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All published articles 781

Sub-Chronic Effects of Pausinystalia yohimbe Methanol Extract on Cardiac and Inflammatory Biomarkers in Male Wistar Rats

Imafidon Joseph Omogiade, Aghatise Kevin Erhamwonyi, Omogiade Christabe C.A., Ekoyata Charles & Samuel Obuele Idibagen · Journal of Complementary and Alternative Medical Research · 2025

Introduction: In sub-Saharan Africa, herbal aphrodisiacs are frequently used to improve sexual performance. Because of its bioactive alkaloid yohimbine, an α-adrenergic receptor antagonist that is known to alter sympathetic activity and vascular tone, Pausinystalia yohimbe (Buran...

Open access Research Article 10.9734/jocamr/2025/v26i10719

Hydrotherapy as a Complementary Approach in Hypertension Management: A Narrative Review

Naveen Kumar D, Geetha B. Shetty, Sujatha K J & Prashanth Shetty · Journal of Complementary and Alternative Medical Research · 2025

Background: Hypertension remains a leading global risk factor for cardiovascular disease. Complementary non-pharmacological therapies that reduce blood pressure (BP) and improve vascular function are of growing interest. Hydrotherapy including warm or hot-water immersion, aquatic...

Open access Research Article 10.9734/jocamr/2025/v26i10718

Precision Nanomedicine Converging AI and Multi-Omics: A Comprehensive Review of Cross-disease Applications in Cancer, Diabetes, and Cardiovascular Therapies

Samad Ali, Saklain Mostak Siam, K.M. Navid-Al-Islam, Md. Asadul Haque & Abdus Sobhan · Journal of Complementary and Alternative Medical Research · 2025

Aims: Targeting non-specific action, low bioavailability, and systemic toxicity have always been some of the major limitations of medicinal therapies for cancer, diabetes, and CVDs. Here, we provide an overview of a precision nanomaterial integrating AI, multi-omic data, and stim...

Open access Research Article 10.9734/jocamr/2025/v26i10717

The Effect of Cannabis and Methamphetamine on Liver and Kidney Function in Adult Male Wistar Rats: A Comparative Study

Ezeokafor Nonso Emmanuel, Malachy Nancy Chisom, Mmaju Chidinma Ifeyinwa, Nwaefulu Kester Eluemunor, Sobanke Ayobami Omolara, Chukwumbah Emmanuel Chukwuemeka, Egbunike Chijioke Geoffery, Okeke Blessing Chidinma & Ezeadum Kosisochukwu · Journal of Complementary and Alternative Medical Research · 2025

Cannabis and methamphetamine are widely abused substances with potential harmful effects on various organs, including the liver and kidneys. An initial step in detecting liver or kidney damage is to carry out a blood test to determine the level of certain liver enzymes or the lev...

Open access Research Article 10.9734/jocamr/2025/v26i9716

Effects of Helicobacter Pylori on Gastric Cancer in the Adult Population: A Systematic Review

Aayam Sapkota, Gichin Changaramkumarath, Jane M. Abucha, Mekdes M. Wollel, Nethra Somannagari, Alousious Kasagga & Ann Kashmer Yu · Journal of Complementary and Alternative Medical Research · 2025

Gastric cancer is a cancer that leads to high mortality worldwide. Helicobacter pylori (H. pylori) infection is a major risk factor for gastric cancer. This review covers non-cardia and cardia gastric adenocarcinomas (both clinically and histopathologically confirmed) according t...

Open access Research Article 10.9734/jocamr/2025/v26i9715

Occupational Prevalence of Carpal Tunnel Syndrome in Textile Industry Workers

Ansuman Singh, Tanzila Mulla, Ashutosh Sharma & Atul Kumar Singh · Journal of Complementary and Alternative Medical Research · 2025

Background:  Carpal Tunnel Syndrome (CTS) is a common neuropathy caused by median nerve compression in the wrist, often linked to repetitive hand and wrist movements. Textile workers are especially at risk due to prolonged manual tasks and faulty postures. CTS can cause pain, num...

Open access Research Article 10.9734/jocamr/2025/v26i9714

Safe and Effective Use of Herbal Medicinal Products: A Model of Interdependent Militating Factors

Adepoju Tunde Joseph OGUNKUNLE · Journal of Complementary and Alternative Medical Research · 2025

Background: The growing reliance on herbal medicine carries inherent risks, as concerns over the safety and efficacy of these products persist. Therefore, the objectives of this study were to identify the factors that compromise the safe and effective use of herbal medicinal prod...

Open access Research Article 10.9734/jocamr/2025/v26i9713

Effects of Tetrapleura tetraptera (Aidan Fruit) on Uterine Weight and Reproductive Hormones in Postpartum Wistar Rats

Godson K.P & ThankGod C. Omuruka · Journal of Complementary and Alternative Medical Research · 2025

Tetrapleura Tetraptera (TTE), commonly known as Aidan is a medicinal and nutritional plant distributed in the lowland forests of tropical. Despite its traditional usage to enhance breast milk production and support uterine recovery after delivery, its effect on a postpartum uteru...

Open access Research Article 10.9734/jocamr/2025/v26i9712

Chemical Composition and In vitro Antioxidant Studies on Annona Muricata Fruit

Mosimabale M. M, Akinola O. O, Orji I. G, E.D. Manuel-Mosi, Olatunji I. I, Ayodeji Famuti & Olusola Ladokun · Journal of Complementary and Alternative Medical Research · 2025

The objective of this study was to examine the nutritional composition, conduct a proximate analysis, identify phytochemical constituents, and assess the in vitro antioxidant activities of Annona muricata flesh, seed, and bark, with the intention of highlighting their potential a...

Open access Research Article 10.9734/jocamr/2025/v26i9710

Neuroprotective Effects of Piper methysticum against Phenytoin-Induced Cognitive Impairment in Mice

Olayemi K. Wakeel, Olaniyi Samson & Mathew K. Bello · Journal of Complementary and Alternative Medical Research · 2025

Cognitive impairments are a common comorbidity in epileptic patients, resulting from both the underlying neurological disorder and antiepileptic medication. Phenytoin, a widely prescribed anticonvulsant, has been shown to negatively impact cognitive function. This investigation a...

Open access Research Article 10.9734/jocamr/2025/v26i9711

Leveraging AI-Driven Simulation Training to Mitigate Defensive Medicine in Clinical Practice

Kimberly Morton Cuthrell · Journal of Complementary and Alternative Medical Research · 2025

Defensive medicine remains widespread and expensive across global healthcare systems. The evolving healthcare landscape and defensive medicine practices are undergoing significant transformations with groundbreaking implementations of artificial intelligence (AI). Defensive medic...

Open access Research Article 10.9734/jocamr/2025/v26i9709

Role of Ahara (Scheduled Diet) and Udvarthana with Shaileyadi Churna in Sthoulya: A Case Study

Harish Deshpande · Journal of Complementary and Alternative Medical Research · 2025

Sthoulya is considered among Ashtaninditya Purusha where a person body weight is increased rapidly within short duration. In Ayurveda, the global problem of obesity has been mentioned to as Sthoulya or Medhoroga in classical texts by the majority of Acharyas under the moniker of...

Open access Research Article 10.9734/jocamr/2025/v26i9707

Traditional Cosmeceutical and Therapeutic Uses of Shea Butter (Vitellaria paradoxa) in the Maritime Region of Togo

Mlatovi DEGBE, Fidèle Sefakor Nana NYAYEE, Akouvi Wotsa Mawuli AKAKPO, Boé Berthine Toubaté & Amivi TETEBENISSAN · Journal of Complementary and Alternative Medical Research · 2025

Introduction: Shea butter (Vitellaria paradoxa), revered as "women's gold," is a vital socio-economic and cultural resource in Togo. However, the associated traditional knowledge, transmitted orally, is poorly documented and threatened by urbanization and ecological pressures. Th...

Open access Research Article 10.9734/jocamr/2025/v26i9708

Antidiabetic Potential of GlucoGuard, a Polyherbal Formulation in Type 2 Diabetes Management

Enema Onojah John, Imoh Imeh Johnny & Ogechi Innocentia Obasi · Journal of Complementary and Alternative Medical Research · 2025

Type 2 diabetes mellitus (T2DM) affects over 500 million adults worldwide, yet current pharmacotherapies often provide only partial glycemic control and may cause adverse effects. Polyherbal formulations can offer complementary benefits through synergistic mechanisms and reduced...

Open access Research Article 10.9734/jocamr/2025/v26i9706

Analyzing Heavy Metals and Minerals in Methanolic Leaves, Stem, and Root Extracts of Bryophyllum pinnatum, Cochlospermum tintorium, and Erythrina senegalensis: Exploring the Public Health Implications

TijwunTweinpu Luka, Peter Anjili Mshelia, Luka Waira Tijwun, Atiben Atisakunten, Abdulrasheed Abubakar, Shaibu Rahab, Gidado Joshua Danladi & Sanda kyari Abba · Journal of Complementary and Alternative Medical Research · 2025

This study investigated the distribution of heavy metals and mineral elements in the methanolic extracts of leaves, roots, and stems of Bryophyllum pinnatum, Cochlospermum tintorium, and Erythrina senegalensis in Takum, Taraba State. The concentrations of these elements were anal...

Open access Research Article 10.9734/jocamr/2025/v26i9704