Objective: To investigate the anti-inflammatory activity of the chloroform extract of the fruit of Tetracarpidium conophorum (CEFTC). Methods: CEFTC was evaluated for anti-inflammatory activity using standard formalin-induced rat paw edema. The activities of the extract at diffe...
Open access
Research Article10.9734/JAMPS/2016/22898
The potential renal toxicity of monosodium glutamate (MSG) following dietary administration for four weeks in Albino rats was preliminary investigated by the measurement of serum electrolytes, urea and creatinine levels. The rats were randomly divided into four (4) groups based o...
Open access
Research Article10.9734/JAMPS/2016/19825
Aim: To determine the differences in H2O2-clearance of two prostate cancer cell lines PC-3 and LNCaP treated with peroxisome proliferator-activated receptor gamma (PPAR-γ) ligands 15-deoxy-Δ 12, 14 – prostaglandin J2 (PGJ2) and nafenopin (Naf) Study Design: Catalase activity in c...
Open access
Research Article10.9734/JAMPS/2016/20795
Aims: To investigate the in-vitro and in-vivo activities of the crude ethanolic extract of unripe Anonna muricata fruits in albino rats infected with Salmonella typhi. Methodology: Matured unripe fruits of A. muricata were collected, dried, powdered and extracted using 70% ethano...
Open access
Research Article10.9734/JAMPS/2016/22457
Background: The objective of this study is to investigate the anticancer activity of ethanolic extract of Alpinia galanga Willd (galangal) on breast adenocarcinoma cells transplanted in C3H mice. In some previous studies ethanolic extract of galangal containing active substance i...
Open access
Research Article10.9734/JAMPS/2016/22301
Introduction: Hypospadias is the result of an abnormal growth of penis in which the failure of the growth of urethral fold that resulted in the urethral meatus at ventral penis is located proximal from its normal position in glanular with or without chorde. The incidence of hypos...
Open access
Research Article10.9734/JAMPS/2016/22574
Aim: To investigate quantum characters of the microRNA (miRNA) gene as the disease memory device, at the beginning, a novel quantum scoring method was developed and its usability was confirmed by valuating miRNA–miRNA interaction. Background: In general, activated miRNAs particip...
Open access
Research Article10.9734/JAMPS/2016/22134
Moringa oleifera is a plant that has huge nutritional and phytomedicinal values particularly due to its rich nutrients, antioxidants and medicinal phytochemicals. This investigation examined the effect of Moringa oleifera leaf extract on the histology of the prefrontal cortex of...
Open access
Research Article10.9734/JAMPS/2016/15989
This study evaluated the effects of different concentrations of quail egg solution on glycemia and some antioxidant markers in alloxan-induced diabetic rats. Thirty adult male albino rats were assigned to 5 groups of 6 rats per group. Groups 2, 3, 4 and 5 were made diabetic by si...
Open access
Research Article10.9734/JAMPS/2016/22723
Paracetamol (acetaminophen) with caffeine is a combination medicine indicated for the temporary relief of pain and discomfort associated with a number of conditions such as headache or muscle pain. There is a controversy going on this combination concerning their safety in patien...
Open access
Research Article10.9734/JAMPS/2016/22198
Resveratrol is a potent antioxidant, demonstrated to ameliorate adverse effects of heat stress-induced toxicity. Information on the ameliorative effect of resveratrol on heavy metals induced organ toxicity is scanty. The aim of this experiment was to investigate the effect of res...
Open access
Research Article10.9734/JAMPS/2016/21835
Aims: To further investigate quantum characters of the microRNA (miRNA) gene as the disease memory device, we calculated neo-score tool for miRNA/miRNA multi-interaction. Since the potential miRNA/target interaction is not one-to-one correspondence; therefore, the network of miRN...
Open access
Research Article10.9734/JAMPS/2016/22095
The plant Morinda lucida falls under the family Rubiaceae known to have wide usage in traditional medicine. Morinda lucida is a tropical West African tree of medium-size about 18–25 m tall, the bark is grey to brown in colour, flowers are white in colour, the fruit is a drupe, se...
Open access
Research Article10.9734/JAMPS/2016/20705
Academic institutions have plentiful of unexploited compounds. A cost-effective repositioning strategy from abandoned molecules coming from different research projects was applied. This strategy was based on the creation of a 2D-database then the biological assaying following adh...
Open access
Research Article10.9734/JAMPS/2016/22023
Aim: Integrase inhibitors are an essential enzyme required for replication of the acquired immunodeficiency syndrome virus. It is a potent target for anti- HIV therapy. A QSAR study is performed on the series indole -diketo, diketo acid and carboxamide derivatives in order to ana...
Open access
Research Article10.9734/JAMPS/2016/22227