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All published articles 498

Assessment of Median Lethal Dose and Target Organ Toxicity of Oral Sub-chronic Administration of Newbouldia laevis in Mice and Rat Model of Toxicity

Ikechukwu Sonne Mbagwu, Uchechukwu Harrison Orji, Njideka Ifeoma Ani, Uchechukwu Loveth Iyanyi, Amara Anwuchaepe Ajaghaku & Daniel Lotanna Ajaghaku · Journal of Complementary and Alternative Medical Research · 2023

The acute and sub-chronic toxicities of the leaf extract of Newbouldia laevis, an ethnomedicinal herb use in the management of diabetes mellitus was investigated. For the acute toxicity study, 10 – 5000 mg/kg of the extract were administered orally to mice and obvious signs of to...

Open access Research Article 10.9734/jocamr/2023/v21i4443

Effects of Aloe barbadensis and Cymbopogon citratus on Blood Glucose Levels of Alloxan–Induced Diabetic Albino Rats

V. O. Offor, A. N. Ufele, B. U. Ononye, U. C. Aghalu, P. I. Afoemezie, E. I. Azaka & C. F. Chude · Journal of Complementary and Alternative Medical Research · 2023

Diabetes is a heterogeneous complex metabolic disorder characterized by elevated blood glucose concentration, and glycosuria resulting from insulin deficiency. This project was embarked upon to investigate the effects of Aloe barbadensis and Cymbopogon citratus on blood glucose l...

Open access Research Article 10.9734/jocamr/2023/v21i3441

Emotional Intelligence among Employees at PTITP

Yunita R. M. B. Sitompul, Putu Deba Ratma Asthiti & Luana N. Achmad · Journal of Complementary and Alternative Medical Research · 2023

Work stress is an inability to keep up with work pressure because of the high demands that are not balanced by the employee's competence. Work stress can be influenced by many things, including Emotional Intelligence (EI). Employees who have high EI can manage their work stress....

Open access Research Article 10.9734/jocamr/2023/v21i4442

Evaluating the Protective and Ameliorative Effects of Kolaviron on Lead-induced Adrenal Gland Toxicity in Adult Wistar Rats

Christian Chiemeka Ozor, Godslove Ugochukwu Egbuta & Chiadikobi Lawrence Ozoemena · Journal of Complementary and Alternative Medical Research · 2023

Lead (Pb) toxicity is possibly the most common form of heavy metal poisoning in the human body due to the abundant global distribution and utilization of Pb. Pb has no functional role in the body. Its only effect on human organs is regarded as harmful. The adrenal gland, one of t...

Open access Research Article 10.9734/jocamr/2023/v21i3439

Preclinical In vivo Acute Toxicity Testing of Hyrdoethanolic Extracts of Ficus thonningii Blume (Moraceae) on Wistar Rat Models

Estella Tembe Fokunang, Ngo Biyiha Marilyn Orlane Ara, Ambassa Pantaleon, Njinkio Nono Borgia Legrand, Ngameni Bathelemy & Fokunang Charles · Journal of Complementary and Alternative Medical Research · 2023

Ficus thonningii (Blume) is a medicinal plant whose biological activity has been demonstrated in the management of peptic ulcers. Unfortunately, little scientific data exists on its toxicity. This is why we studied the acute and subacute oral toxicity profile of the hydro-ethanol...

Open access Research Article 10.9734/jocamr/2023/v21i3438

Phytochemical Screening and Evaluation of the Anti-Salmonella Activity of Leaf Extracts of Telfairia occidentalis Hook. F. (Cucurbitaceae) on Salmonella typhii Cell Culture

VL Tamanji, EAF Tembe, GA Mbong, H Bayaga, BN Njinkio, DJ Fonmboh, MV Tchadji, JO Moody, HK Gonsu & CN Fokunang · Journal of Complementary and Alternative Medical Research · 2023

Typhoid fever, a bacterial infection caused by Salmonella typhi whose treatment is by use of antibiotics. And the use of these antibiotics associated with drug resistance, high cost of medication and less accessibility to rural populations remains an issue of concern. The aim of...

Open access Research Article 10.9734/jocamr/2023/v21i3437

Relationship of Adrenaline Administration to Increased Blood Sugar Levels in Male Rattus norvegicus Rats

Achnes Pangaribuan & Frisca Ronauli Batubara · Journal of Complementary and Alternative Medical Research · 2023

Stress is a condition that causes a steady state in the body to be disrupted. When a stressor hits the body, the hypothalamus will send a signal to the adrenal gland to produce catecholamine. One of the catecholamines is adrenaline. Adrenaline will increase heart muscle contracti...

Open access Research Article 10.9734/jocamr/2023/v21i3436

Relationship between Degrees of Nasal Obstruction and Obstructive Sleep Apnea

Lina Marlina, Wendy Hendrika & Marsya Adinda · Journal of Complementary and Alternative Medical Research · 2023

Obstructive sleep apnea (OSA) is a sleep-related breathing disorder caused by repeated upper airway obstruction. In OSA patients, 46.5%-58% reported having symptoms of hypersomnolence or excessive daytime sleepiness, and it was the most common symptom. Nasal obstruction is consid...

Open access Research Article 10.9734/jocamr/2023/v21i2435

Hematological and Hypoglycemic Effects of Ethanolic Extract of Annona muricata Ripe Fruits Pulp on Streptozotocin-induced Diabetes in Rats: In vivo and In silico Studies

O. S. Akinlolu, T. H. Fatoki & D. U. Momodu · Journal of Complementary and Alternative Medical Research · 2023

Diabetes mellitus has been a metabolic disorder characterized by interferences in the breakdown of carbohydrate, lipid, and protein as a result of insulin deficiency. Great efforts are ongoing in understanding and management of diabetes, and disease related complication. In this...

Open access Research Article 10.9734/jocamr/2023/v21i2434

Phytochemical, Antioxidant, Cytotoxicity and Antimicrobial Investigations of Tephrosia platycarpa GUILL. & PERR.

Sunday Kunle Ogundairo, Olaoluwa O. Olaoluwa & Olapeju O. Aiyelaagbe · Journal of Complementary and Alternative Medical Research · 2023

Tephrosia genus belongs to the family Fabaceae and plants in this genus have been reported to possess antimicrobial, anti-inflammatory and pesticidal properties, however; there is paucity of information on the chemical and biological activities of Tephrosia platycarpa. Thus, this...

Open access Research Article 10.9734/jocamr/2023/v21i2432

Neuroprotective Effect of Stachytarpheta angustifolia Methanol Extract Against Aluminium Chloride (AlCl3) Induced Alzheimer’s Disease in Albino Rats

Benedict A. Ashikaa, Moses Z. Zaruwa, Bawa Y. Muhammad, Titilayo O. Bamidele & Moses A. Daikwo · Journal of Complementary and Alternative Medical Research · 2023

Aim: This study was aim to evaluate the neuroprotective effect of Stachytarpheta angustifolia methanol extract on aluminium chloride induced Alzheimer’s disease in Albino rats. Study Design: This is an experimental study. Location and Duration of the Study: The research was condu...

Open access Research Article 10.9734/jocamr/2023/v21i2433

Utility of Repertory of the Homoeopathic Materia Medica by J. T. Kent (Kent’s Repertory) in the treatment of Chronic Suppurative Otitis Media: A Prospective Observational Study

Sapna Salodiya, B. P. Srivastava & Ayesha Naaz · Journal of Complementary and Alternative Medical Research · 2023

Background: Chronic Suppurative Otitis Media is a long standing infection of middle ear with intermittent or persistent otorrhoea through perforated tympanic membrane for more than 6 weeks duration. It is more prevalent in developing nation than developed countries. In India the...

Open access Research Article 10.9734/jocamr/2023/v21i2431

Determination of Antibiotic Prescription Pattern in Private Healthcare Facilities in Port Harcourt Metropolis, Rivers State, Nigeria

A. T. O. Awopeju & I. Chijioke-Nwauche · Journal of Complementary and Alternative Medical Research · 2023

Background: The consequences of antimicrobial resistance are severe, as mortality and morbidity rates continue to increase. The extensive use of antibiotics contributes significantly to the development and spread of antimicrobial resistance. It is crucial to have knowledge suppor...

Open access Research Article 10.9734/jocamr/2023/v21i3440

Modulatory Activity of Aju Mbaise Polyherbal Formulation on Serum Proinflammatory Cytokines and Prostaglandin Levels in Nulliparous and Parturient Female Albino Rats

Vincent Kalu Agu, Uwadiegwu Achukwu, Solomon Nnah Ijioma & Bernard Nonyerem Kafor · Journal of Complementary and Alternative Medical Research · 2023

Aju Mbaise (Ajumbise), which traces its origin to the people of Mbaise in the Owerri Senatorial District of Imo State in Nigeria, is a composite mixture of approximately eight herbal plants in the forms of herbs, barks, and roots, used for the management of delivery pains, postpa...

Open access Research Article 10.9734/jocamr/2023/v21i1430

Does Oral Administration of Fresh and Dry Ginger (Zingiber officinale) Juice have Effect on the Lipid Profile of Albino Rats

Helen Anthony Waribo, Emmanuel Chukwu Ani & Atoukaritou Omodi Osuosa · Journal of Complementary and Alternative Medical Research · 2023

Aim: This study compares the effect of fresh and dry ginger juice on the lipid profile of albino rats. Methodology: Fifteen(15) albino rats with average weight of 150g divided into three groups of five (5) rats each were used for the study.5ml of the ginger juice was administered...

Open access Research Article 10.9734/jocamr/2023/v21i1428