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All published articles 892

Innovative Superdisintegrant Strategy for the Formulation of Rapidly Disintegrating Lamotrigine Tablets

Ramakrishnasai N, Sharath T P, Narahari K V, Naga mownica K P, Lakshmi Priya N S, Shrikrishna M Naik & Sagar M · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Aims: Lamotrigine (LMG) is a poorly water-soluble antiepileptic drug (0.17 mg/mL at 25°C), commonly prescribed for epilepsy, including secondary generalized tonic-clonic seizures, as well as simple and complex partial seizures. Due to its low solubility and swallowing difficulty...

Open access Research Article 10.9734/jamps/2025/v27i5783

School Health Program: Early Detection and Environmental Health Assessment of Children and Adolescents in National Guard Iskan, Alhassa

Abdulrahman Alarfaj, Mounther AlNaim, Ahmed Alhashim, Mohamed Al-Falah, Abdulaziz Alyousof, Saleh Almulhim, Munerah Alhumaidy & Ibrahim Albakheet · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Background: The health and well-being of school students are critical for future generations. In Saudi Arabia, the School Health Program aims to enhance student health through early detection of health issues and evaluation of school environments. This study assessed the general...

Open access Research Article 10.9734/jamps/2025/v27i5782

Evaluation of a Cell-Based Anti-Mosquito Vaccine Derived from Malpighian Tubules of Culex Mosquitoes in a Mouse Model

Mst. Sakila Jahan, Sharmin Mustari, Md. Naymur Rahman, Sadia Islam Reya, Moni Krishno Mohanta, Md. Ariful Hasan & Md Fazlul Haque · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Mosquitoes are vectors for several deadly diseases such as dengue, malaria, filariasis, yellow fever, and Zika, contributing significantly to global mortality. Current control methods such as physical, chemical, and biological control are costly, often ineffective, and can pose r...

Open access Research Article 10.9734/jamps/2025/v27i5780

Bechet’s Disease in Absence of Oral Aphthosis: Utility of Updated Criteria

C. Sollah, M. Moudatir, L. Barakat, M. Benzakour, K. Echchilali, S. Mourabit & H. Elkabli · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Background : Behçet disease (BD) is a chronic, relapsing, systemic vasculitis of unknown etiology with the clinical features of oral and genital ulcers, cutaneous vasculitic lesions, ocular, articular, vascular, gastrointestinal, neurologic, urogenital and cardiac involvement. Mu...

Open access Research Article 10.9734/jamps/2025/v27i5781

Implementation of a 100% Drug Prescription Fill Policy at the University of Benin Teaching Hospital, Nigeria: The Role of Effective Stakeholder Engagement and Patronage

Okuoimose Jacob Egharevba · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Aims and Objectives: To ascertain the effects, mode of participation of policy actors and evaluation of the influence of the patronage factors on the UBTH pharmacies in the implementation of the 100% drug prescription fill policy in the Hospital. Background: Effective stakeholder...

Open access Research Article 10.9734/jamps/2025/v27i5779

Development and Evaluation of Polymeric Film Forming Solution of Ciclopirox Olamine for Topical Fungal Therapy

Shashank S Bhardi, Vidhyashree B, Arvinder Kaur & Preethi G B · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Aim: Formulation and assessment of polymeric film forming solution (PFFS) loaded with Ciclopirox olamine (CPO) for managing topical fungal infections. Methods: PFFS was prepared using a common solvent method with a range of polymers, such as Eudragit RL 100, Eudragit RS 100, PVP...

Open access Research Article 10.9734/jamps/2025/v27i5778

Physicians’ Knowledge, Attitudes, and Practices in Gout Management: A Cross-sectional Study at Soba Teaching Hospital

Maab M. Taha, Mazin S. Matar, Elkhanssa Abdelhameed Ahmed Elhag, Riham M. Hamadouk, Kannan O. Ahmed & Bashir A. Yousef · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Background: Gout is a disease caused by an overload of uric acid in the body, which leads to the formation of urate crystals that deposit in tissues, particularly in the joints. The deposition of these crystals causes recurring episodes of joint inflammation. This study aims to e...

Open access Research Article 10.9734/jamps/2025/v27i5777

Unleashing the Potential of Spanlastics as Drug Delivery Carrier

Lakshmi Priya N S, Shivakumar Hagalavadi Nanjappa, Narahari K V, Arpitha Nandakumar, Sharath T P & Yashwanth S · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Spanlastics, a novel class of vesicular drug delivery systems, have garnered significant attention for their potential to overcome the limitations of traditional drug administration. Comprising non-ionic surfactants and edge activators, spanlastics exhibit unique characteristics...

Open access Research Article 10.9734/jamps/2025/v27i5776

Oral Wafer Technology: Revolutionizing Drug Delivery for Enhanced Patient Compliance and Bioavailability of Specific Low Dose Drug Categories

Arpitha Nandakumar, Shivakumar Hagalavadi Nanjappa, Lakshmi Priya N S & Yashwanth S · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Oral wafer technology has emerged as a significant innovation in pharmaceutical drug delivery, offering enhanced therapeutic efficacy, patient compliance, and ease of administration compared to conventional dosage forms. These thin, rapidly dissolving films eliminate the need for...

Open access Research Article 10.9734/jamps/2025/v27i5775

Anticonvulsant and Antidepressant Effects of Daniellia oliveri (Rolfe) Hutch and Dalz Aqueous Extract in Pilocarpine Model of Temporal Lobe Epilepsy in Mice

Jean-Jacques Kodji Midala, Njapdounke Kameni Jacqueline Stéphanie, Ngo Ngimout Kidjama, Joseph Ngaibi, Wangbara alkali tchang, Bigued, Lamare Tchachoua Adrien, Vanessa Tita Jugha, Germain Sotoing Taiwe & Ngo Bum Elisabeth · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

In temporal lobe epilepsy, an average of 30% suffer from depression.The objective of this study is to evaluate the anticonvulsant and antidepressant effects of Daniellia oliveri in pilocarpine model of temporal lobe epilepsy. the experiment lasted 7 days.Muss musculus Swiss mice...

Open access Research Article 10.9734/jamps/2025/v27i4773

The Phytochemical Profile of Sansevieria Roxburghiana: A Key to Unlocking Its Therapeutic Applications

Madhavi Pillalamarri, Snehalatha Vaddemani, Mahathi Pasumarti, Tharun Madhurna, Devaki Pasupula & Siddhartha Lolla · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Aim: This study examines the potential of plant analgesics as an analgesic measure concerning their safety, efficacy and affordability over conventional synthetic analgesics. Study Design: This is a review article addressing the classification of pain, the action of analgesic mec...

Open access Research Article 10.9734/jamps/2025/v27i5774

Anticonvulsant and Anti-amnesic Effects of an Aqueous Extract of Crassocephalum bauchiense (Hutch.) Milne-Redh. (Asteraceae) in Mice Pilocarpine Model of Temporal Lobe Epilepsy

Tchang Alkali Wangbara, Jacqueline Stephanie Kameni Njapdounke, Ngo Ngimout Kidjama, Bigued, Jean-Jacques Kodji Midala, Joseph Ngaibi, Lamare Tchachoua Adrien, Vanessa Tita Jugha, Germain Sotoing Taiwe & Elisabeth Ngo Bum · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

This study aimed to investigate the anticonvulsant and anti-amnesic effects of Crassocephalum bauchiense aqueous extract in pilocarpine model of temporal lobe epilepsy. Mice were treated for seven consecutive days as follows: one normal group and one negative control group that r...

Open access Research Article 10.9734/jamps/2025/v27i4771

Assessing the Feasibility and Sustainability of a 100% Drug Prescription-fill Policy at the University of Benin Teaching Hospital, Nigeria: Implications for National Health and Drug Policies

Okuoimose Jacob Egharevba, Abdulrauf Ambali, S.E Aghahowa & Thaddeus Aichienede · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Aims: To determine the feasibility and sustainability of the 100% drug prescription-fill policy goals and compare its achievements with the alternate policy in fulfilling the national Health policies. Study Design: The study was limited to staff who are five years and above in th...

Open access Research Article 10.9734/jamps/2025/v27i4770

Ethical and Regulatory Challenges for Contract Research Organizations Conducting (Outsourced) Clinical Research in Sub-Saharan Africa with a Case Study of Cameroon

Charles Ntungwen Fokunang, Estella Achick Tembe-Fokunang, Marceline Djuidje Ngounou, Basile Ngono, Innocente Mantsana, Pasteur Sap Jacques Duclaire, Mgr Etoundi Jean, Mpah Wanga Julien Eymard, Mfochive Njindam Illiasou, Christie Tiwoda, Francis Ndongo Ateba, Tchinda Tiabou, Lowe Gnintedem Patrick, Eboumbou Moukoko Caroline Else, Ngu Paul Nembo, Jerome Ateudjio, Charles Kouanfack, Leopold Lehman, Binan Fidele Ange, Marie Claire Assoumou Okomo, Mbacham Fon Wilfred & Vincent Pryde Kehdingha Titanji · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Introduction: Contract Research Organizations (CROs), Clinical Research Centers/Networks and private research institutions play an important role in the clinical research process, especially in the drug discovery and development process. They act as essential partners for pharmac...

Open access Research Article 10.9734/jamps/2025/v27i4768

Exercise Mediated Prevention of Cognitive Decline

Zain Jandial, Ashvin Kumar & Greg Whyte · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Decline in cognitive functions and behavioural problems are the common and inter-related symptoms of dementia. Progression of behavioural problems in people with dementia is associated with a higher rate of cognitive decline. Cognitive and behavioural problems can induce diverse...

Open access Research Article 10.9734/jamps/2025/v27i4769