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All published articles 175

Effects of Medicinal Plants on Urinary Incontinence: A Systematic Review

Mahnaz Yavangi & Saeid Heidari-Soureshjani · Journal of Pharmaceutical Research International · 2018

Urinary incontinence is one of the disorders that may develop for various reasons, affect different aspects of life, and declining quality of life. Relevant key terms were used to retrieve the articles published between 2000 and 2018 and indexed in the Institute for Scientific In...

Open access Research Article 10.9734/JPRI/2018/39691

Investigation of Phenolic Content, Antioxidant Capacities, Anthelmintic and Cytotoxic Activities of Thymus zygioides Griseb.

Arzu Kaska, Mehmet Çiçek, Nahide Deniz & Ramazan Mammadov · Journal of Pharmaceutical Research International · 2018

Aims: This study was designed to evaluate the total phenolic, flavonoid content and antioxidant properties of various extracts (ethanol, methanol, acetone, water) of Thymus zygioides and the ethanol extract was also investigated for phenolic components, anthelmintic and cytotoxic...

Open access Research Article 10.9734/JPRI/2018/39688

Role of Toxins of Uropathogenic Escherichia coli in Development of Urinary Tract Infection

Saber Soltani, Amir Darb Emamie, Mahsa Dastranj, Abbas Farahani, Abolfazl Davoodabadi & Parviz Mohajeri · Journal of Pharmaceutical Research International · 2018

Three clinical syndromes including diarrhea/enteritis, urinary tract infection and septicemia/meningitis can be found as a result of infection with each of the E. coli pathotypes. Uropathogenic Escherichia coli toxins are one of the most important factors in the spread of these i...

Open access Research Article 10.9734/JPRI/2018/39188

Self-Medication with Analgesics: Knowledge and Attitudes of Senior Medical Students and Interns at King Abdulaziz University, Jeddah, Saudi Arabia

Nahla Khamis Ibrahim & Banan Mohamed Alamoudi · Journal of Pharmaceutical Research International · 2018

Aim: The study was conducted to assess the knowledge and attitudes of clinical years’ medical students and interns towards self-medications with analgesics, King Abdulaziz University (KAU), Jeddah, Saudi Arabia. Methodology: A cross-sectional study design was conducted among seni...

Open access Research Article 10.9734/JPRI/2018/39245

Synthesis and Ca2+-desensitizing Activity of 2-methyl-7-aryl(α-furyl)-[1,3]thiazolo[4,5-d]pyridazin-4(5H)-ones

Anatoly Soloviev, Sergey Demchenko, Ludmyla Bobkova, Valentyn Panchenko, Sergey Zelenskyi & Anatoly Demchenko · Journal of Pharmaceutical Research International · 2018

Aims: Search of new chemical compounds for pressure decrease in accordance with new mode of action. Study Design: Novel 2-methyl-7-aryl(α-furyl)-[1,3]thiazolo[4,5-d]pyridazin-4(5H)-ones were synthesized in 67-84% yields via reaction of 2-methyl-5-benzoyl(furoyl)-thiazol-4-carboxy...

Open access Research Article 10.9734/JPRI/2018/37338

Molecular Typing and Antimicrobial Susceptibility of Acinetobacter baumannii Isolates in Kermanshah City with Pulse Field Gel Electrophoresis (PFGE)

Parviz Mohajeri, Touraj Esmailzadeh, Sara Torkaman & Abbas Farahani · Journal of Pharmaceutical Research International · 2018

Background and Objective: Acinetobacter baumannii (A. baumannii) in the last decade has been identified as one of the opportunistic pathogens and an important cause of nosocomial infections. Molecular typing plays an important role in studying the epidemiology of Acinetobacter. T...

Open access Research Article 10.9734/JPRI/2017/39168

In vitro Proliferation and Wound Healing Effects of Narcissus tazetta L. Bulb on Primary Human Dermal Fibroblasts

Maryam Rameshk, Fariba Sharififar, Mitra Mehrabani, Abbas Pardakhty & Alireza Farsinejad · Journal of Pharmaceutical Research International · 2018

Aims: Narcissus tazetta L. bulbs have been used in Traditional Persian medicine (TPM), as "Zaroor" for wound healing. Toward quality assurance of the plant, pharmacognostic and phytochemical studies, physicochemical characterization, and healing effects of "Zaroor" were studied....

Open access Research Article 10.9734/JPRI/2017/39090

Effect of Resveratrol on Liver Histopathology of Lead-induced Toxicity in Wistar Rats

Salisu Muhammad Highab, Musa Aliyu & Bala Yauri Muhammad · Journal of Pharmaceutical Research International · 2018

Aims: To investigate the effect of resveratrol on liver histopathology of lead-induced toxicity in wistar rats. Study Design: Experimental Study. Place and Duration of Study: Department of  Pharmacology and  Therapeutics, Ahmadu Bello University, Zaria (11° 10' N, 07° 38' E), at...

Open access Research Article 10.9734/JPRI/2017/23253

Antioxidant and Anti-urease Activity of Various Solvent Extracts of “Terminalia arjuna” Seeds

Naila Aslam, Mahmood Ahmad, Kashif Barkat & Muhammad Khawar Abbas · Journal of Pharmaceutical Research International · 2018

Background: Terminalia arjuna, a popular cardio curative plant. Present work emphasizes on the evaluation of antioxidant and anti-urease activity of different fractions extracts of Terminalia arjuna seeds. Methods: Six alternate fractions including methanol, ethanol, n- butanol,...

Open access Research Article 10.9734/JPRI/2017/38794

Application of Molecular Techniques in Quality Control of Drugs of Natural Origin; A Review

Juwairiya Butt, Shumaila Arshad, Zulfiqar Ali Mir, Sophia Awais, Javed Iqbal & Saeed-Ul-Hassan . · Journal of Pharmaceutical Research International · 2018

Pharmacognosy is a long established pharmaceutical science, which played a diverse role in the discovery, characterization, production and standardization of drugs. Molecular pharmacognosy using molecular biological tools has extended the scope of pharmacognostical science and pl...

Open access Research Article 10.9734/JPRI/2017/38523

A Review on Tablet Scoring: Background, History and Current Regulatory Considerations

Maitri R. Trivedi, Hardikkumar H. Patel & Rutesh H. Dave · Journal of Pharmaceutical Research International · 2018

Tablet splitting or breaking of tablets into multiple strengths has been a common practice across the world. Splitting of tablet offers various advantages such as dose flexibility and ease of swallowing in different population including geriatric and pediatric patients (wide pati...

Open access Research Article 10.9734/JPRI/2017/39027

Ciprofloxacin Antibiotics Removal from Effluent Using Heat-acid Activated Red Mud

Davoud Balarak, Ali Joghataei, Ferdos Kord Mostafapour & Edris Bazrafshan · Journal of Pharmaceutical Research International · 2018

In this study, the adsorption of Ciprofloxacin (CIP) antibiotics from a synthetic solution containing CIP is investigated using Red Mud (RM) and Red Mud that is activated by HCL (ARM). Scanning Electron Microscopy (SEM) techniques are used to morphological characteristics of Red...

Open access Research Article 10.9734/JPRI/2017/38974

Investigations into Antibacterial, Phytochemical and Antioxidant Properties of Vitellaria paradoxa (Gaertn.) Stem Bark Extracts

Oluwaseun Oyetunji Olasunkanmi, David Ayinde Akinpelu, Paul Opeyemi Adeniyi, Oludare Femi Ajayi, Joseph Omololu-Aso & Felix Oluwasola Olorunmola · Journal of Pharmaceutical Research International · 2018

This study investigated the antibacterial potentials and mechanisms of action of crude extract and fractions from stem bark of Vitellaria paradoxa on susceptible bacterial isolates. It also assessed the phytochemical constituents and antioxidant properties of the plant. This was...

Open access Research Article 10.9734/JPRI/2017/38749

Screening and Production of Peptidase Producing Bacillus Species Isolated from Soil

Shahpara Rehman, Rimsha Khan, Syed Bilal Hussain & Syed Aun Muhammad · Journal of Pharmaceutical Research International · 2018

Aims: Proteases are the most deliberate microbial enzyme at mercantile, industrial, health professional, analytic, symptomatic, outgoing interruption and other sectors. Methodology: About 8 isolates were recovered from different soil samples gathered from various fields of Abdul...

Open access Research Article 10.9734/JPRI/2017/37048

Molecular Characterization Using gtf Gene Detection and Medium Optimization of Beta-D-Glucan Production from Pediococcus parvulus F1030 Isolated from Local Egyptian Boza

Khalid Abd El Ghany, Ragaa A. Hamouda, Hoda A. Mahrous, Sherin M. A. Sharaf & Hanafy A. Hamza · Journal of Pharmaceutical Research International · 2018

Background: Lactic acid bacteria (LAB) have great benefits which can improve the nutritional value of food, reduces some infections, immune modulator effect, curbs some types of cancer and restricts glucose level of serum. Aims: This study was carried out to detect glycosyltransf...

Open access Research Article 10.9734/JPRI/2017/39079