Drug release profile and bioavailability indices have been well correlated with the quality of drug products. A comparative evaluation of the quality control parameters and hypoglycaemic drug performance check of some brands of glibenclamide tablets was studied. The physicochemic...
Open access
Research Article10.9734/JAMPS/2015/11206
Aims: The study was aimed at evaluating the hepatoprotective and antioxidant activity of the methanolic extract of C. sieberiana leaves. Study Design: Hepatoprotective, in vitro and in vivo antioxidant activity. Place and Duration of Study: Department of Veterinary Physiology, Ph...
Open access
Research Article10.9734/JAMPS/2015/13443
Aims: To evaluate the antisickling and antibacterial activities of Gardenia ternifolia and Uapaca heudelotii. Study Design: Evaluation of the antisickling and antibacterial activities of anthocyanins and organic acids extracted from Gardenia ternifolia and Uapaca heudelotii In vi...
Open access
Research Article10.9734/JAMPS/2015/13427
Background: Although the assessment of hemostasis is frequently performed during stapling procedures, and is necessary during product development, there is currently no widely-accepted scoring system for its evaluation. In order to better measure stapler performance, we developed...
Open access
Research Article10.9734/JAMPS/2014/11653
Background: Oxidized low-density lipoprotein (OX-LDL) is believed to be a key trigger factor in the genesis of atherosclerosis. It has been postulated that it can activate inflammatory mediators such as high sensitive C-reactive protein (hs-CRP), interleukin 6 (IL6), and tumour n...
Open access
Research Article10.9734/JAMPS/2014/11341
Aims: To evaluate the efficacy of two alkylating structural analogues of chloramphenicol that have potential for application for treatment of dermal sited neoplasms. Study Design: Two compounds have been shown to alkylate guanosine-5’-diphosphate (GDP) at physiological conditions...
Open access
Research Article10.9734/JAMPS/2014/11838
Emeka U. Ejeliogu, Stephen Oguche, Augustine O. Ebonyi, Sylvanus E. Okpe, Esther S. Yiltok, Olukemi Ige, Martha O. Ochoga, Placid Ugoagwu, Christy Dady, Lucy Ogwuche, Oche O. Agbaji & Prosper Okonkwo·Journal of Advances in Medical and Pharmaceutical Sciences·2014
Aims: To determine the incidence and severity of zidovudine-induced anaemia in HIV-infected children initiated on anti-retroviral therapy in Jos, Nigeria. Study Design: This was an observational cohort study. Place and Duration of Study: AIDS Prevention Initiative in Nigeria (API...
Open access
Research Article10.9734/JAMPS/2014/11241