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All published articles 521

Recent Studies on the Therapeutic and Prophylactic Effect of Some Agents on Experimental Induced Parkinson Disease Models Review

I. M. Hassan & A. M. Abdullahi · Asian Journal of Research in Biochemistry · 2021

Neurodegeneration include disease of the central nervous system (CNS) such as Parkinson’s disease (PD). The sign of this disease include destruction of dopaminergic neuronal cells. Main causes of this disease are unknown, but several studies reported polygenic causes. These inclu...

Open access Research Article 10.9734/ajrb/2021/v8i230175

Quantitative Determination of Biochemical Constituents of the Wild Food Plant Talinum triangulare (Jacqu) Wild (Big Purslane)

Florent Biduaya Mukeba, Archil Ndub Ilunga, Prince Bofati Ilonga, Gédéon Ngiala Bongo, Myriam Ngondo Mukadi, Koto-Te-Nyiwa Ngbolua, Johnny Bopopi Mukoko, Nadège K. Ngombe, Paulin Kapepula Mutwale & Franck Kinungi Banzola · Asian Journal of Research in Biochemistry · 2021

The Democratic Republic of the Congo is one of the major biodiversity hotspot in the world. Wild edible plants (WEPs) are widely consumed as part of daily diet by the local people and are part of their traditional culture and food habit. The T. triangulare species is a non-conven...

Open access Research Article 10.9734/ajrb/2021/v8i130174

Physico-Chemical Properties of Purified Carboxylesterase from the Seeds of Tamarindus indica

S. Kantharaju & M. Mylarappa · Asian Journal of Research in Biochemistry · 2021

The present work is focus on physical and chemical properties of purified Carboxylesterase using the Seeds of Tamarindus Indica.The esterases are extracted from the germinating tamarind seeds using 50 mM phosphate buffer, pH 7 and purified. The Km with α-naphthyl acetate, β-napht...

Open access Research Article 10.9734/ajrb/2021/v8i130173

In-vitro Anti-lipid Peroxidation and Other Antioxidant Potentials of Gongronema latifolium Leaf Extract

Tebekeme Okoko & Daniel I. Silas-Olu · Asian Journal of Research in Biochemistry · 2021

Gongronema latifolium is a herbaceous plant consumed as a traditional folk medicine. The aim of this work is to evaluate the anti-lipid peroxidation activity and other antioxidant effects of the plant leaf extract of Gongronema latifolium using various in vitro models. Lipid pero...

Open access Research Article 10.9734/ajrb/2021/v8i130172

Analysis of Bioactive Chemical Compounds of Leaves Extracts from Tamarindus indica Using FT-IR and GC-MS Spectroscopy

Mansour Abdulnabi H. Mehdi, Abdul-hakim M. A. Al- Alawi, Ahmed Zain A. Thabet, Fadel Y. S. Alarabi, Gozif Mohammed N. Omar & Vidya Pradhan · Asian Journal of Research in Biochemistry · 2021

Tamarindus indica is one of the medicinal plants used in the treatment of various diseases traditionally. Aims: This study was conducted to identify the phytochemical constituents of T. indica leaf extracts. Methods: Using Fourier-transform infrared spectroscopy (FT-IR) and gas c...

Open access Research Article 10.9734/ajrb/2021/v8i130171

Comparative Analysis of Nutrients Content and Characterization of Oil from Two Varieties of Tiger Nut (Cyperus esculentus)

A. M. Gadanya, M. Y. Abubakar, F. U. Maigari, L. Mudassir & S. M. Abubakar · Asian Journal of Research in Biochemistry · 2021

Background: Tiger nut (Cyperus esculentus) belong to the family of Cyperaceae and the order of Commelinalis. It has been existing for more than 4,000 years ago. Objective: To determine the nutritional composition (protein, fat, fiber, ash, moisture and carbohydrate) of nut, to ex...

Open access Research Article 10.9734/ajrb/2021/v8i130170

Evaluation of Bactericidal and Fungicidal Efficacy of Strychno spotatorum Linn. (Nirmali) Seeds

Chandiran Sharmila, Rajendiran Selvam & Sorimuthu Pillai Subramanian · Asian Journal of Research in Biochemistry · 2021

Aim: Diseases due to pathogenic microbes pose a great burden on human health and they have been correlated with socioeconomic, environmental, and ecological factors. The threat due to infectious diseases is further intensified by the continued emergence of new and multidrug resis...

Open access Research Article 10.9734/ajrb/2021/v8i130169

Inhibitory Activity of β-lactamases by Hydro-Ethanolic Extracts of Harungana madagascariensis, a Plant of the Ivorian Pharmacopoeia

Toty Abalé Anatole, Aka Ayebe Edwige, Guedé Kipré Bertin, Konan K. Fernique, Adrien Jehaes, N. Guessennd, Otokoré D. Albert, M. Dosso & M. Galleni · Asian Journal of Research in Biochemistry · 2020

Infection due to multi-resistant bacteria is a public health concern. Unfortunately, the prospect of developing new antibiotics seem not to be on the horizon. Faced with this impasse, medicinal plants could be an alternative for the development of new molecules. The aim of this s...

Open access Research Article 10.9734/ajrb/2020/v7i430168

Association between TP53 and MDM2 Gene Polymorphisms and Risk of Hepatocellular Carcinoma in Hepatitis C Virus among Egyptian Populations

Ahmed Mohamed Zaky, Shaden Muawia Hanafy, Magdy Mamdouh El- Bordiny & Reham Abdel Haleem Abu El- Wafa · Asian Journal of Research in Biochemistry · 2020

Background: The Murine double minute 2 (MDM2) gene is overexpressed in several human tumors. The oncogenic potential of MDM2 is partially explained by inhibition of the activity of the tumor suppressor protein P53 (negative regulator of the P53 tumor suppressor protein). A single...

Open access Research Article 10.9734/ajrb/2020/v7i430159

Physicochemical and Microbial Evaluation of Selected Residential Borehole Water Samples in Awka, Anambra State, Nigeria

Victor Henry Azubuike Enemor, Precious Ebuka Okeke & Uchechukwu Chibuzo Ogbodo · Asian Journal of Research in Biochemistry · 2020

Water is very important to the existence of humans though could also serve as vehicle for pathogenic organisms and dangerous organic and inorganic matters. The physicochemical and microbial analyses of selected borehole water samples in Awka residential areas were conducted with...

Open access Research Article 10.9734/ajrb/2020/v7i430156

Comparative Study on the Protective Effect of Zinc Nanoparticle and Zinc Supplement on Carbamazepine Induced Reproductive Damage in Male Albino Rats

Auwal Balarabe Bello, Mudassir Lawal & A. Muhammad Hisbullahi · Asian Journal of Research in Biochemistry · 2020

Aim: The aim of this study is to compare the protective effect of zinc nanoparticle and zinc supplement against carbamazepine induced reproductive changes in male Albino rats. Study Design: In this experiment, 60 Male albino rats were used which are divided into six groups of 10...

Open access Research Article 10.9734/ajrb/2020/v7i430157

Electrolyte Concentrations and Liver Enzymes in Car Spray Painters Exposed to Car Spray Paints within Port Harcourt Metropolis, Rivers State, Nigeria

Ibiene Sarah Kalio, O. Onwuli Donatus, Abel Callum Ndubuisi & Obisie-eke Godgift · Asian Journal of Research in Biochemistry · 2020

Aim: To determine the effect of car spray paint on electrolyte concentrations (sodium, potassium, bicarbonate and chloride), Anion gap, Total Protein, Albumin, liver enzymes (Alanine amino transferase and Aspartate amino transferase) of car spray painters. Place of Study:  The st...

Open access Research Article 10.9734/ajrb/2020/v7i430155

Effect of Aqueous Extract of Costus afer Stems on the Liver and Cardiac Enzymes Activities of High Fat Diet Induced Hyperlipidemic Rats

Anyiam C. Chioma, Anyiam. C. Albert, Essien, E. Bassey & Danladi G. Jeremiah · Asian Journal of Research in Biochemistry · 2020

Aim: The present study was carried out on the effect of aqueous extract of Costus afer stems on the liver and cardiac enzymes activities of diet induced hyperlipidemic rats. Methodology: Wistar albino male rats (100-135g) were randomly distributed into 7 groups of 12 rats each. G...

Open access Research Article 10.9734/ajrb/2020/v7i430153

Chemical Profile of the Stem Extract of Costus afer (Bush Cane) from Imo State in Nigeria

Anyiam C. Chioma, Anyiam C. Albert & Anozie J. Kenechukwu · Asian Journal of Research in Biochemistry · 2020

Aim: The aim of the study was to investigate the chemical profile of the stem extract of Costus afer (Bush cane). Methodology: Fresh stems of Costus afer were obtained from Obizi in Ezinihitte Mbaise Local Government Area of Imo State. The stem extract of Costus afer a medicinal...

Open access Research Article 10.9734/ajrb/2020/v7i430154

Determination of the Fermentation Parameters of an Artisanal Beer Based on Wax and Honey in the North of Côte d'Ivoire

Karamoko Detto, Fagbohoun Jean Bedel, Moroh Jean-Luc Aboya, Ouattara Gnénépari Odjo Mahoua & Djè Koffi Marcellin · Asian Journal of Research in Biochemistry · 2020

The aim of this study is to evaluate some microbiological and physicochemical parameters during the production of artisanal beer based on honey and beeswax. Samples were collected at various critical points during the production process. The load of mesophilic aerobic germs and y...

Open access Research Article 10.9734/ajrb/2020/v7i430152