Aim: Taq DNA polymerase from Thermus aquaticus is a key enzyme in the field of molecular biology that has been mostly used in polymerase chain reaction (PCR). Our aim is to produce standard grade Taq DNA polymerase free from censorious impurities like DNase, DNA and other contami...
Open access
Research Article10.9734/ajrb/2018/v2i4607
Aim: The role of nutrition in lipid metabolism continues to generate a lot of research interest, especially as dyslipidaemia is implicated in a host of diseases. The work investigated the effect of ethanol extract of Curcubita pepo leaves on the lipid profile of Wister rats. Met...
Open access
Research Article10.9734/ajrb/2018/v2i4601
Aim: This study is aimed at determining the levels of some heavy metals in the water, sediment and fishes (Oreochromis niloticus, Periopthalmus koelreuteri, Micropogonias undulatus, Carassius auratus and Liza felcipinis) from new Calabar River located at Rumuolumeni Community in...
Open access
Research Article10.9734/ajrb/2018/v2i4599
Background: Azadiradita indica seed has been used in traditional system of medicine. It is known to be natural medicine with many benefits. Toxicological studies have reported that toxic effects may be related to the complex mixtures of active constituents and other chemicals whi...
Open access
Research Article10.9734/ajrb/2018/v2i4561
Two lactobacilli strains; Lactobacillus acidophilus ATCC 20079 and Lactobacillus plantarum ATCC 20179 and two bifidobacteria strains; Bifidobacterium bifidum GSGG 5286 and Bifidobacterium longum ATCC 15707 were studied their abilities to reduce the cholesterol content in vitro. I...
Open access
Research Article10.9734/ajrb/2018/v2i4540
The in vitro potential of aqueous extracts of plant leaves to inhibit pathogenic fungi was carried out. The effect of leaf extract and concentration on growth inhibition of organism I (Aspergillus flavus) in vitro revealed that a concentration of 100g/mL, Moringa oleifera leaf ex...
Open access
Research Article10.9734/ajrb/2018/v2i3535
The screening of bioactive phytochemical constituents in edible fruits and vegetable is interesting to researchers owing their benefit property on consumer’s health. Fruits are used ethnomedicinally to treat numerous diseases including metabolic and microbial diseases. They are a...
Open access
Research Article10.9734/ajrb/2018/v2i3530
Lead (Pb) is one of the environmental pollutants. There has been a serious concern in the recent past regarding natural source for protection or curing from lead. The aim of the present study is evaluation and comparing of mulberry leaves and fruits extracts in protection from le...
Open access
Research Article10.9734/ajrb/2018/v2i3525
Obesity is associated with an increased risk of metabolic syndromes such as type 2 diabetes, insulin resistance, dyslipidaemia and non-alcoholic fatty liver disease. Obesity occurs as a result of an imbalance between food intake and energy expenditure leading to excessive accumul...
Open access
Research Article10.9734/ajrb/2018/v2i3497
Background: Benign prostatic hyperplasia (BPH) is a histological disease characterised by an increased number of epithelial cells and stromal cells within the prostate gland. We investigated the effect of aqueous leaf extract of Ocimum gratissimum on BPH induced animal model. Me...
Open access
Research Article10.9734/ajrb/2018/v2i2468
Aims: Prostaglandins and Thromboxane A2 are prostanoids, with platelet aggregator and vasoconstrictor properties. This study was carried out to assess the prostaglandins and thromboxane status of patients with cardiovascular diseases in Ekiti State, Nigeria. Study Design: This i...
Open access
Research Article10.9734/ajrb/2018/v2i3487
A multitude of plants have been used extensively for the treatment of cancers throughout the world. In many parts of the world, especially in poor countries, this may be the only form of cancer therapy. Much research has been focused on the scientific evaluation of traditional a...
Open access
Research Article10.9734/ajrb/2018/v2i2462
Aim: To determine the anti-snake venom effect of crude aqueous and ethanolic extracts and separated fractions of Crinum jagus bulb on rats injected with Echis ocellatus venom. Study Design: Evaluation of LD50 of venom, anti-lethal effects of different extract preparations and the...
Open access
Research Article10.9734/ajrb/2018/v2i2455
Objective: The current research is designed to evaluate copper oxide nanoparitcles (CuO NPs) toxicity on HCT116 in vitro as well as in vivo on liver paraoxanse 1 (PON1 ) activity and serum B-cell lymphoma -2 (BCl2) in rats. Materials and Methods: The toxicological role of CuO-NPs...
Open access
Research Article10.9734/ajrb/2018/v2i2450
Objective: The study investigated the possibility of using blood groups as predictive indices for diseases associated with lipid metabolism. Methods: Lipid profiles were examined in 100 apparently healthy male (40) and female (60) subjects of different ABO blood groups aged betwe...
Open access
Research Article10.9734/ajrb/2018/v2i2424