Background: The aim of this study was to identification of polymorphisms of FOLH1 and DISC1 genes in Iranian patients with schizophrenia. Materials and Methods: In this case-control study, 50 patients with schizophrenia and 50 healthy controls were evaluated. PCR-RFLP and Tetra-A...
Open access
Research Article10.9734/ajbgmb/2019/v2i230056
Background: PD-L1 is the main ligand is expressed on many tumors including lung cancer and is expressed in hematopoietic cells and various leukemia. The aim of this study was to evaluate the expression of PD-1 gene and the evaluation of cancerous grades of NSCLC and its subclasse...
Open access
Research Article10.9734/ajbgmb/2019/v2i230055
Aim: This study is aimed at investigating the ameliorative efficacy of methanolic extract of Corchorus olitorius leaves against acute ethanol-induced oxidative stress in Wistar rats. Methods: Fresh plants of C. olitorius were harvested from the Institute of Agricultural Research...
Open access
Research Article10.9734/ajbgmb/2019/v2i230054
Entandrophragma angolense is a plant of the family Meliaceae of African pharmacopoeia. It is used in traditional medicine as an analgesic and anti-inflammatory in cases of abdominal or hips pain. The aim of this study is to compare the effect of oral administration of aqueous ext...
Open access
Research Article10.9734/ajbgmb/2019/v2i130053
Background: Coumarins (2H-1-benzopyran-2-one), an important class of heterocyclic compounds, and its derivatives can be found in many natural or synthetic drug molecules and possess versatile bioactivities making them important molecules for medical practitioners and medicinal ch...
Open access
Research Article10.9734/ajbgmb/2019/v2i130052
Aim: To investigate the effect of Carica papaya seed extract on KBrO3 - induced nephrotoxicity in rats. Renal toxicity was induced by a single oral dose of 100 mg/kg body weight of KBrO3. Study Design: Thirty (30) male albino rats were divided into six groups, five rats per group...
Open access
Research Article10.9734/ajbgmb/2019/v2i130051
Background: Polycystic ovarian syndrome (PCOS) a common endocrinological disorder among women in the reproductive age group, is associated with hyperinsulinemia/Insulin resistance, obesity, menstrual irregularities and anovulation. Aim and Objectives: The present study was conduc...
Open access
Research Article10.9734/ajbgmb/2019/v2i130050
The influence of age and sex on the levels of glycosylated haemoglobin among non-diabetic Nigerian population were investigated in this study. Seventy-nine non-diabetic individuals volunteered for the study and were grouped into male and female and then into four groups according...
Open access
Research Article10.9734/ajbgmb/2019/v2i130049
The aims of the present study were to evaluate the antioxidant activity and DNA Protective effect of Helleborus orientalis (HO) leaf extract against oxidative damage, and to determine the total phenolic and flavonoid contents of the plant species studied. Methods: The total pheno...
Open access
Research Article10.9734/ajbgmb/2018/v1i430047
Objective: This study was carried out with an objective to investigate the impact of biochar on phytochemical composition in plant especially Etlingera elatior cultivated on different dosage of biochar. Methods: Etlingera elatior was cultivated on the pot with 20 cm diameter and...
Open access
Research Article10.9734/ajbgmb/2018/v1i430048
The study examined the cardioprotective potential of the ethanolic extract of Citrullus lanatus in streptozotocin induced diabetic albino rats. A total of sixty albino rats weighing approximately ± 200 g were used. The induction of diabetes in the rats was done using 50 mg/kg bod...
Open access
Research Article10.9734/ajbgmb/2018/v1i430046
Aims: To improve a multiple-locus variable-number tandem-repeat (VNTR) analysis (MLVA) assay for Helicobacter pylori typing. Materials and Methods: Polymorphic VNTRs were searched by Gene Expert. The distribution and polymorphism of each VNTR locus were analyzed in 18 H. pylori g...
Open access
Research Article10.9734/ajbgmb/2018/v1i430045
The genotoxic potentials of two water-based oilfield chemicals on edible aroids were investigated. Five accessions of Colocasia eculenta and three accessions of Xanthosoma maffafa were exposed to graded concentrations of sodium azide and potassium chromate; while the accessions w...
Open access
Research Article10.9734/ajbgmb/2018/v1i429646
Background: Chromosome staining using G banding is a commonly used technique during karyotyping, however, a limited number of laboratories carries out the test. Blood samples must be sent to the laboratory on the same day of sample collection. Aim: To assess the effect of time pa...
Open access
Research Article10.9734/ajbgmb/2018/v1i329640
Introduction: Leukemia is the commonest malignancy of childhood and is the causative of a third of childhood cancer deaths. Lipid abnormalities have been recognized in children with acute lymphoblastic leukemia (All). Kidney involvement in leukemia can be quite immense. Aim: This...
Open access
Research Article10.9734/ajbgmb/2018/v1i329639