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All published articles 521

Total Enzyme-substrate Complex Which Includes Product-destined Enzyme-substrate Complex

Ikechukwu I. Udema · Asian Journal of Research in Biochemistry · 2019

Background: There is no much interest in the determination of total enzyme-substrate complex concentration ([ES]T) which includes undissociated ES that is unaccounted for unlike the usual ES destined for transformation into free enzyme and product or substrate. The reason is spec...

Open access Research Article 10.9734/ajrb/2019/v5i430105

Morpho-functional Changes in Liver due to Long Term Consumption of Instant Noodles in Adult Wistar Rats

Ibrahim Saleh, Adjene Josiah Obaghwarhievwo, Igumbor Eunice Obiajulu & Odigie Mike Osagie · Asian Journal of Research in Biochemistry · 2019

Introduction: Food is a basic requirement for the survival of living organisms, and is also necessary for growth, development, replacement and repairs of worn-out tissues, as well as energy production for various body functions, among others. Aim: Current study investigated the h...

Open access Research Article 10.9734/ajrb/2019/v5i430103

The Experimentally Determined Velocity of Catalysis could be Higher in the Absence of Sequestration

Ikechukwu I. Udema & Abraham Olalere Onigbinde · Asian Journal of Research in Biochemistry · 2019

Background: It is not unusual to observe calculated “total” free enzyme ([E]) in enzyme catalysed reaction, but this should include total enzyme-substrate complex ([EST]) which accounts for sequestration. Objectives: 1) To show indirectly that the velocities of catalytic action c...

Open access Research Article 10.9734/ajrb/2019/v5i430098

The Organ Distribution, Characterization and Modification of Acetylcholinesterase Activity in Adult African Grasshopper: Zonocerus sp Linn.

E. A. Fajemisin, O. S. Bamidele, S. O. Ogunsola & E. A. Aiyenuro · Asian Journal of Research in Biochemistry · 2019

Aim: To determine the organ distribution and characterization of acetylcholinesterase in the adult African variegated grasshoppers – Zonocerus variegatus and Zonocerus elegans. (Zonocerus Sp. Linn) Place and Duration of the Study: The insect model: African variegated grasshoppers...

Open access Research Article 10.9734/ajrb/2019/v5i430097

Comparative Study on Effect of Chrysophyllum albidum Medicinal Plant from Crude Oil Polluted and Non-crude Oil Polluted Areas on Selected Biochemical Parameters in Rats

Grace Ekpo, Benjamin Amadi, Eze Adindu, Odey Michael & Princewill Dasimeokuna · Asian Journal of Research in Biochemistry · 2019

Comparative study on effect of Chrysophyllum albidum medicinal plant from crude oil polluted and non-crude oil polluted areas on selected biochemical parameters in rats was evaluated.  Leaves of C. albidium were collected from a botanical garden (non-crude oil polluted site) and...

Open access Research Article 10.9734/ajrb/2019/v5i430096

Antiplasmodial, Hepatic and Nephritic Effects of Fractions of Methanol Leaf Extract of Glyphaea brevis in Plasmodium berghei-Infected Mice

Tayo Micheal Anjuwon, Oluwafemi Abiodun Adepoju & Olufemi Adewale Adeniran · Asian Journal of Research in Biochemistry · 2019

This study evaluated the antiplasmodial, hepatic and nephritic effects of fractions of Glyphaea brevis methanol leaf extract in P. berghei infected mice. Mice weighing between 15-30 g were infested intraperitoneally with 0.2ml plasmodium infected blood and left for 3 hours before...

Open access Research Article 10.9734/ajrb/2019/v5i430094

The Diagnostic Value of the Glucose Curve in Individuals with and without Diabetes

Mohamed S. El-Gareb & Mohamed N. El-Naggar · Asian Journal of Research in Biochemistry · 2019

Aim: Of this study is to demonstrate the importance of glucose curve test in monitoring pre and post-meal variation in diabetic and normal individuals. Methodology: The individuals subjected to this study mainly grouped in two categories the (DM2 group) and the (Control group), t...

Open access Research Article 10.9734/ajrb/2019/v5i430095

Evaluation of Haematological Parameters in Stroke Patients in South-Western Nigeria

I. Akinlua & M. F. Asaolu · Asian Journal of Research in Biochemistry · 2019

Introduction: Stroke is a leading cause of morbidity and mortality worldwide. Atherosclerosis is a leading cause of both ischemic and haemorrhagic stroke which has been linked to chronic and acute inflammation. Variations in the biochemical status of stroke patients might be acco...

Open access Research Article 10.9734/ajrb/2019/v5i330093

The Effect of Structural Modification on the Blood Brain Barrier Permeation Properties of Allicin

Victor E. Itepu, Ogochukwu J. Umezinwa, Fidelis A. Ilukho, Difa A. Collins & Cosmas Samuel · Asian Journal of Research in Biochemistry · 2019

Allicin is found in nursery onion. Allicin is isolated from garlic (Allium sativum). Nutriceutical allicin is an organice compound gotten from garlic. It is also sourced from onions, and different species in the family Alliaceae. It was first isolated and examined in the research...

Open access Research Article 10.9734/ajrb/2019/v5i330092

Antioxidant, Hypolipidemic and Angiotensin Converting Enzyme Inhibitory Effects of Flavonoid-rich Fraction of Hyphaene thebaica (Doum Palm) Fruits on Fat-fed Obese Wistar Rats

M. A. Abdulazeez, A. Bashir, B. S. Adoyi, A. Z. Mustapha, B. Kurfi, A. Y. Usman & R. K. Bala · Asian Journal of Research in Biochemistry · 2019

Aims: This study investigated the antioxidant, hypolipidemic and angiotensin converting enzyme (ACE) inhibitory effects of flavonoid-rich fraction of H. thebaica on fat-fed obese wistar rats. Study Design: Twenty-five rats were divided into 5 groups of 5 rats each: Control (stand...

Open access Research Article 10.9734/ajrb/2019/v5i330091

Evaluation of Invertase and Amylase Activities of Latic Acid Bacteria Isolated from ‘Pupuru’ (An Indigenous African Fermented Cassava Staple Food)

B. C. Akin-Osanaiye, B. T. Azeez & I. W. Olobayotan · Asian Journal of Research in Biochemistry · 2019

Lactic acid bacteria produce lactic acid as the major end product during sugar fermentation. This study was carried out to isolate lactic acid bacteria (LAB) from pupuru; a staple cassava food. The result of the bacterial count indicated that the count ranges from 3.1 × 104 CFU/g...

Open access Research Article 10.9734/ajrb/2019/v5i330090

The State of Proteins not with Standing, Translational Velocity is Vital for their Function

Ikechukwu Iloh Udema & Abraham Olalere Onigbinde · Asian Journal of Research in Biochemistry · 2019

Background: Targeting of macromolecules by means of translational diffusion for therapeutic reason is generally of interest. But translational velocity that enables directional delivery of any molecule on target is given less attention. Objectives: The objectives of this research...

Open access Research Article 10.9734/ajrb/2019/v5i330089

Amelioration of Monosodium Glutamate-induced Testicular Damage and Infertility in Male Rats by Water Melon and Cantaloupe Seeds Extract and Juices

Shimaa El-Masry & Mai Elsayed · Asian Journal of Research in Biochemistry · 2019

Aims: Monosodium glutamate (MSG) is extensively used as food additive and flavor enhancer, there is a growing concern that this may affect the male reproductive system and fertility. The objective of this study is to investigate the effect of MSG on fertility and testes of mature...

Open access Research Article 10.9734/ajrb/2019/v5i230088

Effect of Oral Intake of Sodium Benzoate on Serum Cholesterol and Proinflammatory Cytokine (Tumor Necrosis Factor Alpha [TNF-α] and Interleukin-6 [IL-6]) Levels in the Heart Tissue of Wistar Rats

Efekemo, Oghenetekevwe, Akaninwor, Joyce Oronne & Essien, Eka Bassey · Asian Journal of Research in Biochemistry · 2019

The in vivo effect of oral administration of varying concentrations (150, 250, 500 mg/kg body wt.) of sodium benzoate (a known preservative in the food, cosmetic and pharmaceutical industry) on serum cholesterol and proinflammatory markers in heart tissue of wistar albino rats we...

Open access Research Article 10.9734/ajrb/2019/v5i230086

Theoretical Insight into Preferential Interaction Issues and Solution Structure, and Contentious Apparent Hydrated Molar Volume of Cosolute

Ikechukwu Iloh Udema & Abraham Olalere Onigbinde · Asian Journal of Research in Biochemistry · 2019

Background: There seems to be a mathematical or a conceptual error in an equation whose substitution into other equations for the determination of an apparent hydrated molar volume (V1) of a cosolute leads to an incorrect answer. Objectives: The objectives are 1) To show theoreti...

Open access Research Article 10.9734/ajrb/2019/v5i230087