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All published articles 521

Bambara Groundnut (Vigna subterranea) Condiment Extract Reversed Diarrhoeal Condition in Male Wistar Rats

Olanipekun, O. T., Akinloye, O. A. & Soetan, K. O. · Asian Journal of Research in Biochemistry · 2024

Aims: The goal of the investigation is to verify the anti-diarrhoeal properties of bambara groundnut seed condiment. Study Design:  The study involved thirty male Wistar rats divided into five groups. Rats in groups 2, 3, and 4 received different dosages of the methanol extract o...

Open access Research Article 10.9734/ajrb/2024/v14i1275

Anti-Arthritic, Anti-Inflammatory, Thrombolytic, Membrane Stabilizing, Antifungal and Cytotoxic Activity of Polyscias scutellaria Leaf Extract: An In-vitro Analysis

Jakiya Akter, Hasib K. Shomudro & Sadia A. Chowdhury · Asian Journal of Research in Biochemistry · 2024

The objective of this investigations was to evaluate in Vitro anti-arthritic, anti-inflammatory, thrombolytic, membrane stabilizing, antifungal and cytotoxic activities from the methanolic leaf extract of Polyscias scutellaria. Primary evaluation of methanolic extract of Polyscia...

Open access Research Article 10.9734/ajrb/2024/v14i1274

Molecular Epidemiology of Plasmodium falciparum Infections Using PCR-based Assays in Jos, Nigeria-cross-sectional Study

Timloh Fakdul, Shangshikmwa K. Gaknung, Mercy O. Simon, Nelson J. Nwankwo, Joel Paul, Hafsat S. Jagab, Daniel G. ThankGod, Dinci T. Davou, Mary M. Mankilik, Richard J. Kutshik, Bitrus Yakubu & Ishaya Y. Longdet · Asian Journal of Research in Biochemistry · 2024

Background: Malaria remains a significant health threat globally, with Plasmodium falciparum being the predominant and lethal parasite in Africa. Nigeria is still faced with ongoing cases of asymptomatic malaria, hindering effective control measures. Aim: The aim was to generate...

Open access Research Article 10.9734/ajrb/2024/v14i1273

Bonny Light Crude Oil Toxicity: Histopathological and Biochemical Upshots on Cardiac and Hepatocellular Tissues

Elekima, Ibioku, Chukwukere Adaeze Promise, Mboo Andy Nwojo & Ibitoroko George-Opuda · Asian Journal of Research in Biochemistry · 2024

Aim: Evaluate the acute toxicity effect of bonny light crude oil on histopathological and biochemical disrupting effects on cardiac and hepatocellular tissues. Oil spills, gas flaring, natural seeps, industrial discharge, and the destruction of ecosystems have led to ecological d...

Open access Research Article 10.9734/ajrb/2024/v14i1272

Comprehensive Review of Phytochemical Content and Applications from Cestrum nocturnum: A Comparative Analysis of Physicochemical Aspects

Md. Rockibul Islam, Shanawaz Ahmed, Sumaiya Islam Sadia, Amit Kumar Sarkar & Md. Ashraful Alam · Asian Journal of Research in Biochemistry · 2023

Introduction: The term phytochemicals are plant-produced chemicals that are generated by primary or secondary metabolism. These are chemicals of plant origin. They have biological activity. The plant Cestrum nocturnum has great medicinal value. The phytochemicals such as proteins...

Open access Research Article 10.9734/ajrb/2023/v13i4271

Insight of Oxidative Stress, Ultrastructural Transformations, and Elemental Variations in Rice Seedlings Exposed to Boron Toxicity: Unraveling the Role of Fe-SOD in Boron Tolerance

Anjana Rani & Ritika Rajpoot · Asian Journal of Research in Biochemistry · 2023

Rice (Oryza sativa L.) seedlings differing in boron tolerance were grown in hydroponics containing varying boron concentration. (as boric acid) for 8 days. Yoshida Nutrient Solution (Yoshida et al.1976) served as control, whereas 0.5 mM boron (moderately toxic) and 1.5 mM boron (...

Open access Research Article 10.9734/ajrb/2023/v13i4269

Integrating In Silico and In vitro Approaches to Screen the Antidiabetic Properties from Trachyspermum ammi leaves

M. Ganga Raju, G. Shanthi Priya, N. V. L. Suvarchala Reddy V. & M. Sushma Reddy · Asian Journal of Research in Biochemistry · 2023

AIM: The purpose of this study was to explore the possible mechanisms through which Trachyspermum ammi may be beneficial in managing diabetes by in vitro methods and to predict the potential bioactive constituent/s responsible for its anti-diabetic activity through in silico dock...

Open access Research Article 10.9734/ajrb/2023/v13i4268

Evaluation of the Antioxidant Activity of Aqueous and Hydro-Ethanolic Extracts of Ficus capensis, Newbouldia laevis and Carpolobia lutea

Jean François Sibri, Joël Akakpo-Akue, Obou Constantin Okou & Tatiana Kangah Mireille Kple · Asian Journal of Research in Biochemistry · 2023

Scientific interest in the search for natural antioxidants (secondary metabolites) in medicinal plants has increased considerably in recent years, as free radicals are at the root of many diseases. The aim of this study was to evaluate the antioxidant activity of aqueous and hydr...

Open access Research Article 10.9734/ajrb/2023/v13i4267

Determination of Anti-oxidant Activity of Ethanol, Ethyl acetate, Hexane, and Aqueous Extracts of Sri Lankan Traditional Poly-herbal Formula Nāgarādi Panchakaya

Waratenne P. R., Jayasiri A. P. A. & Manuha I. M. · Asian Journal of Research in Biochemistry · 2023

Natural products are the good source of natural antioxidants. Nāgarādi panchakaya is a well-known poly-herbal formula prescribed specially for upper respiratory tract diseases by Sri Lankan Ayurveda medical practitioners. The name implies that it contains five herbal ingredients...

Open access Research Article 10.9734/ajrb/2023/v13i4266

Effects of Seed of Different Mango Cultivars in Triton X-100 Induced Hyperlipdemic Rats

Maryann Nonye Nwafor, Ikimi Charles German, Emenike Benjamin Amadi, Abba Babandi, Asadu Chidinma Lilian & Whyte Jim Alalibo · Asian Journal of Research in Biochemistry · 2023

Hyperlipidemia is the most prevalent indicator for susceptibility to atherosclerotic heart diseases. The present study investigated the hypolipidemic potential of Mangifera haden, Mangifera pirie and combined extracts of Mangifera haden and Mangifera pirie seeds in Triton X-100 i...

Open access Research Article 10.9734/ajrb/2023/v13i3265

Effect of Allium cepa (Onion) Bulb and Annona muricata (Soursop) Pulp Juices on Body Weight, Prostate Weight, Selected Hormones and Prostate-Specific Antigen (PSA) in Testosterone and Oestradiol-Induced Benign Prostatic Hyperplasia in Albino Rats

Ibegbulem C. O., Ujowundu C. O., Ukairo D. I. & Ihejieto H. A. · Asian Journal of Research in Biochemistry · 2023

Aim: This study investigated the effect of soursop pulp and onion bulb juice samples on body weight, prostate weight (PW), percentage prostate increase inhibition (PPII), dihydrotestosterone (DHT), testosterone (T), prolactin and PSA levels in testosterone and oestradiol-induced...

Open access Research Article 10.9734/ajrb/2023/v13i3264

UV Spectrophotometric Quantification of Sudan-IV Dye in Palm Oil from Major Markets of Benin Metropolis

N. U. Asiriuwa, I. O. Akpose, E. A. Okogbenin, O. B. Imoisi, D. C. Onyia, T. Okunwaye, I. L. Gold, J. U. Obibuzor & H. Anemene · Asian Journal of Research in Biochemistry · 2023

The deficit in the supply of palm oil in Nigeria over the years has been met in part through smuggling of the product from different sources into the Nigerian market by marketers of which some of the products have been reported to be adulterated with azo dyes. The aim of this stu...

Open access Research Article 10.9734/ajrb/2023/v13i3263

Membrane Stabilization, PhospholipaseA2, Albumin Denaturation, Protease Inhibition, as Viable Mechanisms for the Anti-Inflammatory Effects of Methanol Extract of Rauvolfia vomitoria Afzel Leaves

Ugwu Obiora Celestine, Asogwa Felix Keneolisa, Ukpabi-Ugo Jacinta Chigozie, Asadu Chidimma Lilian, Ali Ibeabuchi Jude, Okonkwo Raymond Maduabuchi, Ugwoke Faith Ifeanyi, Offiah Raymond Ogbonna, Obasi Uchenna Emmanuel & Anosike Chioma Assumpta · Asian Journal of Research in Biochemistry · 2023

Background: The body uses inflammation as a defence mechanism to eliminate harmful stimuli like germs, damaged cells, or irritants and to initiate the healing process. However, the ongoing discovery of several medicinal plants and the testing of their bioactivity to produce infor...

Open access Research Article 10.9734/ajrb/2023/v13i3260

Antioxidant Properties Evaluation of Trunk's Barks of 10 Plants used in Traditional Medicine against Hepatic Pathologies

Kadiatou Tata Traoré, Nogma Ernest Sombie, Nouhoun Nignan, Gilchrist A. L. Boly, Leïla M. E. W. Kabré, Adjaratou Coulibaly, Constantin Boladé Atchadé, Salfo Ouédraogo, André Tibiri, Sylvin Ouédraogo & Noufou Ouedraogo · Asian Journal of Research in Biochemistry · 2023

Aims: Herbal remedies are known for their anti-inflammatory and antioxidant properties. The aim of this study was to evaluate the antioxidant activities of the aqueous extracts of the bark of the trunk of 10 medicinal plants used in traditional medicine for the management of hepa...

Open access Research Article 10.9734/ajrb/2023/v13i3261

Microvascular Complications Associated with Advanced Glycation End Products in Diabetes

N. V. L. Suvarchala Reddy, M. Ganga Raju, Jyothi Papani & Edunoori Keerthana · Asian Journal of Research in Biochemistry · 2023

Diabetes is a frequent metabolic complaint associated with increasing blood sugar levels, it also has a connection to long- term vascular problems that can damage blood vessels, urinary tract, sight, and neurons. By adding amino acid breakdown and ultimately accumulating complex...

Open access Research Article 10.9734/ajrb/2023/v13i3262