Skip to content

All published articles 883

Assessment of Pyrazinamide-Associated Hyperuricemia Among Multidrug-Resistant Tuberculosis Patients Receiving Pyrazinamide-Containing Regimens: A Retrospective Cross-Sectional Study from Sudan

Mayada E. Abdelrahman, Fatima S. Naim, Mawahib A. Mustafa, Elkhanssa Abdelhameed Ahmed Elhag, Mohammed H. Alnazeer, Kannan O. Ahmed, Orwa Siddig & Bashir A. Yousef · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Background: Tuberculosis (TB) is still one of the most important causes of morbidity and mortality worldwide. The problem multiplies whenever there is multidrug-resistant TB (MDR-TB), due to Mycobacterium tuberculosis susceptibility to both Rifampicin and Isoniazid. Pyrazinamide...

Open access Research Article 10.9734/jamps/2025/v27i12834

Education, Advocacy and Action for Prevention of Sudden Cardiac Death in Student Athletes in American Samoa

Zain Jandial, Greg Whyte & Raynald Samoa · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Background: Sudden Cardiac Death (SCD) is one of the common causes of death in young athletes, especially during exercise, and it continues to be a challenge. Although the incidence of SCD among the aged is low, this problem has strong emotional and societal implications. Hypertr...

Open access Research Article 10.9734/jamps/2025/v27i12833

Assessment of Prescribers’ Knowledge, Diagnostic Decision-Making, and Rational Antimalarial Drug Use in the Management of Uncomplicated Malaria in the Buea Health District, Cameroon

NNOKO SONA AKWO, David OBEN BATE, ABUUCHICHE Faith BENYWEI, ENOW NKAH Bruno ENOW, NTUNGWE EKWELLE Smith & EBOUMBOU MOUKOKO Carole · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Malaria remains a leading cause of morbidity and mortality in Cameroon. The national policy, aligned with WHO guidelines, mandates parasitological confirmation via microscopy or Rapid Diagnostic Tests (RDTs) before treatment with Artemisinin-based Combination Therapy (ACT) for un...

Open access Research Article 10.9734/jamps/2025/v27i11832

Effect of Holding Time on Residual Leucocyte Counts and Protein Concentration in Unfiltered Fresh Frozen Plasma

Yousif, D., Sammut, M. & Zammit, V · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Ensuring the safety and quality of transfusion products is critical in transfusion medicine. Leucocytes in blood products can cause adverse reactions and increase the risk of transfusion-related complications, making it essential to minimize their presence before transfusion. Ele...

Open access Research Article 10.9734/jamps/2025/v27i11831

Factors Affecting Treatment Outcomes among Tuberculosis Patients during 2019- 2024: A Study from a University Teaching Hospital in South Eastern Nigeria

Chioma V. Francis, Nzube F. Ekpunobi, Nwasoluchukwu Obidi, Chidozie N. Ibezim & Malachy C. Ugwu · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Background: Tuberculosis (TB) remains a major public health problem in Nigeria, where treatment success is impacted by various factors including poor adherence, adverse drug effects, and systemic barriers. Understanding local treatment outcomes and associated factors are essentia...

Open access Research Article 10.9734/jamps/2025/v27i11830

A Comprehensive Review on the Health & Ecological Impacts of Chromium, Cadmium and Lead Contamination

Farjana Akter, Sourav Das, Tasnuva Sharmin, Md. Rafat Tahsin, Md. Shah Amran & Fahima Aktar · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Environmental systems are increasingly being polluted by heavy metals especially chromium(Cr), cadmium(Cd), and lead(Pb) which are highly dangerous to both the ecosystems and human health. A thorough literature search was carried out utilizing databases like PubMed, Scopus, Googl...

Open access Research Article 10.9734/jamps/2025/v27i11829

Development and Validation of New Analytical Method for the Determination of Particle Size Distribution in Empagliflozin Using Laser-Based Particle Size Analyzer

Jitendra Dubey, Bakul Rajyaguru, Kushal Vankawala, Frenil Vaidya, Jeelkumari Mistri & Kishan Surati · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

This paper describes a rugged and precise analytical method developed and validated for determining the particle size distribution of Empagliflozin drug substance using a wet dispersion technique on the Malvern Mastersizer 3000. The method was optimized to achieve uniform dispers...

Open access Research Article 10.9734/jamps/2025/v27i11828

Therapeutic Potential of Agaricus bisporus Extract against Oxidative Stress in Isoproterenol-Induced Myocardial Infarction: An Experience with Wistar Rats

Onwubuya, E. I., Kalu, O. A., Oladejo, A. A., Okeke, C. B., Okeke, C. M., Adeyemi, M. A., Anyanwu, R. O. & Ndumka, C.L. · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Background: Agaricus bisporus (A. bisporus) is an edible mushroom native to grasslands in Europe and North America. A. bisporus, commonly known as white button mushroom (WBM), is widely grown in most countries, especially in United States, Australia and Nigeria. Traditionally, th...

Open access Research Article 10.9734/jamps/2025/v27i11827

Governance and Accountability of AI Agents in U.S. Healthcare Systems: Ethical and Regulatory Perspectives

Emmanuel Ahaiwe, Godwin Okwara, Onyinye Faith Mbanefo, Kelvin Ebo Rabbles & Philip Williams Appiah-Agyei · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

AI agents are moving from pilot to routine use in U.S. healthcare, yet evidence, transparency, and governance remain uneven. This systematic review examined how lifecycle safeguards spanning design, validation, deployment, and post-market monitoring affect patient outcomes and in...

Open access Research Article 10.9734/jamps/2025/v27i11826

Trimethylamine N-Oxide: A Dual-function Compound at the Intersection of Gut Microbiota Metabolism and Systemic Disease

Ali Danish Alvi, Ye Zhao, Zaid Iqbal, Muhammad Abubakar, Mirza Zeeshan Afzal & Arslan Habib · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Trimethylamine N-oxide (TMAO) is a dietary metabolite at the intersection of microbiota metabolism and host response. Chronically elevated TMAO has been associated with negative outcomes in cardiovascular, renal, and neurological disease and, at physiological levels, appears to s...

Open access Research Article 10.9734/jamps/2025/v27i11825

Ameliorative Effects of Ethanolic Extract of Vernonia amygdalina Leaves on Testicular Damage in Alloxan-Induced Diabetic Male Wistar Rats

Ezenwatu E. N. & Nweke O. E. · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Aim: To evaluate the ameliorative effects of ethanolic extract of Vernonia amygdalina leaves on testicular damage in alloxan-induced diabetic male wistar rats. Methodology: Thirty adult male Wistar rats were randomly divided into six groups (A–F, n = 5). Group A served as control...

Open access Research Article 10.9734/jamps/2025/v27i11824

Balancing the Therapeutic and Adverse Effects of Oral Prednisone/Prednisolone: A Systematic Review

Samuel James Offor, Victory Edet Iyanam, Ekpeno Mbet Akpanowo & Uduak Ugonma Ndubuisi-Nnaji · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Prednisone and prednisolone are synthetic analogues of the natural steroid hormones produced by the adrenal cortex. They have anti-inflammatory, and immunosuppressant effects. Prednisone is biologically inert and in order to become active, it is converted to prednisolone in the l...

Open access Research Article 10.9734/jamps/2025/v27i10822

Computational Evaluation of Indole Alkaloids from Rauwolfia vomitoria as Potential Anticancer Agents: Molecular Docking and ADME Profiling

Nzube F. Ekpunobi, Sandra C. Okoye, Eddison I. Oghonyon, Chidimma R. Chukwunwejim, Merylann A. Ochieng, Oluwatosin T. Idowu, Sabbath Usen-Obong, Matthew O. Olushola & Agu, K.C · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Background: Cancer continues to pose a major global health challenge, particularly in low- and middle-income countries, where treatment costs and accessibility remain limiting. Natural products such as Rauwolfia vomitoria have shown significant promise as alternative sources of b...

Open access Research Article 10.9734/jamps/2025/v27i10823

The Concept of Cell Generation to Patient-Specific Therapy: A Review of Induced Pluripotent Stem Cell Applications

Darren Toritseju Amiwero & Christian Esidogho Amiwero · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Induced pluripotent stem cells (iPSCs), are derived from the reprogramming of adult somatic cells and have become essential in biomedical research. Their pluripotency nature allows these cells to be converted into specific cell types for therapeutic applications. This article rev...

Open access Research Article 10.9734/jamps/2025/v27i10821

Comprehensive Physicochemical Characterization and GC-MS Profiling of Neelibhringadi Kera Tailam: A Traditional Ayurvedic Oil Formulation for Hair Growth

Maneesha KS, Reeshma CR, Anagha Mariya & Sibi Narayanan · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Introduction: Neelibhringadi Kera Tailam is a traditional Ayurvedic herbal oil formulated for promoting hair health, addressing issues such as hair loss, premature greying, scalp irritation, and infections. This study evaluates its composition, preparation, organoleptic, physicoc...

Open access Research Article 10.9734/jamps/2025/v27i10820