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All published articles 892

Safety Evaluation of Giant African Land Snails (Archachatina maginata) Haemolymph on Hematological and Biochemical Parameters of Albino Rats

L. Bashir, O. K. Shittu, M. B. Busari, S. Sani & M. I. Aisha · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

The safety of Archachatina maginata haemolymph on biochemical and hematological indices of albino rats was investigated. Twelve white albino rats were grouped into 3 (A-C) of 4 animals each. Group A rats serve as control groups and received no treatment, while groups B and C rece...

Open access Research Article 10.9734/JAMPS/2015/16393

Experimental Evaluation of Analgesic and Antioxidant Effects of Hydromethanolic Extract of Dioscorea dumetorum Tuber

Celestine O. Ukwueze, Samuel O. Onoja & Maxwell I. Ezeja · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Aims: The hydromethanolic extract of D. dumetorum was evaluated for antinociceptive and antioxidant activities to validate its uses in traditional medicine for these purposes. Methods: The antioxidant activity of D. dumetorum was done in vitro using 2, 2-diphenyl-1-picrylhydrazyl...

Open access Research Article 10.9734/JAMPS/2015/18117

Comparative Assessment of the Gastrointestinal Tolerability, Anti-inflammatory and Antipyretic Effects of Diclofenac, Ibuprofen and Nimesulide in White Albino Rats

C. O. Ukwueze, C. S. Ukwueze & E. C. Nweze · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Aim: NSAIDs is among the commonly used drug in the management of disease conditions. The study carried out comparative assessment of gastric tolerability, antipyrectic and anti inflammatory effect of diclofenac, ibuprofen and nimesulide in rats. Methods: The rats were randomly di...

Open access Research Article 10.9734/JAMPS/2015/17037

Drug Release Modification by Using Citric Acid and Glycerol Cross-linked Derivatives of Cashew (Anacardium occidentale L.) Gum

A. Abdulsamad, A. R. Oyi, A. B. Isah & I. Odidi · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

A derivative of cashew gum (CrosCCG) developed by cross-linking the gum with two cross-linking agents, citric acid and glycerol, has been used to modify drug release in Venlafaxine Hydrochloride tablets. Wet granulation method was used to formulate the tablets using hydroxypropyl...

Open access Research Article 10.9734/JAMPS/2015/16408

Self-medication Practice among Secondary School Students in Ekiti State, Southwest Nigeria

A. O. Awosusi & P. E. Konwea · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Aims: The aim of this study was to investigate the practice of self-medication and the types of drugs students self-medicate as well as factors influencing practice of self-medication among secondary school students in Ekiti State, Southwest Nigeria. Methods: The study employed a...

Open access Research Article 10.9734/JAMPS/2015/16083

Evaluation of the Physicochemical Properties and Quality Indices of Multisource Tadalafil Drug Products Marketed in Nigeria

Sunday O. Awofisayo, Jolly A. Nnamdi, Jeffry I. Osayande & Magnus A. Iwuagwu · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

The present study evaluates and compares the physicochemical parameters and cost of some multisource tadalafil products marketed in Nigeria. Six randomly selected products were analyzed for weight uniformity, friability, hardness, disintegration, dissolution testing and assay. Th...

Open access Research Article 10.9734/JAMPS/2015/16507

Detection of and Adjustment for Multiple Unmeasured Confounding Variables in Logistic Regression by Bayesian Structural Equation Modeling

Emil Kupek · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Aim: To compare the bias magnitude between logistic regression and Bayesian structural equation modeling (SEM) in a small sample with strong unmeasured confounding from two correlated latent variables. Study Design: Statistical analysis of artificial data. Methodology: Artificial...

Open access Research Article 10.9734/JAMPS/2015/16185

Food Allergens - an Overview on Molecular Properties and Diagnosis

Margarida Valério, Rita Sousa Gomes, Marta Almeida, Ana Margarida Gomes & Ana Margarida Neves · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Food allergy is an increasing and potentially serious problem that can significantly limit patient’s quality of life. The incidence of this disease has been augmenting in recent decades. Classic allergy tests do not reflect the exact immunological reality of allergy. Recently, ma...

Open access Research Article 10.9734/JAMPS/2015/16073

Healthcare-seeking Practices for Common Childhood Illnesses in Northeastern Albania: A Community-based Household Survey

Ditila Doracaj, Edi Grabocka, Elda Hallkaj & Gentian Vyshka · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Introduction: Appropriate medical care-seeking could prevent a significant number of child deaths and complications due to ill health. Objectives: The purpose of our study was to assess care-seeking behaviour of mothers during childhood illnesses and its influencing factors. Meth...

Open access Research Article 10.9734/JAMPS/2015/16088

Investigation of Relaxative Effect of Stem-bark Extract of Erythrophleum suaveolens on rat Phrenic Nerve-diaphragm Muscle

T. O. Ogundeko, I. I. Idyu, M. T. Ojo, V. C. Idyu, E. A. Ogbole, M. I. Builders, M. S. Ramyil, B. O. Toma & A. F. Asalu · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Background: The effect of crude extract of Erythrophleum suaveolens was studied on isolated tissues of the Rat’s phrenic nerve-diaphragm muscles. Study aimed to investigate the relaxant effect of crude extract of E. suaveolens on the skeletal muscle using isolated rat phrenic ner...

Open access Research Article 10.9734/JAMPS/2015/14688

Efficacy of Garcinia kola Seed Ethanolic Extract on Haematological Parameters in Male Wistar Rats

Denen Atsukwei, Eze Ejike Daniel, Samuel Odu Odeh, Moses Dele Adams, Ibrahim Samaila Malgwi & Patricia Chidimma Olih · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

The efficacy of Garcinia kola seed ethanolic extract on selected haematological parameters of male Wistar rats was investigated. Thirty (30) male Wistar rats weighing 150.42±3.98 g were divided into three groups (I, II and III) comprising ten animals each. Animals in group I (con...

Open access Research Article 10.9734/JAMPS/2015/15305

Endodontic Management of Maxillary Canine with Two Canals

Kaustubh Khatod, Ajay Saxena, Manoj Chandak, Aditya Vardhan Patidar & Rama Khatod · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Aim: To report a case of endodontic treatment of a maxillary right canine in which an extra canal was located and successfully treated. Presentation of Case: A 35 year old male reported with pain in maxillary right canine. Pain was dull and intermittent in nature. Instrumentation...

Open access Research Article 10.9734/JAMPS/2015/15276

Agreement between Observers for Pap smear and Visual Inspection Tests in Florianópolis, Southern Brazil

Evandro Russo, Emil Kupek, Joyce Tarnowsky Leitão, João Péricles da Silva Júnior & Maria Beatriz Cacese Shiozawa · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Aim: Despite well established validity and reliability of Pap test, a significant proportion of false negative test results still remains and is partially due to the lack of agreement between observers.  Visual inspection tests (VIT) share this difficulty but their results are im...

Open access Research Article 10.9734/JAMPS/2015/15296

The Efficacy of Intravenous Immunoglobulin in the Treatment of Patients with Acute Disseminated Encephalomyelitis

Iryna Lobanova & Olena Myalovitska · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Background: Acute disseminated encephalomyelitis (ADEM) is a monophaseprocess nevertheless sometimes aggravated by relapses (so-called multiphasecourse of the disease). In such case the treatment must be targeted at reducing clinical manifestations of the disease and prevention o...

Open access Research Article 10.9734/JAMPS/2015/14216