Aim: This study was targeted at valuing a claim by traditional herbal practitioners that the leaf of Eriosema psoraleoides possesses a hypoglycemic and hypolipidemic property by assessing the effect of aqueous leaf extract of Eriosema psoraleoides on antihyperglycemic and hypolip...
Open access
Research Article10.9734/ajrb/2019/v4i130061
Trigonella foenum-graceum extract either alone or combined with selenium nanoparticles exhibited antitumor effect. Ehrlich ascite carcinoma (EAC) cell line and four groups of female mice were used. Solid Ehrlich carcinoma (EC) was induced by inoculation of 2.5x106 cells in left t...
Open access
Research Article10.9734/ajrb/2019/v4i130059
Aim: This study was undertaken to investigate the effect of aqueous leaf extract of Icacina trichanta on lipid profile and CCl4- induced histological changes in Wistar rats. Study Design: Liver damage was induced with CCl4 and the rats were treated with aqueous extract of Icacina...
Open access
Research Article10.9734/ajrb/2019/v4i130060
Background: The association between diabetes mellitus and inflammation is established but the use of non-steroidal anti-inflammatory drugs is not without some health risk. Aim: The study was aimed at comparing the levels of some inflammatory biomarkers in diabetic rats treated wi...
Open access
Research Article10.9734/ajrb/2019/v4i130058
The study was conducted to evaluate the vitamin and mineral compositions of leaves of Alchornea cordifolia and Thaumatococcus daniellii. Standard methods were employed to determine the vitamin and mineral compositions of plant samples. Results obtained from the study showed that...
Open access
Research Article10.9734/ajrb/2018/v3i430056
Iserhienrhien Lucky Osafanme, Sheneni Victor Duniya, Nweje-Anyalowu Paul Chukwuemeka, Oguche Mercy & Idakwoji Precious Adejoh·Asian Journal of Research in Biochemistry·2019
Aim: The haematinic activity of the aqueous extract of Lophira lanceolata leaves was investigated using rat model of phenylhydrazine-induced anaemia. Methods and Results: Red Blood Cell (RBC) count, Haemoglobin (Hb) concentration and Packed Cell Volume (PCV) were analysed as indi...
Open access
Research Article10.9734/ajrb/2019/v4i130057
Most of the currently available therapeutic agents, particularly for cardiovascular disorders and cancers are very expensive and induce some serious side effects. Some of these drugs have also become less effective due to the emergence of antibiotic resistance. There is a necessi...
Open access
Research Article10.9734/ajrb/2018/v3i430055
Aim: The aim of the study was to evaluate the effect of action bitters on some liver and renal function indices of Albino rats. Study Design: Experimental rats were divided into two groups A and B. Group A (control rats) consist of 10 rats and were not given herbal drugs while gr...
Open access
Research Article10.9734/ajrb/2018/v3i430054
Today’s developmental world needs large amount of energy. Due to the limited fossil fuel source, there is need of some alternate fuel sources among which biodiesel from vegetable oil widely practiced. There is an increasing interest in India to search for suitable low cost altern...
Open access
Research Article10.9734/ajrb/2018/v3i430053
Background and Aim: Tramadol is a potent analgesic effective in the treatment of mild to severe pains. However, the use of the drug can pose a threat to other organs and systems. Therefore, this study evaluated the effect of graded doses of tramadol on sperm profile of male albin...
Open access
Research Article10.9734/ajrb/2018/v3i429844
Aims: To study the potential genotoxicity of two polynuclear aromatic hydrocarbons (PAHs), exposed cultured human leukocytes in vitro using two types of biomarkers genotoxicity: DNA strand breaks (DNA-SB) and adduct formation (DNA-PAHs). Study Design: Human leukocytes were expose...
Open access
Research Article10.9734/ajrb/2018/v3i329837
Aim: This study aims to determine the effects of methanolic root extract of Holarrehna floribunda on the level of some serum sex hormones, follicle stimulating hormone (FSH), luteinizing hormone (LH), testosterone, estradiol, progesterone and lipid profile in Wistar rats. Mater...
Open access
Research Article10.9734/ajrb/2018/v3i329829
Heterocyclic compounds have a large spectrum of biological activities including antitumor activity. The present study describes the cytotoxic effect of newly synthesized thiazole derivative (TD2) that can prove effective antitumor activity on both in vivo and in vitro studies. Ob...
Open access
Research Article10.9734/ajrb/2018/v3i329831
Background: Thiazole nucleus–containing compounds have an antitumor efficiency against various types of cancer. Purpose: The present study was designed to determine the cytotoxic effect of newly synthesized thiazole derivative (TD1) on human cancer cell lines, in addition to eval...
Open access
Research Article10.9734/ajrb/2018/v3i229826
Aims: The present study aimed to elucidate the protective role of L-Arginine on lead – induced suppression of the pathway of heme synthesis and the toxicity of lead on testis. Methodology: The current study included two experiments; the first was carried out on two groups to foll...
Open access
Research Article10.9734/ajrb/2018/v3i229824