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All published articles 521

Nutritional Composition of ‘Aju Mbaise’ Herbal Cocktail

T. A. Nnadiukwu, C. C. Monago- Ighorodje & L. C. Chuku · Asian Journal of Research in Biochemistry · 2020

This study was carried out to evaluate the nutritional content of ‘Aju Mbaise’ herbal mixture. The experiment involves the collection of fresh plant samples that make up ‘Aju Mbaise’ cocktail. The study was done in the Research Laboratory of the Department of Biochemistry, Facult...

Open access Research Article 10.9734/ajrb/2020/v7i230136

Evaluation of Associated Changes on Haematological Profile of Wistar Rats Fed Curcuma longa (Turmeric) Rhizome Powder

A. V. Iwueke, E. C. Chukwu, J. N. Ejekwummadu & J. A. Nwodu · Asian Journal of Research in Biochemistry · 2020

Turmeric spice has a diverse array of biological activities. The present study evaluated body weight and haematological impact of Curcuma longa (Turmeric) in male albino rats using  standard analytical methods. Twenty four healthy male albino rats were used for the study.  Result...

Open access Research Article 10.9734/ajrb/2020/v7i230135

Synthesis, Characterization and Biological Activity of a Bidentate NS Schiff Base Containing S-Benzyl Dithiocarbazate and Its Zr(IV), Sn(II) Complexes

Md. Kudrat-E- Zahan, Md. Faruk Hossen, Rausan Zamir & Md. Ali Asraf · Asian Journal of Research in Biochemistry · 2020

Zr (IV) and Sn (II) complexes were prepared with bidentate ligand, benzyl 2-(3-phenylallylidene) hydrazinecarbodithioate, derived from the condensation of S-benzyldithiocarbazate (SBDTC) with cinnamaldehyde and characterized by microanalysis, molar conductance and magnetic measur...

Open access Research Article 10.9734/ajrb/2020/v7i230134

Mitigation of Arsenic-induced Increases in Pro-Inflammatory Cytokines and Haematological Derangements by Ethanol Leaf Extract of Irvingia gabonensis

Efosa Godwin Ewere, Ngozi Paulinus Okolie, Oboso Edem Etim & Samson Adewale Oyebadejo · Asian Journal of Research in Biochemistry · 2020

Aim: To investigate the effect of ethanol leaf extract of Irvingia gabonensis (ELEIG) on sodium arsenite (SA)-induced hepatic pro-inflammatory cytokines and haematological derangements in Wistar rats. Study Design: Fifty five Wistar rats weighing between 100 g and 161 g were rand...

Open access Research Article 10.9734/ajrb/2020/v7i130132

In vivo Antioxidant Effects of Coconut (Cocos nucifera) Water Extract in Wistar Albino Rats

O. J. Mba, U. I. Edward, O. A. Aja, I. E. Atiaetuk & M. K. Ndukwe · Asian Journal of Research in Biochemistry · 2020

Aim: The present study was designed to investigate the invivo antioxidant effects of coconut (Cocos nucifera) water extract in wistar albino rats. Methodology: Thirty (30) male wistar albino rats of mean weight 128 g were used for the study. The animals for the study were grouped...

Open access Research Article 10.9734/ajrb/2020/v7i130131

Essential Oil Compositions of Aframomum danielli Seed (Ataiko)

Peters Dikioye Emmanuel, Blessing Minaopunye Onyegeme- Okerenta & Kojo, Sarah · Asian Journal of Research in Biochemistry · 2020

Background: Differentiation in oil quality and the volatile component of essential oils (EOs) is associated with climatic conditions, the geographical location of collection sites and other ecological and genetic factors defining its chemotypes. Objective: Hence this study was ai...

Open access Research Article 10.9734/ajrb/2020/v7i130130

Proximate, Antinutrient and Mineral Contents of Aframomum danielli (Ataiko) Seed

Peters Dikioye Emmanuel & Kojo, Sarah · Asian Journal of Research in Biochemistry · 2020

Background: Plant seeds are rich in nutrients and antinutrients which interfere with bioavailability of minerals. Objective: This research was aimed at evaluating the proximate, anti-nutrients and minerals compositions and estimation of relative mineral bioavailability of Aframom...

Open access Research Article 10.9734/ajrb/2020/v7i130129

Study of the Potential Role of Serum Neutrophil Gelatinase-Associated Lipocalin (NGAL) Levels in the Diagnosis and Prognosis of Breast Cancer in Egyptian Females "A Case-Control Study"

F. Z. Mohammed, Lamis Gamal, Mohamed Farouk Mosa & I. M. El- deen · Asian Journal of Research in Biochemistry · 2020

Background: Breast cancer (BC) is the most common cause of malignancy in females all over the world. Continuous scientific research for the discovery of new markers helping is a cornerstone for early disease detection and proper management. Aim of the Study: This study aimed to e...

Open access Research Article 10.9734/ajrb/2020/v7i130128

Neopterin as a Predictor of Response to Pegylated Interferon Therapy in Egyptian Patients with Chronic Hepatitis C Virus

Heba Gamal Abdelaziz, Tamer Mahmoud El- Tantawy, Hanan Abd El-Mawgoud Attia & Mayada Mosa Hamed · Asian Journal of Research in Biochemistry · 2020

Background: Neopterin is a proinflammatorymarker which participates in cell-mediated immunity, and its elevated concentrations declare the presence of interferon-γ in body fluids. In thisstudy, neopterin concentrations were determined in patients with chronic hepatitis C virus (H...

Open access Research Article 10.9734/ajrb/2020/v6i430127

Comparative Analysis of Minerals, Heavy Metals and Amino Acids Compositions of the Seeds and Juice of Cucumis metuliferus

Onuabuchi Nnenna Ani, Cosmas Ezekaibeya Achikanu & Chukwuebuka Kenechukwu Onyishi · Asian Journal of Research in Biochemistry · 2020

The aim of this study was to compare the minerals, heavy metals and amino acids compositions of the seeds and juice of Cucumis metuliferus. The minerals and heavy metals content were evaluated using FS240AA agilent atomic absorption spectrometer according to the method of America...

Open access Research Article 10.9734/ajrb/2020/v6i430126

Anti-cancer Activity of Garcinia mangostana L. and Its Derivatives in Cervical Cancer

S. V. Kirthanashri, N. Ramesh Kumar & S. Chitra · Asian Journal of Research in Biochemistry · 2020

The Garcinia mangostana Linn, a medicinal plant commonly used in Southeast Asia. The crude extract and isolated metabolites were used to evaluate its potential anti-cancer activity which was compared to methotrexate (MTX) in cervical cancer cell line. The present study involved i...

Open access Research Article 10.9734/ajrb/2020/v6i430125

Ameliorative Effect of the Methanol Extract of Napoleonae imperialis Leaves against Methotrexate-induced Renal Damage in Albino Rats

O. J. Mba, G. S. Aloh & E. N. Uhuo · Asian Journal of Research in Biochemistry · 2020

Aim: This study was aimed to evaluate the effect of methanol extract of Napoleonae imperialis leaves against methotrexate renal damage in albino rats. Methodology: Thirty (30) male albino rats of mean weight 130 g were used for this study. The animals for the study were grouped i...

Open access Research Article 10.9734/ajrb/2020/v6i430124

Biochemical and Histopathological Effect of Detarium microcarpum Stem Bark Extract in Wistar Albino Rats

Abubakar Bilyamini Mu’azu, Yusif Bello Baba & Adamu Idris Matinja · Asian Journal of Research in Biochemistry · 2020

Aim: In this study, the methanol stem bark extract of Detarium microcarpum was evaluated for sub-chronic, biochemical and histopathological studies. Methodology: Sub-chronic toxicity studies was investigated in rats administered with 35, 70 and 140 mg/kg doses of the extract oral...

Open access Research Article 10.9734/ajrb/2020/v6i430123

Changes in Liver Function Enzymes in Plasmodium falciparum Infected Malaria Patients in Ajeromi General Hospital, Lagos, Nigeria

U. O. Ozojiofor, O. O. Bankole, I. O. Adedeji & K. C. Onuh · Asian Journal of Research in Biochemistry · 2020

Objective: This study is to determine the changes in liver function enzymes in P. falciparum-infected patients in Ajeromi ifelodun area of Lagos, Nigeria by examining changes in some liver enzymes: Aspartate Transaminase (AST), Alanine Transaminase (ALT) and Alkaline phosphatase...

Open access Research Article 10.9734/ajrb/2020/v6i330120