Objective: To investigate the anti-inflammatory activity of the chloroform leaf extract of Palisota hirsuta (CLEPH). Methods: CLEPH was evaluated for anti-inflammatory activity using standard experimental models of inflammation namely: Croton oil-induced mouse ear edema, carragee...
Open access
Research Article10.9734/JAMPS/2015/13813
Aims: Antimullerian hormone (AMH) has been accepted as a marker for the size of the ovarian follicle pool. To interrupt the results of this investigation, age-specific concentrations are needed. The purpose of this study is to compare antimullerian hormone (AMH) concentrations am...
Open access
Research Article10.9734/JAMPS/2015/13883
The effect of various preservatives such as Methyl paraben, Propyl paraben, benzoic acid and Methyl paraben, Propyl paraben (1:10) on a pectin – base ofloxacin vaginal gel was tested. Five batches of pectin-based ofloxacin vaginal gel were assessed by antibiotic sensitive test, d...
Open access
Research Article10.9734/JAMPS/2015/14211
Background: Despite appropriate chelation therapy with desferrioxamine, iron deposition in visceral organs causes tissue damage in thalassemia major patients. Excess iron can generate reactive oxygen species (ROS) that may lead to cell death and apoptosis. Therefore, antioxidants...
Open access
Research Article10.9734/JAMPS/2015/12818
Purpose/Aim of study: We postulate that the timing of phacoemulsification relative to pars plana vitrectomy, internal limiting membrane peel (before, during or after) and gas is an important risk factor for cystoid macular edema. Materials and Methods: We report a retrospective s...
Open access
Research Article10.9734/JAMPS/2015/12865
Aims: To determine O6-Methylguanine in Cancer Patient Blood during Administration of Cyclophosphamide using Ultra High Performance Liquid Chromatography-Tandem Mass Spectrometry. Place and Duration of Study: Dharmais Cancer Hospital and Bioavailability/Bioequivalence Laboratory,...
Open access
Research Article10.9734/JAMPS/2015/12953
Drug release profile and bioavailability indices have been well correlated with the quality of drug products. A comparative evaluation of the quality control parameters and hypoglycaemic drug performance check of some brands of glibenclamide tablets was studied. The physicochemic...
Open access
Research Article10.9734/JAMPS/2015/11206
Aims: The study was aimed at evaluating the hepatoprotective and antioxidant activity of the methanolic extract of C. sieberiana leaves. Study Design: Hepatoprotective, in vitro and in vivo antioxidant activity. Place and Duration of Study: Department of Veterinary Physiology, Ph...
Open access
Research Article10.9734/JAMPS/2015/13443
Aims: To evaluate the antisickling and antibacterial activities of Gardenia ternifolia and Uapaca heudelotii. Study Design: Evaluation of the antisickling and antibacterial activities of anthocyanins and organic acids extracted from Gardenia ternifolia and Uapaca heudelotii In vi...
Open access
Research Article10.9734/JAMPS/2015/13427
Background: Although the assessment of hemostasis is frequently performed during stapling procedures, and is necessary during product development, there is currently no widely-accepted scoring system for its evaluation. In order to better measure stapler performance, we developed...
Open access
Research Article10.9734/JAMPS/2014/11653
Background: Oxidized low-density lipoprotein (OX-LDL) is believed to be a key trigger factor in the genesis of atherosclerosis. It has been postulated that it can activate inflammatory mediators such as high sensitive C-reactive protein (hs-CRP), interleukin 6 (IL6), and tumour n...
Open access
Research Article10.9734/JAMPS/2014/11341
Aims: To evaluate the efficacy of two alkylating structural analogues of chloramphenicol that have potential for application for treatment of dermal sited neoplasms. Study Design: Two compounds have been shown to alkylate guanosine-5’-diphosphate (GDP) at physiological conditions...
Open access
Research Article10.9734/JAMPS/2014/11838
Emeka U. Ejeliogu, Stephen Oguche, Augustine O. Ebonyi, Sylvanus E. Okpe, Esther S. Yiltok, Olukemi Ige, Martha O. Ochoga, Placid Ugoagwu, Christy Dady, Lucy Ogwuche, Oche O. Agbaji & Prosper Okonkwo·Journal of Advances in Medical and Pharmaceutical Sciences·2014
Aims: To determine the incidence and severity of zidovudine-induced anaemia in HIV-infected children initiated on anti-retroviral therapy in Jos, Nigeria. Study Design: This was an observational cohort study. Place and Duration of Study: AIDS Prevention Initiative in Nigeria (API...
Open access
Research Article10.9734/JAMPS/2014/11241