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All published articles 579

Cryptorchidism: A 20-Year Journey of Patient Outcomes and Family Concerns – A Cohort Study at a Single Center

Mohammed J Aboud · Asian Journal of Pediatric Research · 2024

Background: Undescended testis (UDT), or cryptorchidism, is a prevalent pediatric condition with significant implications for fertility and malignancy risk if untreated. Affecting 1–5% of male infants, UDT is influenced by genetic, hormonal, and environmental factors. Methods:  T...

Open access Research Article 10.9734/ajpr/2024/v14i12409

The Role of Synaptic Cargo Transporters in Regulating Neuronal Excitation/Inhibition Balance in Autism Spectrum Disorders: A Focus on Syntabulin-syntaxin 1 A/B Axis

Stefan Bittmann · Asian Journal of Pediatric Research · 2024

Various cargo vesicles containing presynaptic proteins are transported from the neuronal cell body to the neuronal terminal to aid in active zone formation. Researchers showed altered levels up to 25 different synaptic proteins (SNAP47, GRIA3/4, GAP43, synaptotagmin 2, LRFN2, SV2...

Open access Research Article 10.9734/ajpr/2024/v14i12408

Evaluating the Effectiveness and Coverage of Vaccination Programs in Reducing the Incidence of Paediatric Infectious Diseases

Thana Sarkis Karaut · Asian Journal of Pediatric Research · 2024

Background: Pediatric infectious diseases pose a significant risk to child health worldwide. Vaccination programs have greatly reduced the incidence and severity of these diseases, though coverage and efficacy differ across regions. This mini-review examines how effectively these...

Open access Research Article 10.9734/ajpr/2024/v14i12407

Effectiveness of Roux-en-Y Hepaticojejunostomy in Reversing the Liver Histological Changes in Patients Presenting Symptomatically and Asymptomatically with Type I & IV Choledochal Cyst

Dayal Chandra Mohanta, AKM Zahid Hossain, Md. Rezaul Karim Mojumder, ASM Arifuzzaman, Mahabub Hossain, Dizen Chandra Barman & Md. Shahinur Rahman · Asian Journal of Pediatric Research · 2024

Purpose: Choledochal cyst, a cystic dilatation of biliary tree, is a congenital abnormality of unknown etiology. Excision of cyst & biliary reconstruction is the mainstay of treatment. Most patients (80%) with choledochal cyst are detected after clinical manifestations. Major...

Open access Research Article 10.9734/ajpr/2024/v14i12405

Type 1 Diabetes (T1D) in Children under 5 Years of Age: Multicentric Study of 22 Cases

Djibril Boiro, Aminata Mbaye, Amadou Sow, Babacar Niang, Aliou Abdoulaye Ndongo, Fatou Adama Fall, Ndiogou Seck, Idrissa Basse, Ndeye Fatou Sow & Modou Gueye · Asian Journal of Pediatric Research · 2024

Introduction: The incidence of T1D is increasing worldwide, particularly in young children under 6 years of age. The objective of this study was to describe the characteristics of type 1 diabetes in children under 5 years of age in our resource-limited country setting. Materials...

Open access Research Article 10.9734/ajpr/2024/v14i12404

Predictors of Postnatal Care Utilization among Postnatal Mothers: A Community-based Cross-sectional Study in Northern Ghana

Balkisu Seidu, Nasara H. Yakubu, Felicia B. Basoglee, Gifty J. Sumani, Bawa K. Khadija, Mina Sapio, Emelia Boateng, Ayishetu Sango, Dorithy T. Angakumpo, Delilah Nonterah, Rashida Atrime, Zeinab Abubakari, Mohammed A. Kojo, Rashida A. Goribia & Sumani Yakubu · Asian Journal of Pediatric Research · 2024

Introduction: Postnatal care (PNC) is crucial for both mothers and newborns, reducing maternal and neonatal fatalities. It is essential for mitigating physical and cognitive impairments, disability, and mortality. However, it is often underutilized for delivering high-quality ser...

Open access Research Article 10.9734/ajpr/2024/v14i11402

Disseminated Lupus Erythematosus: Neurological Manifestations in Childhood: A Case Series of Two Patients

R. Icharmouhene, A. Guenoun, N. Oulhyan, N. Mabrouk, H. Aitoumar & B. Chkirat · Asian Journal of Pediatric Research · 2024

Neuropsychiatric lupus encompasses the neurological and psychiatric manifestations of  systemic lupus erythematosus and presents a significant diagnostic challenge due to its broad clinical variability. Affecting between 14% and 75% of lupus patients, it can occur at any stage of...

Open access Research Article 10.9734/ajpr/2024/v14i11401

Epidemiological, Clinical and Biological Aspects of Childhood HIV in Libreville

Midili T L, Eyi Zang C, Lembet Mikolo A M, Mekame Méyé A E P, Mintsa Mi Nkama E J, Mayombo Moutsatsa J, Koumba Maniaga R, Loembe F C, Kiba G L, Mabery Grondet A, Manga Koumba A, Kuissi Kaimgang E & Ategbo S · Asian Journal of Pediatric Research · 2024

Introduction: Human immunodeficiency virus (HIV) infection is a chronic viral infection characterized by the progressive destruction of CD4 T lymphocytes. Its prevalence in Gabon is estimated 4.1% with approximately 2,500 affected children. This pathology remains a real public he...

Open access Research Article 10.9734/ajpr/2024/v14i11400

A Case Report on Anti-N-Methyl-D-Aspartate Encephalitis

Sowndharya S & John Felix S N · Asian Journal of Pediatric Research · 2024

Aim: The case study aims to describe and evaluate the initial neuropsychiatric symptoms, therapeutic methods, and diagnostic criteria, of a 3-year-old girl who had been diagnosed with anti-N-Methyl-D-Aspartate Receptor (NMDAR) encephalitis. This case study implies the importance...

Open access Research Article 10.9734/ajpr/2024/v14i11399

Poisoning with Local Anesthetics Following Circumcision : A Case Report

Midili T L, Mintsa-Mi-Nkama E, Mekame Meye A E, Loembe F C, Lembet Mikolo A M, Mabery Grodet A, Kiba L, Patipe V, Kuissi Kamgaing E & Ategbo S · Asian Journal of Pediatric Research · 2024

Introduction: Circumcision or posthectomy is the removal of the foreskin, this act seems commonplace practiced by paramedical personnel or unqualified traditional practitioners who may cause significant complications. Objective: Our work aimed to highlight one of the complication...

Open access Research Article 10.9734/ajpr/2024/v14i11398

Associated Factors of Low Birth Weight among Newborns at Hospitals in Kisangani, Democratic Republic of Congo

Anzani Malongo, Komanda Likwekwe Isaac, Gelengi Mbongo, Balimo Limbele, Ekili Molisho, Melangana Menama, Botela Ponea, Ramazani Tabora, Kalafulu Imurani, Boseleka Bokumbuangole, Bokanga Ekelenge, Issa Yakusu, Tshingombo Muyaya Trydon & Ossinga Bassandja · Asian Journal of Pediatric Research · 2024

Background: Low birth weight remains a major public health problem in every country in the world. It is a predictor of early neonatal mortality, morbidity and long-term health. The aim of this study was to determine the prevalence of low birth weight and to identify the associate...

Open access Research Article 10.9734/ajpr/2024/v14i11397

Progress in the Treatment of Tourette Syndrome

Wenyan Jiao, Muhammetaly Agamedov, Guvanch Kerimov, Jiaru Zheng, Stefan Bittmann, Begench Annaye & Fuyong Jiao · Asian Journal of Pediatric Research · 2024

Tourette Syndrome, a persistent neuropsychiatric condition predominantly encountered in childhood, significantly influences an individual's behavior, social engagement, and daily life activities. Current therapeutic strategies for managing Tourette Syndrome can broadly be classif...

Open access Research Article 10.9734/ajpr/2024/v14i10395