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All published articles 521

Effect of Aqueous Stem Extract of Loranthus micranthus linn on Anti-microbial Sensitivity, Cytotoxicity, and In-vitro Anti-inflammatory Indices on Human Red Blood Cells

Chinedu E. Udekwu, Shirley Ebhohon, Raymond C. Ibeh, Henry N. Ogbonna & Ugonna D. Nwankpa · Asian Journal of Research in Biochemistry · 2020

Aim: The present study was carried out to investigate the antimicrobial, cytotoxic, and anti-inflammatory activities of aqueous stem extract of Loranthus micranthus (African mistletoe) plant. Methods: The Disc agar diffusion method was used for the antimicrobial susceptibility te...

Open access Research Article 10.9734/ajrb/2020/v6i330119

Biological Applications of Isoniazid Derived Schiff Base Complexes: An Overview

Ashrafuzzaman ., Ekhlass Uddin, Raisul Islam, Nur Amin Bitu, Saddam Hossain, Nasir Uddin, Md. Mahasin Ali, Ali Asraf, Faruk Hossen, Masuqul Haque & Kudrat- E-Zahan · Asian Journal of Research in Biochemistry · 2020

Antibiotic resistance has been growing at an alarming rate and consequently the activity of antibiotics against Gram-negative and Gram-positive bacteria has dropped dramatically day by day. In this sense there is a strong need to synthesis new substances that not only have good f...

Open access Research Article 10.9734/ajrb/2020/v6i330118

Evaluation of the Molluscicidal, Artemicidal and Cytotoxic Activities of the Lectin from Opuntia ficus-indica Cladodes (OfiL)

Giselly Maria de Sá Santana, Lidiane Pereira de Albuquerque, Emmanuel Viana Pontual, Luanna Ribeiro Santos Silva, Jaciana dos Santos Aguiar, Ana Maria Mendonça de Albuquerque Melo, Thiago Henrique Napoleão & Patrícia Maria Guedes Paiva · Asian Journal of Research in Biochemistry · 2020

Background: Biomphalaria glabrata is an intermediate host for the larvae of Schistosoma mansoni, which is distributed widely in the tropics. B. glabrata control is important to minimize the spread of schistosomiasis and natural compounds have been sought for use against this dise...

Open access Research Article 10.9734/ajrb/2020/v6i330116

Evaluation of Stress Enzymes Activities and Lipid Peroxidation in Heart Homogenates of Male Albino Rats Following the Administration of Diclofenac

Felicia Nmeazi Okwakpam, S. Abarikwu & M. O. Monanu · Asian Journal of Research in Biochemistry · 2020

Nonsteroidal anti-inflammatory drugs are associated with an increase in cardiovascular events despite its uses in the therapeutic agent for the management of long- and short-term pain. Over the last years, evidence has accumulated showing that oxidative stress plays an important...

Open access Research Article 10.9734/ajrb/2020/v6i330117

Effect of Aqueous Extract of Citrullus lanatus (Water Melon) Seeds on Alloxan Induced - Diabetic Wistar Rats

H. E. Ogbeifun, D. E. Peters & M. Monanu · Asian Journal of Research in Biochemistry · 2020

This study was designed to evaluate the effect of aqueous extract of Citrullus lanatus (water melon) seeds on alloxan induced-diabetic wistar rats. The Wistar rats were grouped into 11 of 3 rats in each. Groups 2-11 received single dose of 120 mg/kg b.wt of alloxan monohydrate in...

Open access Research Article 10.9734/ajrb/2020/v6i230115

Toxicological Effect of Biodiesel Emission Particles on Cellular System of Albino Rats

Adeyemi, Olalekan & Adeyemi, Oyeyemi · Asian Journal of Research in Biochemistry · 2020

Aim: This study investigates toxicological effect of biodiesel smokes on cellular system of albino rats. Study Design: Biodiesel was blended with fuel diesel at 100, 75, 50, and 25% v/v. Rats were exposed to each flame for 120 seconds daily over a period of ten days. Place and Du...

Open access Research Article 10.9734/ajrb/2020/v6i230114

Effect of the Garcinia kola Seed on Serum Lipids in Adult Subjects

Moutawakilou Gomina, Tarik Salifou, Gilbert Djidonou & Stanislas Zinsou · Asian Journal of Research in Biochemistry · 2020

Background: Many studies have reported the lipid-lowering effect of the Garcinia kola seed in experimental animals. Objective: Assessing the effect of daily intake of Garcinia kola seed on serum lipids in adult subjects. Methods: This research work was an intervention study based...

Open access Research Article 10.9734/ajrb/2020/v6i230113

Mineral, Fatty and Amino Acids Composition of Three Species of Mollusks (Egeria radiata, Limicolaria flammea and Viviparus contectus)

I. Felagha, M. O. Monanu & B. A. Amadi · Asian Journal of Research in Biochemistry · 2020

The present study investigates the mineral, fatty acid and amino acids composition of E. radiata,                 V. contectus and L. flammea. All samples analyzed in this study were obtained from Yenagoa in Bayelsa state of Nigeria. Mineral composition was determined by Atomic A...

Open access Research Article 10.9734/ajrb/2020/v6i230112

Effect of a Combination of Ethanol Extract of Ficus capensis and Cnidoscolus aconitifolius on Liver and Kidney Function Parameters of Phenylhydrazine-Induced Anemic Rats

Ezeigwe, Obiajulu Christian, Okpala, Chukwuemeka Obumneme, Ogbodo, Uchechukwu Chibuzo, Anwuna, Chioma Divine, Ngwu, Ogochukwu Rita & Chigbo, Chidiebere Malachy · Asian Journal of Research in Biochemistry · 2020

Background: Anemia is a condition in which there is a reduced number of red blood cells or haemoglobin and iron concentration in the body thereby leading to a decreased capacity of the blood to carry oxygen to the body tissues. Objectives: The study was designed to investigate th...

Open access Research Article 10.9734/ajrb/2020/v6i230111

Utilization of Telang Leaf Meal as Antioxidant Source in Feed of Tilapia (Oreochromis niloticus)

Yuli Andriani, Muhammad Donny Ericson, Junianto . & Rosidah . · Asian Journal of Research in Biochemistry · 2020

Aims: This study aimed to determine the effective percentage of telang leaf meal on feed to increase antioxidant levels in tilapia liver feed. Study Design: A total of 12 aquariums with sizes 60 x 40 x 40 cm3and volume 96 L prepared and filled with 30 L water. Heater was installe...

Open access Research Article 10.9734/ajrb/2020/v6i130110

Nutritional Study of Processed Amygdalus communis L. Sesamum indicum and Bertholletia excelsa Nuts on Two Weeks Old Wistar Rats

Blessing M. Onyegeme-Okerenta, Omeodu Steve & Okere Peace Ijeoma · Asian Journal of Research in Biochemistry · 2020

The study evaluated the nutritional benefits of processed Almond nuts, Sesame seeds and Brazil nut on two weeks old Wistar rats. The rats were weighed and arranged into seven groups and feed for 4 weeks. Group one (control) was fed with commercial rat feed and distilled water. Gr...

Open access Research Article 10.9734/ajrb/2020/v6i130109

Effect of Manihot esculenta and Manihot utilissima Cyanide Extract on Some Biochemical Parameters of Albino Rats

Amodu Abuh, Reuben Agada & Dluya Thagariki · Asian Journal of Research in Biochemistry · 2020

Cassava roots (Manihot esculenta and Manihot utilissima) are largely consumed as staple food in African but contain a toxic compound, cyanogenic glycosides. This study evaluated the effect of Manihot esculenta and Manihot utilissima cyanide content on biochemical parameters and h...

Open access Research Article 10.9734/ajrb/2020/v6i130108

Evaluation of the Antioxidant Activity of Stalk and Fruit of Solanum aethiopicum L. (Solanaceae)

Kady Diatta, William Diatta, Alioune Dior Fall, Serigne Ibra Mbacké Dieng, Amadou Ibrahima Mbaye, Abdou Sarr & Mourchidath Adjoke Adegbindin · Asian Journal of Research in Biochemistry · 2020

Background: The use of plants for healing dates back to very remote times. Nowadays with the accession of new diseases plants are increasingly used for the formulation of new drugs able to overcome the many diseases (cancer, atherosclerosis) often caused by the disorder of the sy...

Open access Research Article 10.9734/ajrb/2020/v6i130107

Hematotoxic Effect of Water Soluble Fraction of Bonny Light Crude Oil in Wistar Albino Rats

Abraham, Chiedozie Nicholas, Godwin J. Udom & Kingsley C. Patrick-Iwuanyanwu · Asian Journal of Research in Biochemistry · 2020

This study evaluated the Hematotoxic effect of water soluble fraction (WSF) of Bonny Light Crude Oil (BLCO) in Wistar Albino rats. After preparation of the WSF and a range finding test, the Wistar albino rats were administered three concentrations (25%, 50% and 100%) of WSF of BL...

Open access Research Article 10.9734/ajrb/2020/v6i130106

In vivo Biochemical Evaluation of Some Synthesize Thiazole Derivatives Containing Coumarin Moiety as Antioxidant and Antitumor Agents

F. Z. Mohammed, Lamiaa A. A. Barakat, Emad M. Gad & N. M. Shetya · Asian Journal of Research in Biochemistry · 2019

Background: Coumarin and thiazole derivatives have been used traditionally for many centuries. Because they have anti-tumor, antioxidant activities, and induced apoptosis. Aim: The present study aims to investigate the in vivo antitumor, and antioxidant activities of potassium sa...

Open access Research Article 10.9734/ajrb/2019/v5i430104