The emergence of fungal resistance to antifungal agents is a significant concern, it leads to treatment failure and poor clinical outcomes. Fungal infections pose significant concern to human health, agriculture and the environment. Hence the need for alternative antifungal agent...
Open access
Research Article10.9734/ajbgmb/2025/v17i5464
This study aimed to investigate the role of oxidative stress in the toxicity induced by smoked fish extract in albino rats, with a particular focus on the biochemical markers of oxidative damage. A total of 20 male albino rats, weighing 180–220 g, were divided into four groups: a...
Open access
Research Article10.9734/ajbgmb/2025/v17i5463
This study aimed to evaluate the histopathological effects of smoked fish extract on liver and kidney tissues in albino rats, focusing on the structural damage induced by prolonged exposure to smoked fish contaminants. A total of 20 male albino rats (mean weight: 200 ± 12.5 g) we...
Open access
Research Article10.9734/ajbgmb/2025/v17i5462
Allium cepa test was employed to evaluate genotoxic and cytotoxic potentials of cornsilk of Zea mays L. (Poacae), which is traditionally used as a remedy to various ailments. Macroscopic and microscopic analyses were carried out on Allium cepa root meristem cells exposed to corns...
Open access
Research Article10.9734/ajbgmb/2025/v17i4461
Vitamin D, a secosteroid hormone synthesized in the skin via UVB exposure or obtained from dietary sources, is critical in numerous physiological processes. Its metabolism involves hepatic hydroxylation to 25-hydroxyvitamin D [25(OH)D], the main circulating form, followed by rena...
Open access
Research Article10.9734/ajbgmb/2025/v17i4460
Nanopore sequencing represents a paradigm shift in how we read and interpret the genetic and epigenetic information of living organisms. Unlike traditional sequencing methods that rely on amplification and fragmentation, nanopore sequencing enables the direct, real-time analysis...
Open access
Research Article10.9734/ajbgmb/2025/v17i4459
U.M. Okezie, C.I. Chimezie, N.J. Okonkwo-Uzor, V.U. Chigozie, O.G. Tochukwu, I.N. Okpoli, M.G.U. Nwaneri, J. E. Achilonu, O.B. Ifeagwu, C.J. Ikem, C.C. Onwuzuligbo & S.H. Buzugbe·Asian Journal of Biochemistry, Genetics and Molecular Biology·2025
Microbial chemodiversity of bioactive secondary metabolites remains largely unexplored for use as new antimicrobial agents. Current advances employed to exploit this plethora of bioactive compounds from microbes are focused on the stimulation of physiological processes that induc...
Open access
Research Article10.9734/ajbgmb/2025/v17i4458
Peptic ulcer disease (PUD) is a significant gastrointestinal disorder that affects millions of people worldwide, imposing substantial burden on individuals, healthcare systems and economies. The available treatment options are not devoid of attendant sequalae. The search for less...
Open access
Research Article10.9734/ajbgmb/2025/v17i4457
This review aims to examine the use of Mitracarpus scaber and Ageratum conyzoides in the traditional management of eczema in Nigeria, with an emphasis on their bioactive compounds. Various medicinal plants are used globally in the treatment of different skin diseases such as ecze...
Open access
Research Article10.9734/ajbgmb/2025/v17i4456
Aims: The study aimed to evaluate the proximate and mineral composition and identify bioactive compounds in the methanol leaf extract of Anthocleista vogelii using gas chromatography-mass spectrophotometer (GC-MS analysis), with a focus on its potential antioxidant, antimicrobial...
Open access
Research Article10.9734/ajbgmb/2025/v17i4455
The many pharmacological potentials of Stachytarpheta cayennensis (L.C. Rich) Vahl, (Verbenaceae), commonly called blue snakeweed and its use in traditional medicine in Nigeria such as in the treatment of hypertension, diabetes, mental illness and infections, could position it as...
Open access
Research Article10.9734/ajbgmb/2025/v17i4454
The use of synthetic drugs in the treatment of infertility is quite expensive and has shown to produce some adverse effects. Natural remedy such as the use of plants is recommended because they pose little or no side effects. This present work is on Impact of Tiger nuts and Date...
Open access
Research Article10.9734/ajbgmb/2025/v17i4453
Background: Colorectal cancer is a multifaceted disease with complex molecular mechanisms influencing its onset and progression. CRC has been observed to exhibit familial clustering patterns since the early 1900s. Like the majority of cancers, colorectal cancer can develop as a r...
Open access
Research Article10.9734/ajbgmb/2025/v17i4452
Background: Gastric ulcer, a disruption of the normal gastric mucosal integrity, poses a significant clinical challenge, necessitating the exploration of novel therapeutic strategies. Aim: This study investigated the potential gastroprotective effects of atorvastatin, a statin wi...
Open access
Research Article10.9734/ajbgmb/2025/v17i3451
Glycogen synthase kinase-3 (GSK-3) has been known to regulate various cellular and metabolic processes, including neuronal plasticity. Dysregulation of the GSK-3β isoform leads to the development of various neurological disorders such as Alzheimer’s, Parkinson’s, and Huntington’s...
Open access
Research Article10.9734/ajbgmb/2025/v17i3450