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All published articles 883

Evaluation of the Activity of Lippia alba Leave Extract in Reducing Ochratoxin A in Albino Rats

Olukayode Olugbenga Orole, Timothy Olubisi Adejumo & Japhet Erasmus Aisoni · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Ochratoxin A is a metabolite of fungal origin with the potential of inciting oxidative stress which results in disease conditions in man and animals. Plant parts from time immemorial have been used to treat disease conditions with considerable success, hence the study is aimed at...

Open access Research Article 10.9734/JAMPS/2017/35875

Knowledge, Attitude and Practice towards Antibiotics Use among Non-medical University Students in Uyo, Nigeria

Ifunanya Evangeline Asogwa, Samuel James Offor & Herbert Orji Chidi Mbagwu · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Background: The widespread use, misuse and overuse of antibiotics in human and veterinary medicine have resulted in emergence and spread of antibiotics resistance consequently decreasing their effectiveness and efficacy. Recent studies consistently reveal that university students...

Open access Research Article 10.9734/JAMPS/2017/35671

Effect of Ethanolic Leaf Extract of Sarcocephalus latifolius on Some Biochemical Parameters in Alloxan Induced Diabetic Rats

M. N. Ndukwe, G. I. Adoga & C. D. Luka · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

This research project was carried out to investigate the biochemical effect of Sarcocephalus latifolius leaf extract in alloxan induced diabetic rats. The study was carried out for about 12 months in the department of Biochemistry University of Jos, Jos, Nigeria and Prestige medi...

Open access Research Article 10.9734/JAMPS/2017/34311

Intramedullary Interlocking Nailing for Long Bone Fractures of the Lower Limbs: Our Experience with Free-hand Locking

Shamsuddeen Muhammad & Abdurrahman Alhaji Mamuda · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Aims: To see the pattern of interlocking nailing used for fractures of lower limb’s long bones in terms of the bone affected, laterality, age distribution, sex distribution, pattern of locking and early outcome. Study Design: The study is a retrospective cross sectional study con...

Open access Research Article 10.9734/JAMPS/2017/35079

Rat Serum Electrolytes and Lipid Profiles Following Administration of Aqueous Extract of Sphenostylis stenocarpa

Okoye Ngozi Franca & Dimkpa Precious Isioma · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Aim: Aqueous extract of the seed of African yam bean (Sphenostylis stenocarpa) is used in Nigerian alternative medicine for the treatment of high blood pressure. Therefore the aim of this study is to investigate the effect of Sphenostylis stenocarpa seed extract on some electroly...

Open access Research Article 10.9734/JAMPS/2017/34369

The Frequency of CYP3A5 Expression in a Mexican Population Compared to a Caucasian Population

Jason W. Guy, Arthur F. Harralson, Kylie Pooler & Robert S. Kidd · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Aims: To determine the frequencies of the six most common CYP3A5 alleles and genotypes in a Mexican-American population compared to a non-Hispanic Caucasian population.  Study Design: This cross-sectional study compared the frequency of CYP3A5 genetic variations in a Mexican-Amer...

Open access Research Article 10.9734/JAMPS/2017/35168

The Phytochemical and Antimicrobial Potentials of the Crude Extracts of Bridelia ferruginea and the Extracellular Biosynthesized Silver Nanoparticles

Temitayo Omotola Akinsete, Bukola Christianah Adebayo-Tayo & Abimbola Olumide Adekanmbi · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Bridelia ferruginea has been used in African folk medicine for the treatment of several ailments especially throat infections. In this study, the phytochemical analysis, fractioning using different solvents, antimicrobials and silver nanoparticles (SNPs) produced by the ethanolic...

Open access Research Article 10.9734/JAMPS/2017/34172

The Use of Modular Distal Aiming Device (MODAD) System for Locked Intra-medullary Nailing for Fixation of Fractures in Nigeria: A Prospective Observational Study

S. E. B. Ibeanusi · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Locked intra medullary nailing has been accepted globally as the gold standard for treating fractures of the shaft of long bones. The method provides acceptable stabilisation of the fracture, controls alignment, axial translation and rotational deformity at the fracture. The chal...

Open access Research Article 10.9734/JAMPS/2017/34680

Pattern of Adverse Drug Reaction to Antiepileptic Drugs at a Tertiary Hospital in North-Central Nigeria: A Prospective Observational Study

Emeka U. Ejeliogu & Aderonke Uhunmwangho-Courage · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Background: Epilepsy is a common neurologic condition affecting 0.5-1% of the popula­tion. Adverse drug reactions (ADRs) are a major health problem to the individual as well as for the society. There is insufficient awareness and inadequate training on drug safety monitoring amon...

Open access Research Article 10.9734/JAMPS/2017/35337

End-of-life Care in Nigeria: Preparing Nursing Students and Workforce to Take the Lead

Peretomode Evans & Udo Eunice · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

In this 21st century, several factors have informed the increasing need of end-of-life care globally. Notable amongst them are the global changes in both demographic and disease pattern; factors that have led to increasing number of chronic illnesses. Individuals suffering from c...

Open access Research Article 10.9734/JAMPS/2017/34876

Do Iron Chelators Affect Fertility in Thalassemic Men?

Shahla Ansari, Azadeh Kiumarsi, Azita Azarkeivan, Mohammad Mahdi Allameh, Maryam Razzaghy-Azar & Davoud Amirkashani · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Background: Iron overload is a major complication in patients with thalassemia, however, development of iron-chelating therapy has partly overcome this problem. Objectives: The aim of this study was to evaluate the effect of iron chelator drugs on testicular volume, semen paramet...

Open access Research Article 10.9734/JAMPS/2017/33728

Saponin Fraction of Gongronema latifolium Reverses Dyslipidemia and Catalyzes Glucokinase in Lowering Blood Glucose Sugar in Streptozocin-Induced Diabetic Rats

G. O. Igile, I. A. Iwara, O. O. Ekpe, B. I. A. Mgbeje & M. U. Eteng · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Objective: Gongronema latifolium (GL) is a bitter tasting leaf used in Nigeria as spice in food, and as herb for the treatment of diabetes, malaria and cardiovascular disease. Research work on the anti-diabetic activities of the whole leaf extract has been carried out, but none o...

Open access Research Article 10.9734/JAMPS/2017/34310

Quality Control Tests for Ophthalmic Pharmaceuticals: Pharmacopoeial Standards and Specifications

Md. Sahab Uddin, Abdullah Al Mamun, Md. Tanvir Kabir, Jinnat Ruksana Setu, Sonia Zaman, Yesmin Begum & Md. Shah Amran · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

The therapeutically performance of the pharmaceuticals must be constant and expectable.  In order to claim a pharmaceutical to be a quality drug, it must fulfill certain standards and specifications. The quality of pharmaceuticals is strongly related to the patient’s well-being....

Open access Research Article 10.9734/JAMPS/2017/33924

In vivo-Study of Antiviral Effect of Gossypium hirsutum Extract on Newcastle Disease Virus

G. Ezeifeka, P. Nwiyi, U. Effiong, I. Ukwueni, I. Erumaka, A. Onyeabor, I. O. Oguoma & N. Amaechi · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Gossypium hirsutum belongs to the family Malvaceae and genus Gossypium, the name of the genus is derived from the Arabic word goz, which refers to a soft substance. This plant occupies a very important position in traditional medicine because of its ethnomedicinal value. The aim...

Open access Research Article 10.9734/JAMPS/2017/34530