Background: Plant seeds are rich in nutrients and antinutrients which interfere with bioavailability of minerals. Objective: This research was aimed at evaluating the proximate, anti-nutrients and minerals compositions and estimation of relative mineral bioavailability of Aframom...
Open access
Research Article10.9734/ajrb/2020/v7i130129
Background: Breast cancer (BC) is the most common cause of malignancy in females all over the world. Continuous scientific research for the discovery of new markers helping is a cornerstone for early disease detection and proper management. Aim of the Study: This study aimed to e...
Open access
Research Article10.9734/ajrb/2020/v7i130128
Background: Neopterin is a proinflammatorymarker which participates in cell-mediated immunity, and its elevated concentrations declare the presence of interferon-γ in body fluids. In thisstudy, neopterin concentrations were determined in patients with chronic hepatitis C virus (H...
Open access
Research Article10.9734/ajrb/2020/v6i430127
The aim of this study was to compare the minerals, heavy metals and amino acids compositions of the seeds and juice of Cucumis metuliferus. The minerals and heavy metals content were evaluated using FS240AA agilent atomic absorption spectrometer according to the method of America...
Open access
Research Article10.9734/ajrb/2020/v6i430126
The Garcinia mangostana Linn, a medicinal plant commonly used in Southeast Asia. The crude extract and isolated metabolites were used to evaluate its potential anti-cancer activity which was compared to methotrexate (MTX) in cervical cancer cell line. The present study involved i...
Open access
Research Article10.9734/ajrb/2020/v6i430125
Aim: This study was aimed to evaluate the effect of methanol extract of Napoleonae imperialis leaves against methotrexate renal damage in albino rats. Methodology: Thirty (30) male albino rats of mean weight 130 g were used for this study. The animals for the study were grouped i...
Open access
Research Article10.9734/ajrb/2020/v6i430124
Aim: In this study, the methanol stem bark extract of Detarium microcarpum was evaluated for sub-chronic, biochemical and histopathological studies. Methodology: Sub-chronic toxicity studies was investigated in rats administered with 35, 70 and 140 mg/kg doses of the extract oral...
Open access
Research Article10.9734/ajrb/2020/v6i430123
Objective: This study is to determine the changes in liver function enzymes in P. falciparum-infected patients in Ajeromi ifelodun area of Lagos, Nigeria by examining changes in some liver enzymes: Aspartate Transaminase (AST), Alanine Transaminase (ALT) and Alkaline phosphatase...
Open access
Research Article10.9734/ajrb/2020/v6i330120
Aim: The present study was carried out to investigate the antimicrobial, cytotoxic, and anti-inflammatory activities of aqueous stem extract of Loranthus micranthus (African mistletoe) plant. Methods: The Disc agar diffusion method was used for the antimicrobial susceptibility te...
Open access
Research Article10.9734/ajrb/2020/v6i330119
Ashrafuzzaman ., Ekhlass Uddin, Raisul Islam, Nur Amin Bitu, Saddam Hossain, Nasir Uddin, Md. Mahasin Ali, Ali Asraf, Faruk Hossen, Masuqul Haque & Kudrat- E-Zahan·Asian Journal of Research in Biochemistry·2020
Antibiotic resistance has been growing at an alarming rate and consequently the activity of antibiotics against Gram-negative and Gram-positive bacteria has dropped dramatically day by day. In this sense there is a strong need to synthesis new substances that not only have good f...
Open access
Research Article10.9734/ajrb/2020/v6i330118
Giselly Maria de Sá Santana, Lidiane Pereira de Albuquerque, Emmanuel Viana Pontual, Luanna Ribeiro Santos Silva, Jaciana dos Santos Aguiar, Ana Maria Mendonça de Albuquerque Melo, Thiago Henrique Napoleão & Patrícia Maria Guedes Paiva·Asian Journal of Research in Biochemistry·2020
Background: Biomphalaria glabrata is an intermediate host for the larvae of Schistosoma mansoni, which is distributed widely in the tropics. B. glabrata control is important to minimize the spread of schistosomiasis and natural compounds have been sought for use against this dise...
Open access
Research Article10.9734/ajrb/2020/v6i330116
Nonsteroidal anti-inflammatory drugs are associated with an increase in cardiovascular events despite its uses in the therapeutic agent for the management of long- and short-term pain. Over the last years, evidence has accumulated showing that oxidative stress plays an important...
Open access
Research Article10.9734/ajrb/2020/v6i330117
This study was designed to evaluate the effect of aqueous extract of Citrullus lanatus (water melon) seeds on alloxan induced-diabetic wistar rats. The Wistar rats were grouped into 11 of 3 rats in each. Groups 2-11 received single dose of 120 mg/kg b.wt of alloxan monohydrate in...
Open access
Research Article10.9734/ajrb/2020/v6i230115
Aim: This study investigates toxicological effect of biodiesel smokes on cellular system of albino rats. Study Design: Biodiesel was blended with fuel diesel at 100, 75, 50, and 25% v/v. Rats were exposed to each flame for 120 seconds daily over a period of ten days. Place and Du...
Open access
Research Article10.9734/ajrb/2020/v6i230114
Background: Many studies have reported the lipid-lowering effect of the Garcinia kola seed in experimental animals. Objective: Assessing the effect of daily intake of Garcinia kola seed on serum lipids in adult subjects. Methods: This research work was an intervention study based...
Open access
Research Article10.9734/ajrb/2020/v6i230113