine (BB) is a protoberberine alkaloid with a wide spectrum of pharmacological activities considered to be a selective Janus kinase (Jak)3 inhibitor. Nevertheless, the mechanisms of berberine’s actions on joint inflammation have not been well clarified. Aim: This...
Open access
Research Article10.9734/JAMPS/2017/37839
This study investigated the in vitro comparison of metronidazole and tinidazole activity against Trichomonas vaginalis strains from internally displaced women in Maiduguri, Nigeria. Materials and Methodology: high vaginal swab samples were collected from (41) T. vaginalis positiv...
Open access
Research Article10.9734/JAMPS/2017/36205
Introduction: There has been sufficient awareness on atherosclerosis but this has not reduced the number of people with it. Atherosclerosis is promoted by low density lipoprotein (LDL) without sufficient removal of fats and cholesterol by high density lipoprotein (HDL). Stress is...
Open access
Research Article10.9734/JAMPS/2017/37768
Introduction: The available evidences indicate that nocturnal enuresis has multi-factorial etiology and this may underlie the wide range of outcomes. Various pathophysiological mechanisms have been discussed and succeeded in defining many causes of enuresis such as disturbed func...
Open access
Research Article10.9734/JAMPS/2017/37732
Aims: This work examines a novel hydrophilic biopolymer, I-polygel derived from Ipomoea batatas tubers (Convolvulaceae) as a suspending agent in sulphamethoxazole suspension using acacia and tragacanth respectively as comparing standards. Methods: Aqueous suspensions of sulphamet...
Open access
Research Article10.9734/JAMPS/2017/37028
Background: Urinary tract infections (UTIs) are the second most common form of infectious diseases that affect humans after respiratory diseases. It is predicted that 20% of the adult female population is exposed to development of an UTI. The emergence of UTIs is promoted by the...
Open access
Research Article10.9734/JAMPS/2017/37419
Background: The resistance of Plasmodium species to drugs has necessitated the search for more potent drugs. Anogeissus leiocarpus and Terminalia avicennioides have been considered traditionally for the treatment of malaria. Aim: This study assessed the efficacy of combination th...
Open access
Research Article10.9734/JAMPS/2017/35105
H. C. C. Maduka, A. A. Maduka, C. U. Aguoru, B. K. Myke-Mbata, J. O. Ikwue, A. N. Okpogba, C. E. Ugwu, C. C. Dike, P. N. Ogueche, D. O. Ochalefu, Nath Ufaryna, J. Yakubu & E. Shatar·Journal of Advances in Medical and Pharmaceutical Sciences·2017
Aims: To screen Crateva adansonii phytochemically for phytosterol, phenol, proteins, amino acids, and to determine the pigment levels in Crateva adansonii using various types of solvents. Study Design: This study was designed to determne the pigment levels in the extracts of diff...
Open access
Research Article10.9734/JAMPS/2017/30052
Background: Children with thalassemia major need regular blood transfusions to survive. These multiple transfusions put them at risk for iron overload, which result in organ damage such as parathyroid gland. The aim of this study is to determine levels of calcium, phosphorus, vit...
Open access
Research Article10.9734/JAMPS/2017/35473
Fresh samples of leaves and roots of Thunbergia grandiflora were collected from forest- reserved area, Ibadan, Nigeria for extraction of their volatile oils. Hydro-distillation method was used in an all-glass Clevenger apparatus designed to British pharmacopeia specifications. It...
Open access
Research Article10.9734/JAMPS/2017/35836
Background: Black box warnings indicating harmful or potentially fatal adverse events are required by the Food and Drug Administration on certain drugs and chemical entities; however it is unclear if prescribing and dispensing habits are impacted by these warnings. This study inv...
Open access
Research Article10.9734/JAMPS/2017/36666