Isoniazid is an efficacious first line antitubercular drug, though elevations in liver enzymes have been reported. This study evaluated the role of riboceine in modulating isoniazid-induced organ injury in rats. Thirty-five Wistar albino rats of either sex were randomly divided i...
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Research Article10.9734/jamps/2025/v27i9813
Background: The rising burden of hypertension and diabetes in sub-Saharan Africa has intensified the risk of chronic kidney disease (CKD), with body mass index (BMI) playing a critical role in metabolic health. However, limited evidence exists on the sociodemographic and clinical...
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Research Article10.9734/jamps/2025/v27i9812
Background: Leaves of Tamarindus indica have long been used in traditional medicine for managing pain, inflammation, and nervous system disorders. This study aimed to scientifically assess these properties using experimental models in mice. Methods: The aqueous leaf extract of T....
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Research Article10.9734/jamps/2025/v27i8811
The sun emits radiation with different ionising energies in a wide spectrum of wavelengths, frequencies and energies inflicting various forms of actinic damage to dermal structures. Damage can either be direct DNA damage through alteration of gene expression and compromised infla...
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Research Article10.9734/jamps/2025/v27i8810
Background: Smoking remains a significant global health concern that results in millions of deaths annually. Despite its widely known health consequences, smoking remains highly prevalent among young adults, including university students. This study investigates smoking behavior,...
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Research Article10.9734/jamps/2025/v27i8809
Aims and Objectives: To evaluate the sedentary behaviours of the staff of UBTH and educate them toward compliance with the global recommendations by the WHO. To also measure their level of physical activity and compare it with the global recommended standards of 150-300 minutes p...
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Research Article10.9734/jamps/2025/v27i8807
Plant-drug interactions mediated by cytochrome P450 (CYP450) enzymes are a critical area of study owing to their potential to alter drug metabolism, efficacy, and toxicity. This review examines how common phytochemicals such as flavonoids, polyphenols, alkaloids, and terpenes mod...
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Research Article10.9734/jamps/2025/v27i8808
Aims and Objectives: This review aims to provide a comprehensive overview of risk factors, biomarkers, pathophysiology, and synthesis of experimental models of Parkinson’s Disease (PD), with an emphasis on their mechanisms and translational models. Materials and Methods: A narrat...
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Research Article10.9734/jamps/2025/v27i8806
Background: Despite growing evidence that exogenous factors such as environmental conditions, influence the clinical severity of sickle cell anemia, their impact remain poorly understood in Cameroon. This study explores clinical clusters of sickle cell anemia and their associatio...
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Research Article10.9734/jamps/2025/v27i7805
Stanley Ebiogbo Ozori, Obilahi-Abhulimem Thomas Julius, Kalada Godson McFubara, Mbah Kanayochukwu Michael, Atemie Gordon, Usman Malgwi Justina & Warisuo Ariwelo Solomon·Journal of Advances in Medical and Pharmaceutical Sciences·2025
Background: This study was aimed at evaluating the safety of adjunctive sublingual misoprostol in reducing intraoperative blood loss during caesarean section, with the objectives of determining the need for additional intraoperative oxytocic, need for postoperative blood transfus...
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Research Article10.9734/jamps/2025/v27i7804
This study aims After a period of 14 days of acclimatization, twenty (20) healthy male albino rats were randomly allocated to four groups, control group(takes water only), low dose group (2.5mg/kg bw of tadalafil), medium dose group (5 mg/kg. b.w of tadalafil) and high dose group...
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Research Article10.9734/jamps/2025/v27i7803
Background: A thyroid incidentaloma (TI) is an unexpected, asymptomatic thyroid lesion inadvertently discovered during an investigation of an unrelated condition. Although most TIs are benign, there is a significant potential for malignancy. The prevalence of TI is increasing due...
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Research Article10.9734/jamps/2025/v27i7802
Acne Vulgaris offers an in-depth analysis of acne vulgaris, addressing its underlying pathophysiology, clinical presentation, and available treatment modalities, with particular emphasis on both conventional pharmacologic therapies and emerging natural alternatives. Acne vulgaris...
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Research Article10.9734/jamps/2025/v27i7801
This article presents a comprehensive imaging review of ovarian mass mimics, emphasizing the differential diagnosis of extra-ovarian lesions in the female pelvis. It highlights the importance of anatomical landmarks and specific imaging signs such as the beak sign and the ovarian...
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Research Article10.9734/jamps/2025/v27i7800
Introduction: Pulmonary fibrosis (PF) is a progressive lung disorder marked by excessive collagen accumulation and tissue remodeling, commonly associated with aging and oxidative stress. Goji berry (Lycium barbarum), a natural source of bioactive compounds such as Lycium barbarum...
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Research Article10.9734/jamps/2025/v27i7799