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All published articles 781

Evaluation of Aqueous Leaf Extract of Irvingia gabonensis on Liver Function and Antioxidant Parameters in Wistar Rats

Sylvester Agada Ogar, Ambrose Okunima, Oyinbrakemi Collins Ogu, Bright Augustine Worgu & Prohp The Prophet · Journal of Complementary and Alternative Medical Research · 2026

This study evaluated the effects of repeated oral administration of the aqueous leaf extract of Irvingia gabonensis on liver function, antioxidant parameters, and hepatic histology in healthy Wistar rats. Eighteen male Wistar rats were randomly assigned to three groups of six ani...

Open access Research Article 10.9734/jocamr/2026/v27i7765

Arsenic-induced Multi-organ Toxicity and Oxidative Stress: Protective and Pro-oxidant Effects of Corn Silk Extract in Rats

Chikodili Adolphus MBAH, Ebuka Stephen UDOM, Chukwuebuka Stanley ELEMUO, Miracle Chidinma AKOSA, Ebubechukwu Felix OFFOR, Amarachukwu Ndubuisi Ofoego, Ogochukwu Nancy ONUIGBO & Uzozie Chikere Ofoego · Journal of Complementary and Alternative Medical Research · 2026

Arsenic exposure is associated with oxidative stress and injury to metabolically active organs, including the liver, kidney and pancreas. This study evaluated the modulatory effects of ethanolic corn silk extract on arsenic-induced biochemical, oxidative and histological alterati...

Open access Research Article 10.9734/jocamr/2026/v27i7762

Sex Based Variation in Ear Morphology in a Nigerian Population: Anthropological Classification

Ugbaga Nkole Ifeanyi · Journal of Complementary and Alternative Medical Research · 2026

Aims: This study investigated the morphological characteristics of the external ear in a Nigerian population, with emphasis on sex-based variation in categorical traits and continuous anthropometric measurements, and explored their biometric and forensic implications. Study Desig...

Open access Research Article 10.9734/jocamr/2026/v27i7763

Effect of LI4 Acupressure on Pain and Distress during Intramuscular Injection in Infants: A Randomised Controlled Study

S. Shanthi & Theresa Leonilda Mendonca · Journal of Complementary and Alternative Medical Research · 2026

Introduction: Intramuscular injections are common procedures in infancy and may be associated with pain, crying, distress, and behavioral responses. Simple, safe, and feasible non-pharmacological interventions are required to support infant comfort during routine clinical procedu...

Open access Research Article 10.9734/jocamr/2026/v27i6761

Clinical and Neurobiological Effects of Aromatherapy on Depression and Sleep Disorders: A Systematic Review

Luis Cristian Guamán Sánchez, Ángel Gustavo Chacha Sinaluisa, Dennis Ricardo Pérez Gallegos & Luz Elizabeth Guamán Sánchez · Journal of Complementary and Alternative Medical Research · 2026

Aims: This systematic review evaluated the clinical efficacy of aromatherapy and the neurobiological mechanisms underlying its effects on depressive symptoms and sleep quality in adults with depression-sleep comorbidity. Study Design: A systematic review was conducted in accordan...

Open access Research Article 10.9734/jocamr/2026/v27i6760

Ameliorative Effects of Ethanol Seed Extract of Persea americana (Avocado) on Lipid Profile and Oxidative Stress Markers in Male Wistar Rats with Carrageenan-induced Inflammation

Nwankwo Emilia Chika, Meludu Samuel Chukwuemeka & Ugwu Chidiebere Emmanuel · Journal of Complementary and Alternative Medical Research · 2026

Background/Aim: Synthetic anti-inflammatory drugs, including ibuprofen, may be associated with adverse effects that affect metabolic and cardiovascular functions. This study evaluated the ameliorative effects of ethanol seed extract of Persea americana on lipid profile and oxidat...

Open access Research Article 10.9734/jocamr/2026/v27i6759

Antihypertensive and Hypolipidemic Effect of Ethyl-acetate Fraction of Adenium obesum (Forssk.) Roem. & Schult. Stem Bark Extract on L-NAME Induced Hypertension in Rats

Jwanan L. Emmanuel, Zulaihat Lawan, Oyedeji G. Oyenike, Gyenvwot P. Adamu, Dachor S. Simon & Aminu Ibrahim · Journal of Complementary and Alternative Medical Research · 2026

Introduction: Hypertension is a major health problem worldwide due to its high prevalence and its association with an increased risk of cardiovascular disease. However, the folkloric claim regarding the potential of Adenium obesum extracts and column fractions in the management o...

Open access Research Article 10.9734/jocamr/2026/v27i6758

Clinical Role of Acupressure in Preventing Postoperative Nausea and Vomiting: A Scoping Review

S. O. Oyeleke, A. A. Adebayo, D. O. Oladokun & O. Ikotun · Journal of Complementary and Alternative Medical Research · 2026

Background: Postoperative nausea and vomiting (PONV) remain one of the most distressing and prevalent complications following anaesthesia and surgery, affecting approximately 30% of unselected surgical patients and up to 80% of individuals with multiple Apfel risk factors. Despit...

Open access Research Article 10.9734/jocamr/2026/v27i6757

Inhibitory Effects of Cucurbita maxima on α-Amylase Activity and Glycemic Control in Alloxan-Induced Diabetic Rats

C. M. Okeke, C. B. Okeke, A. A. Oladejo & I. C. Anyaoku · Journal of Complementary and Alternative Medical Research · 2026

Diabetes mellitus remains a major global health challenge, necessitating the exploration of safer and more effective therapeutic agents. This study investigated the inhibitory effects of Cucurbita maxima on α-amylase activity and its impact on glycemic control in alloxan-induced...

Open access Research Article 10.9734/jocamr/2026/v27i5756

Ameliorative Effects of Ethanol Leaf Extract of Brachystegia eurycoma on Renal and Hepatic Injury in Rats with Gentamicin-Induced Acute Kidney Injury

Uyoyoghene O. Isodje, Onyekachukwu M. Adinkwu & Endurance E. Ukam · Journal of Complementary and Alternative Medical Research · 2026

Background: Kidney-liver crosstalk contributes to increased mortality from acute kidney injury. Brachystegia eurycoma leaves are used in herbal remedies to promote diuresis, treat renal stones, and address kidney issues. Aim: This study evaluated the ability of B. eurycoma to ame...

Open access Research Article 10.9734/jocamr/2026/v27i5755

Biomarkers and Personalized Medicine in Diagnosis and Treatment of Diseases: A Narrative Review

Ruchita Sharma, Nidhi Namdev & Aayushi Patud · Journal of Complementary and Alternative Medical Research · 2026

Biomarkers and personalized medicine have significantly transformed modern healthcare by enabling precise diagnosis, disease prediction, targeted therapy, and individualized patient management. Biomarkers are measurable biological indicators that reflect physiological, pathologic...

Open access Research Article 10.9734/jocamr/2026/v27i5754

Medicinal Plants Used for Female Reproductive Disorders among Indigenous Communities in Akwa Ibom State, Nigeria: A Quantitative Ethnogynaecological Study

E. N. Akpan, G. Omosun, H. I. Udo, G. G. E. Osuagwu & A. U. Ntukidem · Journal of Complementary and Alternative Medical Research · 2026

Background: Ethnogynaecological knowledge in Akwa Ibom State reflects a deeply rooted reliance on medicinal plants for women’s reproductive healthcare, yet this indigenous medical heritage remains underdocumented and increasingly vulnerable to cultural erosion. Aims: To document...

Open access Research Article 10.9734/jocamr/2026/v27i5753

Association between Conversational AI Usage and Depressive Symptoms among Young Adults in West Bengal: A Cross-sectional Study

Tanisa Ghosh, Swagata Sarkar, Ananya Ghosh, Puspen Ghosh & Avradeep Ganguly · Journal of Complementary and Alternative Medical Research · 2026

Background: Conversational artificial intelligence (AI) tools have become increasingly integrated into the daily lives of young adults for educational, emotional, and productivity-related purposes. Despite growing reliance on these technologies, their psychological impact on yout...

Open access Research Article 10.9734/jocamr/2026/v27i5752

Anti-diarrhea Effect of Loperamide Administration in Acute Castor Oil-induced Diarrhea in Pregnancy and Postnatal Outcome in Wistar Rat

Ani Celestine Okafor, Uzoefuna Casmir Chima, Chinedu Happiness Uzoagulu, Ezinwa Anthony Chijioke, Patani Oghenekparobo Patricia & Nweke Maduka Luke · Journal of Complementary and Alternative Medical Research · 2026

Background: Diarrhea during pregnancy poses significant maternal and fetal risks, particularly when associated with dehydration and electrolyte imbalance. Aim: This study investigates the effects of loperamide on castor oil-induced diarrhea in pregnant Wistar rats and evaluates i...

Open access Research Article 10.9734/jocamr/2026/v27i4751

Phytochemical and Pharmacological Potential of Black Pepper, Cinnamon, Cardamom, and Clove in Diabetes Mellitus Management: A Narrative Review

Abid Nadeem Nomani, Birjis Fatma, Jamal Akhtar & N. Zaheer Ahmed · Journal of Complementary and Alternative Medical Research · 2026

Diabetes mellitus is a major chronic metabolic disorder associated with persistent hyperglycemia and multiple long-term complications, including cardiovascular, renal, neurological, and hepatic abnormalities. Although conventional antidiabetic medications remain the primary treat...

Open access Research Article 10.9734/jocamr/2026/v27i4749