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Lifestyle and Psychosocial Determinants of Hyperprolactinemia among Reproductive-age Women in Enugu and their Implications on Infertility: A Cross-Sectional Study

Hector Okechukwu Obianyido, Ozioma Ebere Obianyido & Chiemelie Onwasoigwe · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Background: Hyperprolactinemia is a significant endocrine disorder among women of reproductive age and is strongly associated with menstrual disturbances, anovulation, and infertility. Psychosocial and lifestyle factors have been suggested as potential contributors, yet evidence...

Open access Research Article 10.9734/ajbgmb/2025/v17i12512

Retrogradation of Sorghum Starch: An Investigation into the Effects of Alcohol and Water

Ojima, S., Denis, J., Hassan, I. S., Maishanu, S. A. & Emmanuel, O. · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

This study investigated the retrogradation behavior of sorghum starch (Sorghum bicolor) under the influence of alcohol and water, with emphasis on changes in physicochemical properties relevant to food, pharmaceutical, and industrial applications. Sorghum starch was extracted usi...

Open access Research Article 10.9734/ajbgmb/2025/v17i12509

CpG Methylation in the 1F Promoter of the NR3C1 Gene and its Biomarker Potential in Post-Traumatic Stress Disorder

Banu Rustamli · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

PTSD is a disorder that is described to cause by disruption of psychoneurological and biological processes in military personnel due to war-related trauma, excessive stress and exposure to extreme environments. Specifically, stability of the means of stress response is also influ...

Open access Research Article 10.9734/ajbgmb/2025/v17i12507

Crossbreeding German Brown x N’dama Cattle at Ibadan, Nigeria: Heterosis for Reproductive and Productive Traits in the Crossbreds

I. C. Nwosu · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

The aim of this study was to investigate the effects of animal trait and level of local cattle gene inheritance on the expressed levels of heterosis in crossbreeding of exotic German brown and local N’dama. Records from 199 pure bred German brown and N’dama and 308 crossbred calv...

Open access Research Article 10.9734/ajbgmb/2025/v17i12508

Presence and Abundance of Microplastics in Benthic Organisms from Some Niger Delta, Nigeria Coastal Rivers

KPAKOL, N. N., BELONWU, D. C & OMEODU, S. I. · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Presence and abundance of microplastics in benthic organisms from some Niger Delta, Nigeria Coastal Rivers were investigated. This study was carried out using 120 samples each of Crabs, Periwingles, Oysters, Sea Stars, Shrimps, Lobsters, Crayfish Samples, all from Bonny, Qua Iboe...

Open access Research Article 10.9734/ajbgmb/2025/v17i12506

Expression and Characterization of Recombinant PETase in E. coli BL21(DE3) for PET Plastic Degradation

Vundeti Sanjana Priya · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Aim: Plastic pollution caused by the persistence of polyethylene terephthalate (PET) has become a major environmental challenge due to its resistance to natural degradation. Biocatalytic degradation using PETase provides an eco-friendly and sustainable solution for PET recycling....

Open access Research Article 10.9734/ajbgmb/2025/v17i11505

Preliminary Study on Polyherbal Formulation as a Postpartum Health Intervention: Insights into Wound Healing, Inflammation Modulation, and Lactation Support

Madhumitha G, Nikkath Sulthana M H, Gayathri V & Pujaa B · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

The time after conceptus birth when the mother's physiological and anatomical alterations revert to their pre-pregnancy state, is known as the postpartum period. Topical medications and antimicrobials can reduce the risk of infection during the healing process. Antibiotics have b...

Open access Research Article 10.9734/ajbgmb/2025/v17i11504

Nutritional Efficiency of Corn and African Pear Consumed as Complementary Snacks

Ezennaya, C. F, Nwobodo, A. M, Ezeigwe O.C, Ogunwa, S.C, Okoro, C.O, David, E. E & Igwenyi, I. O · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Aim: This study aimed to analyze the nutritional content of boiled Zea mays and Dacryodes edulis. This study evaluated the proximate, phytochemical, vitamin, and mineral composition of boiled Zea mays (maize) and Dacryodes edulis (African pear).  Methods: Standard biochemical met...

Open access Research Article 10.9734/ajbgmb/2025/v17i11503

Cardiotoxicity Screening of Commelina diffusa (Dayflower) Aqueous Extract in Female Wistar Rats: Acute, Sub-Acute, and Chronic Effects Following OECD 425 Guidelines

Wellington, E. O, ThankGod, I.E. & Yerinbide, O · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

This study investigated the potential cardiotoxic effects of Commelina diffusa aqueous extract in female Wistar rats, following the guidelines set by the OECD Test No. 425 for acute oral toxicity. Commelina diffusa is a medicinal plant traditionally used for therapeutic purposes;...

Open access Research Article 10.9734/ajbgmb/2025/v17i11502

A Retrospective Study on Sexually Transmitted Infections among Patients in General Hospital, Okigwe, Imo State, Nigeria

Uka-Kalu, Ezinne Chioma, Elekeh, Rosemary Ichita & EZE, PECULIAR ADAOBI · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Sexually transmitted infections (STIs) remain a global public health challenge due to their high prevalence, asymptomatic presentation, and severe complications, particularly their association with HIV/AIDS. Given the scarcity of research in Nigeria, particularly at the Universit...

Open access Research Article 10.9734/ajbgmb/2025/v17i11500

Amylase from Aspergillus niger: Its Production, Partial Purification and Biochemical Characterization for Industrial Application as Eco-Friendly Detergent Additive

Catherine Joke Adeseko & Deborah Kehinde Odewale · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Amylase, a crucial enzyme within biological systems, reveals its catalytic effectiveness in facilitating the breakdown of complex carbohydrates through hydrolysis. This study sought to isolate, partially purify, and investigate the inherent physicochemical properties of amylase d...

Open access Research Article 10.9734/ajbgmb/2025/v17i11501

Host-specific Gut Microbiomes in Three Estuarine Crabs

Hiya Master, Ira Kode, Siddhant Pandita, Eniya Tapo, Supriya Mukherjee & Vikas Jha · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Crab-associated microbiomes play critical roles in host nutrition, immunity, and ecological adaptation, yet remain poorly characterized for many ecologically and economically important species. Here, we present the first high-throughput 16S rRNA gene sequencing analysis of gut mi...

Open access Research Article 10.9734/ajbgmb/2025/v17i10499

Harnessing the Human Microbiome for Next-Generation Drug Discovery

Raimot Efunyinka Junaid-Eko, Ugochi Beauty Okoro, Yetunde Grace Orogun, Timothy Umoru Edibo, Victor Damilare Oladele, Damian Ndubuisi NWAJEI & Adibia Umoroye Nathan · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

The human microbiome, a complex ecosystem of trillions of microorganisms, is now recognized as a virtual endocrine organ that profoundly influences host physiology. Beyond its role in metabolism and immunity, the microbiome produces a vast repertoire of small molecules that can m...

Open access Research Article 10.9734/ajbgmb/2025/v17i10498

In Silico Design and Computational Characterization of a Multi-Epitope Immunotherapeutic Candidate Targeting MYC and CTNNB1 for Hepatocellular Carcinoma

Kushal Wangdale & Nannaparaju Vaishnavi · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Aims: To design, validate, and partially express a novel large molecule immunotherapeutic candidate targeting MYC and CTNNB1, key oncogenes implicated in hepatocellular carcinoma (HCC), using in silico computational approaches. Study Design: In Silico Studies using Computational...

Open access Research Article 10.9734/ajbgmb/2025/v17i10497

Evaluation of the Antidiabetic Effects of Cashew Plant (Anacardium occidentale) on Alloxan-Induced Wistar Albino Diabetic Rats

M. K. Jiyil, K.G Wilson, C. E. Mafuyai, C.P Japhet, M.I. Shago & C. D. Luka · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

According to the World Health Organisation, over 537 million adults currently live with diabetes. Despite the availability of pharmacological treatments such as insulin and oral hypoglycemic agents, these options often come with significant drawbacks. As a result, there is increa...

Open access Research Article 10.9734/ajbgmb/2025/v17i10496