Objective: To investigate the antifungal, antioxidant and phytochemical screening of Melia azedarach flowers by using different solvents. Materials and Methods: Antifungal activity was experimented against three fungi (Aspergillus niger, Aspergillus fumigatus, Aspergillus flavus)...
Open access
Research Article10.9734/JPRI/2017/38246
Aim: This study used QSAR Pharmacophore-based virtual screening and molecular docking to identify lead compounds and determine structural requirements for breast cancer inhibitor development. CoMFA and CoMSIA modeling was employed to design more potential inhibitors. Materials an...
Open access
Research Article10.9734/JPRI/2017/37821
Aim: This study was designed to investigate the bioactive spice to determine its activity against some selected human bacterial pathogens. The spice studied was Ocimum gratissimum (clove basil). Place and Duration of study: Microbiology laboratory of Bells University of Technolog...
Open access
Research Article10.9734/JPRI/2017/37897
Aim and Objectives: To design, formulate and perform in vitro studies of a fixed dose combination (FDC) immediate release solid dosage form of the antihypertensive drugs atenolol, enalapril and hydrochlorothiazide. The objectives of the study were to perform pre-formulation studi...
Open access
Research Article10.9734/JPRI/2017/38019
The present studies evaluate rheological properties and in-vitro permeability properties of Escitalopram Oxalate (ECO) containing hydroxypropyl cellulose (Klucel HF, HPC) gels prepared with different carbon chain length containing fatty acids. The formulations were prepared by mi...
Open access
Research Article10.9734/JPRI/2017/37901
Abudukadeer Kuerban, Said S. Moselhy, Hanaa Ghashlan, Taha A. Kumosani, Othman A. S. Baothman, Mustafa Zeyadi, Nawal Helmi, Tahani M. Alghamdi, Mazin A. Zamzami, Muqtadir Baig Mirza, Fareeduddin Quadri Syed, Furkhan Ahmed Mohammed, Abdulrahman L. AL-Malki & Khalid O. Abulnaja·Journal of Pharmaceutical Research International·2017
Aims: Bioactive peptides are acknowledged for their vital contributions to health promotion. This study aims to evaluate antiglycation, antioxidant and antiproliferative ability of peptides derived from tryptic hydrolysis of Soya bean. Place and Duration of Study: Department of B...
Open access
Research Article10.9734/JPRI/2017/37636
Background: Pharmaceutical care model (PCM) is the philosophy of practice that includes identifying and resolving medication therapy problems to improve patient outcomes. Patient counseling by a pharmacist is a fundamental step in health care practice, as it allows the patients t...
Open access
Research Article10.9734/JPRI/2017/37705
The medicinal plants have been known for their wide variety of applications for centuries. R. hastatus and R. himalyica are such medicinal plants which have been used in Ayurveda for their excellent antioxidative and scavenging properties. The present study is designed to explore...
Open access
Research Article10.9734/JPRI/2017/37143
Background: Abelmoschus esculentus L. or okra is a vegetable of Malvaceae family. Aim: Okra seeds were dried at 60°C, ground, and extracted by using absolute ethanol. The acquired extract was investigated for chemical constituents, cytotoxicity, anti-tyrosinase activity, and anti...
Open access
Research Article10.9734/JPRI/2017/37587
The study investigated the spoilage bacteria associated with selected body lotions commonly used amongst students of the University of Port Harcourt. The influence of the body lotion on the bacterial composition of the skin was also determined. Five in- use lotions were obtained...
Open access
Research Article10.9734/JPRI/2017/33478
The aim of this research work was to formulate and systematically evaluate in vitro performance of extended release matrix tablets of Losartan potassium. Tablets were prepared by direct compression method, applying Response Surface Methodology (RSM) by incorporating a 3-factor, 2...
Open access
Research Article10.9734/JPRI/2017/36668
Aim of the Study: This study aims to highlight the factors that contribute to less job satisfaction for pharmacists, working in private community pharmacies in Eastern region of Saudi Arabia. Material and Methods: A self-administered survey was distributed among pharmacist using...
Open access
Research Article10.9734/JPRI/2017/37704
Md. Nasrullah, Anamul Haque, Saeed Ahmed Alzahrani, Mohammad Ashraf Uddin, Zerina Yasmin, Md. Sahab Uddin, Yaaser Q. Almulaiky & Abudukadeer Kuerban·Journal of Pharmaceutical Research International·2017
Aims: Alangium salviifolium (L. f.) Wang is a medicinal plant of the Alanginaceae family which was used as a traditional medicine to cure or prevent a variety of ailments. The aim of the study was to investigate the anticholinesterase effects and compare the phytochemical and ant...
Open access
Research Article10.9734/JPRI/2017/37887
Objective: This study aims to analyze the perceived responses from physicians and patients towards an alternative drug suggested by pharmacist in a physician prescription and to observe the reasons for rejection from physicians as well as patients. Methods: A cross sectional stud...
Open access
Research Article10.9734/JPRI/2017/37706
Ali Ghorbani-Abdehgah, Mehdi Jafari, Behnam Molavi, Abolfazl Shojaiefard, Shirzad Nasiri, Aidin Yaghoobi Notash Jr, Ali Mir & Ahmadreza Soroush·Journal of Pharmaceutical Research International·2017
Background: Postoperative pain management is an important issue to increase the quality of laparoscopic procedures. In this study the effects of Bupivacaine injection in ports of laparoscopic cholecystectomy and adjunction site of liver and gall bladder was determined on postoper...
Open access
Research Article10.9734/JPRI/2017/36222