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All published articles 781

Systematic Review and Meta-Analysis of Hibiscus sabdariffa in Hypertension Management

Raphael Nyarkotey Obu · Journal of Complementary and Alternative Medical Research · 2025

This study systematically reviews and meta-analyzes existing evidence on the efficacy of Hibiscus sabdariffa in managing high blood pressure. A comprehensive search of databases, including PubMed, Scopus, and Web of Science, identified randomized controlled trials and observation...

Open access Research Article 10.9734/jocamr/2025/v26i1613

Protective Effects of Flavonoids-rich and Saponins-rich Extracts from Tiger Nuts and Date Fruits on Prostate Histoarchitechture in Aluminum-exposed Wistar Rats

Agaba, Eric Agim, Ujah, Williams Oche, Enang, Kingsley Bassey, Fischer, Victor A, Emmanuel I. Odom & Adie, Christopher Utsu · Journal of Complementary and Alternative Medical Research · 2025

Aim: To evaluate the histological effects of flavonoid and saponin fractions from Cyperus esculentus (tiger nuts) and Phoenix dactylifera (date fruits) on the prostate gland of Wistar rats exposed to aluminum chloride, focusing on their potential protective properties against alu...

Open access Research Article 10.9734/jocamr/2025/v26i1610

Histopathological Study of Subacute Administration of Saccharum officinarum Leaf Extract on Some Organs of Rat

Jude E. Okokon, John A. Udobang, Chinyelu C. Osigwe, Uwaeme Ugonma Florence, Uduak P. Ise & Utibe A. Edem · Journal of Complementary and Alternative Medical Research · 2025

The leaves of Saccharum officinarum (Family-Poaceae) is employed traditionally for ethnotherapy of malaria and fever among others. Evaluation of subacute administration of Saccharum officinarum leaf extract for possible effect on organs of rats was carried out. The leaf extract (...

Open access Research Article 10.9734/jocamr/2025/v26i1611

Community Perceptions of Traditional and Pharmaceutical Hypertension Treatments in Vryman’s Erven, Berbice, Guyana

Obena Vanlewin, Andrew Hutson, Karishma Jeeboo, Bibi Ally-Charles, Charlan Abrams & Cecil Boston · Journal of Complementary and Alternative Medical Research · 2024

This study explores the integration of traditional and pharmaceutical remedies in managing hypertension in the rural Berbice community (Vryman’s Erven), New Amsterdam, Guyana. Expanding the use of these remedies means evaluating their effectiveness, relevance to the culture, and...

Open access Research Article 10.9734/jocamr/2024/v25i12609

Biogenic Synthesis and Comparative Assessment of the Antimicrobial Activities of Silver and Zinc Nanoparticles of Dialium guineense Leaf Extract against Human Pathogens

Goodnews Onyedikachi Ikeh, Ugwu PE, Rita Chiamaka Okpoto, Njoku EA, Charles C. Diovu & Adonu CC · Journal of Complementary and Alternative Medical Research · 2024

Aim: The study aimed to perform a comparative evaluation of the antimicrobial activities of green synthesis of silver and zinc nanoparticles. Study Design: Experimental. Methodology: A biogenic and facile method of synthesis of silver and zinc oxide nanoparticles (DGL—SNPs and DG...

Open access Research Article 10.9734/jocamr/2024/v25i12607

Hepatoprotective Effects of Talinum Triangulare Aqueous Extract on Paracetamol-Induced Liver Damage in Wistar Rats: A Histomorphological Study

Achi Franklyn U., Chiagozie King-Bertram C., Esther I. Etu, Chinedu Maduka P., Ekoh Adaorah J. & Nyejirime, Young W. · Journal of Complementary and Alternative Medical Research · 2024

Background and Aim: Many vital bodily processes are carried out by the liver, and if it develops a disease, those processes may cease, which might seriously affect the function of the body. Talinum triangulare has been documented to possess hepato-protective, antioxidant and anti...

Open access Research Article 10.9734/jocamr/2024/v25i12608

Evaluating the Antibacterial Potential of Commercial Herbal Mixtures against Clinical Isolate of Salmonella typhi: An In-vitro Experimental Analysis

Isaac Baffour Awuah, Dennis Bardoe, Nelson Danyomah Wepia, Denis Dekugmen Yar, Daniel Hayford, Robert Bagngmen Bio, Simms Ofosu, Collins Saanle Eng, Osei-Sarfo Kantanka, George Ahiaka, Francisca Serwaa Oppong, James Azupero & Paul Acheampong · Journal of Complementary and Alternative Medical Research · 2024

Background: Typhoid fever incidence has continuously increased, particularly in developing countries. As a result, there has been an influx of preference for herbal remedies to meet the growing demand. However, the increasing demand for these herbal preparations has created room...

Open access Research Article 10.9734/jocamr/2024/v25i12605

Selected Factors that Influence Nonadherence to Antituberculosis Drug Regimen among Tuberculosis Patients at Two (2) Rural Clinics in Guyana, South America

Bhuwandai Gharbaran, Falana Daly, Viannie Ferreira, Jewel Edmondson-Carter, Cecil Boston & Andrew Hutson · Journal of Complementary and Alternative Medical Research · 2024

Objectives: This study aimed to identify and compare the factors influencing non-adherence to antituberculosis drug regimens at two rural clinics in Guyana. Methods: A quantitative, cross-sectional design was employed to examine adherence barriers among tuberculosis (TB) patients...

Open access Research Article 10.9734/jocamr/2024/v25i12606

Results of Chemical and Pharmacological Study of the Mongolian Traditional Prescription “Indra-4”

Chimedragchaa Chimedtseren, Uuganbayar Baatartsogt, Nyamdemberel Tsagaanbaatar, Dejidmaa Buyantogtokh, Myadagbadam Urtnasan & Anu Altangerel · Journal of Complementary and Alternative Medical Research · 2024

Aims: The study aims to identify the biologically active ingredients in the Indra-4 prescription and evaluate their effects on rats with acute inflammatory bowel disease (IBD) induced by lipopolysaccharide (LPS). Methodology: Thin-layer chromatography (TLC) was used to identify b...

Open access Research Article 10.9734/jocamr/2024/v25i12604

Oral Biopharmaceutics and In vitro Pharmacokinetics of Commercially Available Pharmaceutical Formulations of Paracetamol: Implications in Paediatric Medicine

Goodnews Onyedikachi Ikeh, Nwafor MN, Ndubuisi MN & Okolo KO · Journal of Complementary and Alternative Medical Research · 2024

Aim: This study aimed to compare the oral pharmacokinetics of different paediatric paracetamol dosage forms that are commercially available in Nigeria. Study Design: Experimental. Place and Duration of Study: Faculty of Pharmaceutical Sciences, Enugu State University of Science a...

Open access Research Article 10.9734/jocamr/2024/v25i12603

Exploring the Medicinal Benefits of Filfil Darāz (Piper longum L.): Insights from Unani Medicine and Modern Perspectives

Abdul Habib, Khan Sabiha Arzoo, Mohd Afsahul Kalam, Abdul Aziz, Chand Babu & Belal Ahmad · Journal of Complementary and Alternative Medical Research · 2024

Backround: Filfil Darāz (Piper longum L.) is an important medicinal plant belonging to the Piperaceae family, is therapeutically used in many traditional systems of medicine, such as Unani, Ayurveda, Siddha, etc. Purpose of Review: This review's primary goal is to investigate dat...

Open access Research Article 10.9734/jocamr/2024/v25i12602

Histomorphological Assessment of Adrenal Glands in Wistar Rats Following Myricetin Treatment Against MNU-Induced Oxidative Stress

Nsikak Michael Umoh, Paul Anyiom Odey, Williams Nnenna, Eru Eru Mba, Anani Sadeyeng, Michael Oku, Emmanuel I. Odom, Arita Okon & Francis, Christabel Ojibima · Journal of Complementary and Alternative Medical Research · 2024

Aim: This study aimed to investigate the protective effects of myricetin against oxidative stress induced by N-Methyl-N-Nitrosourea (MNU) in Wistar rats, emphasizing its impact on adrenal gland histomorphology and antioxidant enzyme activities. Study Design: The study utilized a...

Open access Research Article 10.9734/jocamr/2024/v25i12600

Andrological Potential of Aqueous Leaf Extract of Stevia rebaudiana in Male Wistar Rats

George O. Eidangbe · Journal of Complementary and Alternative Medical Research · 2024

This study aimed to investigate the effects of an aqueous leaf extract of Stevia rebaudiana (Bertoni) on male Wistar rats administered alloxan. Thirty (30) male Wistar rats, comprising six normoglycemic (NC) and twenty-four (24) alloxan-induced diabetic (D) specimens. The diabeti...

Open access Research Article 10.9734/jocamr/2024/v25i12601

A Comparative Analysis and Development of Legislative Regulatory Framework of Naturopathy and Traditional Medicines Practices in Southern Africa Region

Raphael Nyarkotey Obu · Journal of Complementary and Alternative Medical Research · 2024

Objectives: Law and policy are critical instruments for enhancing health systems. The development of modern medicine relies heavily on stringent laws and policies. Additionally, the legislative framework for naturopathy and traditional complementary alternative medicines emphasiz...

Open access Research Article 10.9734/jocamr/2024/v25i12599

Psychosocial Impacts of COVID-19 and 2014-16 Ebola Virus Disease Outbreaks on Australian - based West Africans: A Narrative Summary of Systematic Reviews

Sulaiman L Mandoh, Phillip T Bwititi & Ezekiel U Nwose · Journal of Complementary and Alternative Medical Research · 2024

Introduction: The COVID-19 pandemic resulted in widespread infection control and prevention interventions. These interventions did not only disrupt normal life activities but caused emotional and psychosocial pain, which lead to anxiety, fear of infection, stress, and distress, a...

Open access Research Article 10.9734/jocamr/2024/v25i12598