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All published articles 499

Effects of Aqueous Stem Bark Extract of Stereospermum kunthianum on Carbon Tetrachloride - Induced Hepatotoxicity in Rats

Mahmoud Suleiman Jada, Mohammed Aliyu Sulaiman & Muktar Abdulmalik · Asian Journal of Research in Biochemistry · 2021

Aim: This study is aimed at evaluating the effects of the aqueous stem bark extract of Stereospermum kunthianum on CCl4-induced hepatotoxicity in rats. Methodology: Analysis of qualitative phytochemical components and antioxidant activity were carried out. Experimental rats were...

Open access Research Article 10.9734/ajrb/2021/v8i330183

Toxicological Evaluation and Possible Reversal of Diabetic Toxicological Complications by PHF5 an Antidiabetic Herbal Formula in Wistar Albino Rats

Egba Simeon Ikechukwu, N. Okafor Polycarp, E. Mbah Patricia, C. Ikechukwu Gavin, C. Omeoga Humphrey & W. Eze Chukwuka · Asian Journal of Research in Biochemistry · 2021

Aim: Medicinal potentials of herbs can be amplified greatly through synergism in a poly-herbal formulations. Toxic propensities of a plant can be masked out in poly-herbal preparations thus enhancing effectiveness. The aim of this study was to evaluate the potential toxicological...

Open access Research Article 10.9734/ajrb/2021/v8i330182

Study the Protective Effect of Ginger against the Toxicity of Dimethoate on Hormones in Rabbits

Sara M. Elgazwi, Fayrouz A. Khaled & Manal F. Alsanous · Asian Journal of Research in Biochemistry · 2021

Organophosphorus insecticides have been widely classified as a health dangerous and high toxicity compounds due to their widespread use and release into the environment. Ginger (Zingiber officinale) has been used as a medicinal plant since antiquity and is known to play diverse b...

Open access Research Article 10.9734/ajrb/2021/v8i330181

Protective Potential of Lycopene Enriched Tomato Extract against Dexamethasone Induced Hepatic and Renal Damage in Mice

A. Koul, J. Kaur & N. A. Chugh · Asian Journal of Research in Biochemistry · 2021

Aim: The present study was carried out to determine the protective potential of Lycopene enriched tomato extract (LycT) against hepatic and renal damage caused in mice by dexamethasone administration. Study Design: Male LACA mice were randomly divided into four treatment groups (...

Open access Research Article 10.9734/ajrb/2021/v8i330180

Plant Metabolomics: An Overview

Ramesh Londonkar & M. M. Kesaralikar · Asian Journal of Research in Biochemistry · 2021

The term metabolomics was coined by Oliver and his group in 1998. It is a study of biochemical profile and regulation of functions in whole organism by analyzing a metabolite pool present in organism. Researchers believe that more than 400,000 plant species exist worldwide. Total...

Open access Research Article 10.9734/ajrb/2021/v8i230179

In vivo and In vitro Antioxidant Activities of Aqueous and Ethanol Stem Bark Extracts of Vitex doniana on Doxorubicin-induced Oxidative Stress in Rats

Mohammed Aliyu Sulaiman, Daniel Dahiru, Mohammed Auwal Ibrahim & Ahmed Ibrahim Hayatu · Asian Journal of Research in Biochemistry · 2021

Background: Oxidative stress is involved in the pathogenesis of hypertension, myocardial ischemia-reperfusion injury, atherosclerosis, muscular dystrophy, aging and other associated diseases. Vitex doniana is used in Adamawa, northern Nigeria to treat oxidative stress associated...

Open access Research Article 10.9734/ajrb/2021/v8i230178

Determining Relative Percentage Change as a New Metrics in Scaling and Root Planning Therapy Outcome in Patients with Chronic Periodontitis

Abdul Samad Aziz, Rahul Kale, Madhav Govind Kalekar & Adinath Narayan Suryakar · Asian Journal of Research in Biochemistry · 2021

Aims: To quantify the relative percentage change in the patients with periodontitis after employing the scaling and root planning (SRP) therapy and determine the association in the improvements in clinical parameters of biochemical oxidative stress (OS) markers, total antioxidant...

Open access Research Article 10.9734/ajrb/2021/v8i230177

Alstonia boonei Leaf Mitigated Deleterious Effects of Experimental Type-II-Diabetes-Mellitus against Pancreatic and Neurocognitive Functions

Violet Olubunmi Falusi, Sunday Oluwayomi, Bamidele Imoukhuede & Gideon Oludare Oladipo · Asian Journal of Research in Biochemistry · 2021

The search for prompt, less toxic and economically affordable medical therapy has facilitated the increased investigation into the therapeutic potentials and applications of plants samples against common tropical ailments. This study was designed to investigate the reported link...

Open access Research Article 10.9734/ajrb/2021/v8i230176

Recent Studies on the Therapeutic and Prophylactic Effect of Some Agents on Experimental Induced Parkinson Disease Models Review

I. M. Hassan & A. M. Abdullahi · Asian Journal of Research in Biochemistry · 2021

Neurodegeneration include disease of the central nervous system (CNS) such as Parkinson’s disease (PD). The sign of this disease include destruction of dopaminergic neuronal cells. Main causes of this disease are unknown, but several studies reported polygenic causes. These inclu...

Open access Research Article 10.9734/ajrb/2021/v8i230175

Quantitative Determination of Biochemical Constituents of the Wild Food Plant Talinum triangulare (Jacqu) Wild (Big Purslane)

Florent Biduaya Mukeba, Archil Ndub Ilunga, Prince Bofati Ilonga, Gédéon Ngiala Bongo, Myriam Ngondo Mukadi, Koto-Te-Nyiwa Ngbolua, Johnny Bopopi Mukoko, Nadège K. Ngombe, Paulin Kapepula Mutwale & Franck Kinungi Banzola · Asian Journal of Research in Biochemistry · 2021

The Democratic Republic of the Congo is one of the major biodiversity hotspot in the world. Wild edible plants (WEPs) are widely consumed as part of daily diet by the local people and are part of their traditional culture and food habit. The T. triangulare species is a non-conven...

Open access Research Article 10.9734/ajrb/2021/v8i130174

Physico-Chemical Properties of Purified Carboxylesterase from the Seeds of Tamarindus indica

S. Kantharaju & M. Mylarappa · Asian Journal of Research in Biochemistry · 2021

The present work is focus on physical and chemical properties of purified Carboxylesterase using the Seeds of Tamarindus Indica.The esterases are extracted from the germinating tamarind seeds using 50 mM phosphate buffer, pH 7 and purified. The Km with α-naphthyl acetate, β-napht...

Open access Research Article 10.9734/ajrb/2021/v8i130173

In-vitro Anti-lipid Peroxidation and Other Antioxidant Potentials of Gongronema latifolium Leaf Extract

Tebekeme Okoko & Daniel I. Silas-Olu · Asian Journal of Research in Biochemistry · 2021

Gongronema latifolium is a herbaceous plant consumed as a traditional folk medicine. The aim of this work is to evaluate the anti-lipid peroxidation activity and other antioxidant effects of the plant leaf extract of Gongronema latifolium using various in vitro models. Lipid pero...

Open access Research Article 10.9734/ajrb/2021/v8i130172

Analysis of Bioactive Chemical Compounds of Leaves Extracts from Tamarindus indica Using FT-IR and GC-MS Spectroscopy

Mansour Abdulnabi H. Mehdi, Abdul-hakim M. A. Al- Alawi, Ahmed Zain A. Thabet, Fadel Y. S. Alarabi, Gozif Mohammed N. Omar & Vidya Pradhan · Asian Journal of Research in Biochemistry · 2021

Tamarindus indica is one of the medicinal plants used in the treatment of various diseases traditionally. Aims: This study was conducted to identify the phytochemical constituents of T. indica leaf extracts. Methods: Using Fourier-transform infrared spectroscopy (FT-IR) and gas c...

Open access Research Article 10.9734/ajrb/2021/v8i130171

Comparative Analysis of Nutrients Content and Characterization of Oil from Two Varieties of Tiger Nut (Cyperus esculentus)

A. M. Gadanya, M. Y. Abubakar, F. U. Maigari, L. Mudassir & S. M. Abubakar · Asian Journal of Research in Biochemistry · 2021

Background: Tiger nut (Cyperus esculentus) belong to the family of Cyperaceae and the order of Commelinalis. It has been existing for more than 4,000 years ago. Objective: To determine the nutritional composition (protein, fat, fiber, ash, moisture and carbohydrate) of nut, to ex...

Open access Research Article 10.9734/ajrb/2021/v8i130170

Evaluation of Bactericidal and Fungicidal Efficacy of Strychno spotatorum Linn. (Nirmali) Seeds

Chandiran Sharmila, Rajendiran Selvam & Sorimuthu Pillai Subramanian · Asian Journal of Research in Biochemistry · 2021

Aim: Diseases due to pathogenic microbes pose a great burden on human health and they have been correlated with socioeconomic, environmental, and ecological factors. The threat due to infectious diseases is further intensified by the continued emergence of new and multidrug resis...

Open access Research Article 10.9734/ajrb/2021/v8i130169