Aims:.Cervical cancer is predominantly associated with persistent infection from high-risk human papillomavirus (HPV) strains, especially HPV16.This study focuses on the in silico design of a multiepitope- based recombinant vaccine targeting the E6 and E7 oncoproteins of HPV16. T...
Open access
Research Article10.9734/ajbgmb/2025/v17i10495
There are many persistent heavy metals released into our environment, among which are heavy metals. This study was conducted to determine the concentrations of selected heavy metals—cobalt (Co), manganese (Mn), iron (Fe), and silver (Ag)—in fish, water, and sediment samples colle...
Open access
Research Article10.9734/ajbgmb/2025/v17i10494
Aim: To correlate the biological effect of sialic acid on the expression of high mobility genes in the human astrocytoma cell line with regard to its therapeutic potential. Methodology: After the treatment of 1321N1 cells (human astrocytoma cells) with Sialic acid in different do...
Open access
Research Article10.9734/ajbgmb/2025/v17i9493
Introduction: Hypovitaminosis D is a real public health problem. Populations in sub-Saharan Africa, despite favorable sun exposure, are not immune to this scourge. Among the reasons mentioned are the inhibitory action of melanin on the cutaneous synthesis of vitamin D but also th...
Open access
Research Article10.9734/ajbgmb/2025/v17i9492
In Nigeria, shrimps, commonly referred to as crayfish, represent a highly nutritious food source offering substantial amounts of protein, essential fatty acids, vitamins, and minerals, thus contributing significantly to dietary needs. Shrimps and other marine species are crucial...
Open access
Research Article10.9734/ajbgmb/2025/v17i9491
Background: Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by persistent inflammation and oxidative stress, with reactive oxygen species (ROS) playing a key role in its pathogenesis. Silver nanoparticles (AgNPs) possess redox-modulating and immunomodulat...
Open access
Research Article10.9734/ajbgmb/2025/v17i9490
Almost half of cases of infertility, which is defined as the inability to conceive after a year of unprotected sexual activity, are caused by male factors. Infertility is still a global health concern. The mitochondria are one of the main biological contributors to energy metabol...
Open access
Research Article10.9734/ajbgmb/2025/v17i9489
Background: Self-monitoring of blood glucose is essential for effective diabetes management, necessitating the use of glucometers that maintain precision and accuracy. Environmental factors and prolonged usage may impact their performance. However, there is limited knowledge rega...
Open access
Research Article10.9734/ajbgmb/2025/v17i9487
Pathogenic microorganisms are constantly developing resistance, hence the need for medicinal plant remedies; Allium cepa (Onion),Allium sativum (Garlic) and Zingiber officinale (Ginger) have been playing a vital role on the health and healing of man since human civilization. The...
Open access
Research Article10.9734/ajbgmb/2025/v17i9486
The present study investigated the comparative effects of varying intensities of alternating magnetic field and Tithionia diversifolia crude extract on hematological parameters of mice infected with Plasmodium berghei. Experimental solenoids were designed to generate the magnetic...
Open access
Research Article10.9734/ajbgmb/2025/v17i8485
As the population of the earth is increasing, the rate of waste release into the environment increases. This study investigates the microbial composition of wastewater samples collected from the Wupa Wastewater Treatment Plant in Abuja, focusing on bacterial and fungal diversity....
Open access
Research Article10.9734/ajbgmb/2025/v17i8484
Ugochukwu M. Okezie, Kamsiyochukwu. P. Ezeh, Emmanuel O. Enyi, Chigozie C. Ezeagha, Chigozie U Awegbe, Chinua W. Onyebuchi, Uzochukwu C. Ibe, Pass C. Chijindu & Edegbe Felix Osogu·Asian Journal of Biochemistry, Genetics and Molecular Biology·2025
Aims: Endophytic fungi are producers of important bioactive compounds with several biological activities. Endophytic fungi are known to reside within the internal tissues of plants. Hyptis suaveolens is a medicinal plant cultivated in Nigeria for its therapeutic potential. Study...
Open access
Research Article10.9734/ajbgmb/2025/v17i8483
Background: Malaria is responsible for significant morbidity and mortality, especially in sub-Saharan Africa. Malaria can lead to complications involving vital organs such as the liver and spleen, intensifying the need for new therapeutic strategies. Historically, medicinal plant...
Open access
Research Article10.9734/ajbgmb/2025/v17i8482
Aim: To identify some acyclic phosphate resistant genes in hepatitis B positive subjects attending Rivers State University Teaching Hospital Study Design: Analytical Cross-sectional study. Place and Duration of Study: Rivers State University Teaching Hospital, between February an...
Open access
Research Article10.9734/ajbgmb/2025/v17i8480
Obiajulu Christian Ezeigwe, Ebele Lauretta Iloanya, Chiamaka Vivian Okochi, Ngozichukwu Immaculata Achara, Benneth Nnanyelugo Enemchukwu, Chidinma Felicia Ezennaya & Shedrack Chinedu Ogunwa·Asian Journal of Biochemistry, Genetics and Molecular Biology·2025
Diarrhea is a common gastrointestinal disorder that is one of the causes of morbidity and mortality in both children and adults. Ocimum gratissimum has been used in traditional medicine as a household remedy for various diseases, including diabetes, biliary diseases, cough, wound...
Open access
Research Article10.9734/ajbgmb/2025/v17i8481