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All published articles 781

Modulatory Effects of Morphine and Xylopia aethioica Extract on Kappa Opiod Receptors (KOR), Delta Opioid Receptor (DOR), Pain Hypersensitivity and Motor Functions in Wistar Rats

B. Ukoro, S.O Ojeka, O.M Adienbo & A.N Chuemere · Journal of Complementary and Alternative Medical Research · 2024

This study investigates the modulatory effects of morphine and Xylopia aethiopica extract on kappa opioid receptors (KOR), delta opioid receptors (DOR), pain hypersensitivity, and motor functions in Wistar rats. We utilized three experimental groups: a control group receiving dis...

Open access Research Article 10.9734/jocamr/2024/v25i9567

Hippocratea africana Root Extract and Fractions Attenuated Carbon Tetrachloride-Induced Oxidative Stress and Liver Injuries in Rats

Jude E. Okokon, Martin O. Anagboso & Kufre U. Noah · Journal of Complementary and Alternative Medical Research · 2024

Hippocratea africana root is used locally in ethnomedicine to treat various diseases such as diabetes, malaria and poisoning. This work aimed to investigate the antidotal potential of the root extract and fractions against carbon tetrachloride induced liver injury to justify its...

Open access Research Article 10.9734/jocamr/2024/v25i8561

Assessing the Level of Knowledge and Health Seeking Behaviour among Diabetic Patients in the Jasikan District

Samuel Kwame Amoako Asirifi, Theodore Sutherland & Kipo Mantu Norbert · Journal of Complementary and Alternative Medical Research · 2024

Background: Diabetes is a persistent metabolic disorder characterised by high levels of blood glucose. Over time, it leads to cardiovascular, ocular, renal, and neurological damage. The most prevalent kind is type 2 diabetes, typically found in adults, which happens when the body...

Open access Research Article 10.9734/jocamr/2024/v25i8562

Factors Influencing the Healthcare-seeking Decisions of Diabetic Patients in Ghana

Samuel Kwame Amoako Asirifi, Keren-Happuch Twumasiwaa Boateng & David Zawumya Kolbilla · Journal of Complementary and Alternative Medical Research · 2024

Background: Diabetes is a persistent and progressive chronic illness that might result in permanent consequences or mortality. The significant worry in Ghana lies in the responsibility of managing the complications and mortality rates associated with diabetic patients. Timely ide...

Open access Research Article 10.9734/jocamr/2024/v25i8563

Determination of Menopausal Influence on Work Productivity among Health Workers in Public Hospitals in Kiambu County, Kenya

Warutere Peterson Njogu · Journal of Complementary and Alternative Medical Research · 2024

Aims: Menopause is a normal process in women marked by a reduction in estrogen and progesterone levels and eventual cessation of menstruation. Despite many studies on menopause, influence of menopause on work productivity and performance are poorly documented. The study sought to...

Open access Research Article 10.9734/jocamr/2024/v25i8564

Multivariate Regression Model for Stature Estimation from Arm Span, Horizontal Fingertip Reach and Foot Length of Igbo Ethnic Group of Nigeria

Loveday Ese Oghenemavwe, Peter Done Okoh, Hakeem Babatunde Fawehinmi, Lekpa Kingdom David, Faustina Chiamaka Irozulike, Michael Anozie Amadi, Chile A. Oparaocha & Celestine Ebieto Ebieto · Journal of Complementary and Alternative Medical Research · 2024

Background: Stature estimation is a major factor in biological profiling for identification of persons Aim: To formulate stature estimation models from arm Span, horizontal fingertip reach, and foot length amongst the Igbo ethnic group of Nigeria. Method:  A total of 399 subjects...

Open access Research Article 10.9734/jocamr/2024/v25i8565

Review on Pharmacological Action and Therapeutic Uses of Balchar (Nardostachys jatamansi DC): Unani Perspective

Mehwish Ayoub Khan, Mohammed Sheeraz Mushtaque Ahmed, Sumeena, Syed Farhanda Farooq & Uzma Jan · Journal of Complementary and Alternative Medical Research · 2024

Nardostachys jatamansi DC, commonly referred to as 'Balchar', is a perennial herb within the Valerianaceae family, locally known as "Jatamansi" or "Sumbul-ut-teeb". This species is indigenous to the Himalayan Mountain range, with its habitat extending across China, India, Nepal,...

Open access Research Article 10.9734/jocamr/2024/v25i8559

Machine Learning Analysis of Health and Lifestyle Factors in Understanding Diabetes

Akinkuade Oluwasina Nilei, Oke Abayomi Samuel & Ariwayo Afolabi Gabriel · Journal of Complementary and Alternative Medical Research · 2024

Diabetes poses a significant global health challenge, with approximately 537 million adults living with the condition in 2021, a number expected to rise to 783 million by 2045. To enhance predictive accuracy and gain deeper insights into the factors contributing to diabetes, this...

Open access Research Article 10.9734/jocamr/2024/v25i8560

Study of Subacute Toxicity in Wistar Rats Challenged with Phyllanthus amarus Schum and Thonn

Kpomah Enyohwo Dennis, Kpomah Bridget & Okonkwo Chisom Stanislaus · Journal of Complementary and Alternative Medical Research · 2024

Phyllanthus amarus, a widely used plant in complementary and alternative medicine practice in Southern Nigeria, is used in treating and managing numerous metabolic disorders, and neurodegenerative diseases. This study is designed to assess the subacute toxicity of P. amarus in Wi...

Open access Research Article 10.9734/jocamr/2024/v25i8558

Cadmium-induced Up-regulation of Nitric Oxide Synthase Activity in Rats' Testes: Ameliorative Effect of PurXcel

Aribo E. O., Nwangwa J. N. & Udokang N. E. · Journal of Complementary and Alternative Medical Research · 2024

Background: Cadmium is a common environmental pollutant and induces testicular dysfunction via mechanisms which include oxidative stress linked with inflammation. PurXcel is a polyherbal remedy said to be rich in antioxidants. The action of Cadmium on nitric oxide homeostasis and...

Open access Research Article 10.9734/jocamr/2024/v25i8557

Ameliorative Effect of Bambara Nut on Cognito-motor Functions of Konzo-induced Wistar Rats Model

Dimkpa V. O., David L. K. & Ajah A. A. · Journal of Complementary and Alternative Medical Research · 2024

Introduction: Konzo is a neurological disease characterized by a sudden onset of symmetrical and spastic paraparesis due to selective upper motoneuron damage. Aim: To determine the Cognito-motor modulatory functions of Bambara nut (Vigna subterranea) extract in improperly process...

Open access Research Article 10.9734/jocamr/2024/v25i8556

Sub-chronic Hepatotoxicity Assessment of Ghana Cleanser® in Exposed Wistar Rats

Uduak Peter Ise, Tayo Ibukun Famojuro, Ambi Ibrahim Maman, Ponman Nanpon Samuel, Patience Duppe & Modupe Iretiola Builders · Journal of Complementary and Alternative Medical Research · 2024

This study evaluated the toxicity of a polyherbal Formulation (Ghana Cleanser®) on liver function markers of exposed albino rats. Thirty (30) male and female rats of the Wistar strain were randomly allotted into six (6) groups with n=5. 10.0 mL/kg distilled water was given to con...

Open access Research Article 10.9734/jocamr/2024/v25i8555

Profile of Primary Headache Patients at Tanjung Priok Health Center for the Period of January – December 2023

Agus Yudawijaya, Auxilia Briliana Shirley Londo, Patria Adri Wibhawa, Ganda Pariama & Christina Roseville Lasma Aritonang · Journal of Complementary and Alternative Medical Research · 2024

Aims: To find out the profile of primary headache patients at the Tanjung Priok Community Health Center from January 2023 to December 2023. Study Design:  This research is a type of descriptive research with a cross-sectional research design. Data was obtained through secondary d...

Open access Research Article 10.9734/jocamr/2024/v25i7554

Exploring the Pharmacognostic Characteristics, Antioxidant Potential, and Anticholinesterase Activity of Piliostigma thonningii (Schum.) Milne-Redh.: Implications for Neuroprotection and Cognitive Health

Esievo, K.B., Fidelis, S.A., Gegele, I.B., Owen-Obaseki, E. & Ibrahim, J.A · Journal of Complementary and Alternative Medical Research · 2024

Aim: The aim of this research is to investigate the pharmacognostic characteristics, antioxidant potential, and anticholinesterase activity of Piliostigma thonningii (Schum.) Milne-Redh. This study seeks to evaluate its potential applications for neuroprotection and cognitive hea...

Open access Research Article 10.9734/jocamr/2024/v25i7553

Protective Effects of Terminalia superba Engl. & Diels (Combretaceae) on Aluminium Chloride-Induced Reproductive Toxicity and Oxidative Stress in Male Wistar Rats

Yannick Sani Jignoua, Sara Nathalie Edjenguèlè Béboy, Sylvain Nsangou Pechangou, Angele Nkouatchoua Tchana & Paul Fewou Moundipa · Journal of Complementary and Alternative Medical Research · 2024

Aims: Terminalia superba Engl. & Diels, also known as “Mbonga”, is a medicinal plant used by the “Baka” Pygmies of Cameroon for the management of male infertility. Many studies have demonstrated its anti-inflammatory, antiulcerative, antidiabetic and antioxidant properties. N...

Open access Research Article 10.9734/jocamr/2024/v25i7551