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All published articles 883

Cardiotoxic Assessment of Radiographic Developer Effluent in Wistar Rats

A. C. Ugwu, U. Dimkpa, D. Fotso, A. N. Eteudo, S. O. Maduka, N. N. Njoku-Oji, L. C. Anikeh & R. C. Uchefuna · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Aims: To demonstrate the histopathological changes in cardiac tissues of Wistar rats following exposure to developer effluent. Study Design: A case control study. Place and Duration of Study: Department of Radiography, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Niger...

Open access Research Article 10.9734/JAMPS/2016/23330

Four Compounds Suppressing Growth of Mycobacterium tuberculosis

Ronald Bartzatt, Preeti Sule, Woojung Kim & Jeffrey D. Cirillo · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Aims: To demonstrate the efficacy of several small molecular weight compounds having hydrazide groups, for inhibiting the growth of Mycobacterium tuberculosis. To show these same compounds have favorable drug-likeness properties.  Study Design: To synthesize tuberculostats and te...

Open access Research Article 10.9734/JAMPS/2016/24351

Cysteine Protease Inhibitors from Calotropis procera with Antiplasmodial Potential in Mice

Abdullahi Abdulkadir, Ismail Alhaji Umar, Sani Ibrahim, Elewechi Onyike & Adamu Yusuf Kabiru · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Inhibitory activity of crude extract of cysteine protease inhibitors from Calotropis procera against Plasmodium berghei infected mice was investigated. Various extracts obtained from the leaves, roots, flowers, latex and stem bark of Calotropis procera using different extraction...

Open access Research Article 10.9734/JAMPS/2016/22866

Prevalence and Clinicoradiological Profiles of Respiratory Dysfunction in Patients with Medullary Infarction: Retrospective Case Study and Review of Literature

Masahiro Sawada, Takanori Takazawa, Ken Miura, Tetsuhito Kiyozuka & Ken Ikeda · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Background: Respiratory dysfunction occurs in stroke patients. Little is known about the prevalence, clinical features and lesion topography in patients with dyspnea due to medullary infarction (MI). We aimed to evaluate the frequency and the clinicoradiological profile in dyspni...

Open access Research Article 10.9734/JAMPS/2016/24206

Acute Toxicity and Hypoglycemic Activity of Aqueous Fruit Pulp Extract of Adansonia digitata L. (Afpead) on Alloxan Induced Diabetic Rats

I. U. Muhammad, I. K. Jarumi, A. J. Alhassan, A. M. Wudil & M. A. Dangambo · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Oral LD50 and hypoglycemic activity of aqueous fruit pulp extract of Adansonia digitata L. (AFPEAD) were investigated in this research. A total of fourty eight (48) rats were used, twelve (12) of the rats were used for oral LD50 determination, and were grouped into four (4) group...

Open access Research Article 10.9734/JAMPS/2016/23862

Influence of Active and Passive Smoking on the Urinary Concentration of 1 Hydroxyl Pyrene, Oxidative Stress and Renal Activity in Male Subjects

H. K. Okafor, S. E. Omogo & Y. A. Omoniyi · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Objective: The purpose of the study was to investigate the influence of active and passive smoking on the urinary concentration of 1 hydroxyl pyrene, oxidative stress and renal activity in male subjects. Methods: Urine samples each of forty active and passive smokers including fo...

Open access Research Article 10.9734/JAMPS/2016/23966

A Straightforward and Receptive UV Spectrophotometric Method for the Determination of Ibandronate Sodium in Pharmaceutical Formulations and Bulk Drugs

Lubna Azmi, Ila Shukla, Shyam Sundar Gupta, Paramdeep Bagga & Ch. V. Rao · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Aims: A uncomplicated and outlay efficient spectrophotometric method is developed for the determination of Ibandronate sodium in unadulterated form and in pharmaceutical formulations. Place and Duration of Study: Department of Pharmacognosy and Ethnopharmacology Division (Pilot p...

Open access Research Article 10.9734/JAMPS/2016/20079

Knowledge, Attitude and Practice about Household Poisoning in Saudi Arabia

Samia S. Barghash, Azza El. Tlt & Huda A. Al-Jemily · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Background: Food poisoning, household poisoning, and cosmetic poisoning are becoming a very important health problem both worldwide and locally at the level of the Kingdom of Saudi Arabia (KSA). The aims of this study was to assess knowledge, attitude and practice about the stora...

Open access Research Article 10.9734/JAMPS/2016/23115

Antibacterial Efficacy of Ageratum conyzoides on Salmonella Species Isolated from Suspected Typhoid Fever Patients in Akure Metropolis, Nigeria

O. E. Ajayi, S. I. Awala, F. N. Okogbue, A. G. Ogunleye & B. F. Olaleye · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Aim: The study aimed at assessing the antibacterial efficacy of Ageratum conyzoides on Salmonella species isolated from suspected typhoid fever patients in Akure metropolis, Nigeria. Study Design: The study evaluated the prospective use of Ageratum conyzoides as an alternative to...

Open access Research Article 10.9734/JAMPS/2016/23307

Association of Butterfly Rash and Antinuclear Antibody Positivity with Inflammatory Bowel Disease

Akkamahadevi V. Nipanal, M. Parvathi, R. Madhumathi, K. V. Sanathkumar & Chandramohan . · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

A 30 year old female presented with diarrhoea and gastrointestinal bleeding, along with photosensitive rash over malar region of face. Clinically she had features of essential nutrients deficiency, extra intestinal manifestations of inflammatory bowel disease and malar rash typic...

Open access Research Article 10.9734/JAMPS/2016/22595

Ulcerated Giant Lipoma over Nape of Neck – A Rare Case

Dinesh Kumar Barolia & Devendra Atal · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Lipoma is a benign tumor composed of fat cells of adult type. It is a universal tumor as it can occur anywhere in body. Lipoma with size of more than 10 cm in one dimension or weighing a minimum of 1000 gm. called as giant lipoma [1]. Surgical excision is the treatment of choice...

Open access Research Article 10.9734/JAMPS/2016/23250

Comparative Studies on the Phytochemical Properties of Five Nigerian Medicinal Plants

C. Egbuna & J. C. Ifemeje · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Aims: This work investigated the phytochemical composition of five Nigerian medicinal plants and the significance of the phytochemicals with respect to the treatment of diseases were discussed. Study Design: Fifteen phytochemicals were qualitatively analysed from the plants ethan...

Open access Research Article 10.9734/JAMPS/2016/21816

A ‘Single Point’ Experimental Approach of Assessing the Inactivation Kinetics of β-glucuronidase by Aqueous-based Leaf Extractives Notably Used as Enemas

Kwabena J. Sarfo & Caleb M. Abgale · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Excess beta-glucuronidase in the caecum and colon is responsible for enterohepatic circulation of toxic aglycones, which have been implicated in development of cancer, diarrhea, jaundice and other disease conditions of the gut. Botanicals are potential sources of molecules, which...

Open access Research Article 10.9734/JAMPS/2016/22249

Antibacterial Activity of Essential Oil of Corymbia citriodora Leaves against Escherichia coli and Staphylococcus aureus

Edward Missanjo & Idah Mkwezalamba · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Aim: To examine the antibacterial activity of essential oil of Corymbia citriodora leaves on two clinically significant microorganisms, Escherichia coli and Staphylococcus aureus. Place and Duration of the Study: The experiment was conducted in Science Laboratory at Malawi Colleg...

Open access Research Article 10.9734/JAMPS/2016/23172