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All published articles 521

In vitro Alpha- Amylase and Alpha- Glucosidase Inhibitory Effects of the Methanolic Leaf Extract of Ficus abutilifolia

Umma Aliyu Idris, Abdullahi Nasir, Ibrahim Hamza Kankia, Aliyu Ibrahim Yaradua, Ibrahim Usman Muhammad, Akilu Sada Abdullahi, Rukayya Lawal Gambo & Haruna Tsoho Bala · Asian Journal of Research in Biochemistry · 2025

Aim: To investigate α –amylase and α-glucosidase inhibitory effects of the methanolic leaf extract of Ficus abutilifolia In vitro. Study Design: The leaf extract was fractionated using Thin Layer Chromatography. Place and Duration of Study: Department of Biochemistry, Umaru Musa...

Open access Research Article 10.9734/ajrb/2025/v15i4413

Anti-oxidant Effects of Annona muricata Ethanol Stem Bark Extract in N-nitroso- N- Methylurea (NMU)-Induced Prostate Cancer in Albino Rats

Onyinyechi Chijioke Njoku, Chidi Uzoma Igwe, Favour Ntite Ujowundu, Chieme Sunday Chukwudoruo, Chimdi Ezichi Esonu, Raymond Chigozie Ibeh, Nnenna Chinenyenwa Osuji-kalu, Blessing Amarachi Mba, Olachi Lilian Osuagwu & Chibuike Valentine Edom · Asian Journal of Research in Biochemistry · 2025

Background: Evidence has suggested that the pathogenesis of prostatic hyperplasia and prostate cancer is closely related to the state of oxidative stress in prostate tissue. This study evaluated the anti-oxidative stress effects of A. muricata ethanol stem bark extract in N-nitro...

Open access Research Article 10.9734/ajrb/2025/v15i4412

Determination of Total Tannin Content and Antioxidant Activity of the Ethanol Extract from Senduduk Leaves (Melastoma malabathricum L.)

Epi Supri Wardi, Roslinda Rasyid, Maida Soniamarta, Yuliawati & Bastian Nova · Asian Journal of Research in Biochemistry · 2025

Background: Antioxidants are molecules capable of donating one or more electrons to free radicals, thereby stabilizing and neutralizing them. By doing so, antioxidants help protect the body from oxidative stress and its associated health risks. Aims: This study aims to determine...

Open access Research Article 10.9734/ajrb/2025/v15i4411

Agro-morphological Evaluation of Dolichos Bean Genotypes for Promising Line Identification in Tripura, India

Debasmita Sil, Sayan Saha, Tridip Bhattacharjee, Soumitra Sankar Das, Kunal Debbarma, Tapan Kumar Maity & Debashish Sen · Asian Journal of Research in Biochemistry · 2025

Background: To characterize Dolichos bean germplasm collected from different sources based on agro-morphological characteristics and identify suitable Bean lines used as Vegetable purpose in the hilly region of Tripura, field experiment was carried out at the Experimental Farm of...

Open access Research Article 10.9734/ajrb/2025/v15i4410

Evaluation of Physicochemical Parameters Influencing Bioavailability and Therapeutic Potential in Nucleoside Analogues

Madhukant Vashishtha & Danveer Singh Yadav · Asian Journal of Research in Biochemistry · 2025

This research systematically investigates the physicochemical properties of novel nucleoside analogues, highlighting their molecular weight, lipophilicity (LogP), solubility, topological polar surface area (TPSA), drug-likeness, bioavailability, and hydrogen bonding characteristi...

Open access Research Article 10.9734/ajrb/2025/v15i4409

The Potential Role of Selenoproteins in Modulating Malaria Parasite Resistance to Artemisinin-based Combination Therapies (ACTs) in Africa

Uchechukwu Richard Njoku & Chukwuma Raphael Ekeanyanwu · Asian Journal of Research in Biochemistry · 2025

This review synthesises current knowledge on the structure, function, and expression of Plasmodium falciparum selenoproteins, focusing on thioredoxin reductase (PfTrxR), and their role in mitigating artemisinin-induced oxidative damage. Resistance to artemisinin-based combination...

Open access Research Article 10.9734/ajrb/2025/v15i4408

Evaluating the Antioxidant Activity and Identifying Potent Compounds Using GC-MS Analysis of Allium cepa (Onion), Allium sativum (Garlic) and Zingiber officinale (Ginger) Methanol Extracts

Adindu Oluomachi, Umaru Hauwa Aduwamai & Sambo Ponfa · Asian Journal of Research in Biochemistry · 2025

Background: Candidiasis caused by Candida albican species is one of the major health problems in immune-compromised patients in developing countries. Candida species are involved in the main opportunistic yeast infection in the world, but among the species of the genus, Candida a...

Open access Research Article 10.9734/ajrb/2025/v15i4406

Comprehensive Ethnomedicinal and Phytopharmacological Review of Jatropha tanjorensis

Ikalo David Oseghale, Godwin Mmaduabuchi Ikokwu, Osedebamen Hilary Ralph-Okhiria, Praise ODUNVBUN & Adeola Munirah ADEDOTUN · Asian Journal of Research in Biochemistry · 2025

Background: Jatropha tanjorensis is a medicinal shrub widely used in Nigerian traditional medicine. It contains bioactive compounds like polyphenols, saponins, and alkaloids, which are responsible for its antioxidant, anti-inflammatory, antidiabetic, and hepatoprotective effects....

Open access Research Article 10.9734/ajrb/2025/v15i4407

Effect of Indole-3-butyric Acid, Aspirin and Natural Plant Extracts on Rooting of Chrysanthemum (Dendranthema grandiflora L.) cv. Flirt

Tosali Trishna Sahoo, Kaberi Maharana, Sashikala Beura & Sweta Subhashree Jena · Asian Journal of Research in Biochemistry · 2025

Study entitled “Effect of Indole-3-butyric acid, Aspirin and Natural Plant Extracts on Rooting of Chrysanthemum (Dendranthema grandiflora L.) cv. Flirt” was carried out in form of pro-tray experiment under polyhouse of the Department of Floriculture and Landscaping of College of...

Open access Research Article 10.9734/ajrb/2025/v15i4405

Detection of Male Infidelity through Biochemical Analysis of Seminal Related Enzymes Prostate Specific Antigen and Acid Phosphatase

Augustina Usman Ileimokumo, Solomon Eni-yimini Agoro & Gbeinbo F. Livingstone · Asian Journal of Research in Biochemistry · 2025

Background: This study investigated the use of seminal-related enzymes, Prostate Specific Antigen (PSA) and Acid Phosphatase (AP), for detecting semen on male underwear as a potential method for identifying male infidelity. Objective: The primary aim was to assess the effectivene...

Open access Research Article 10.9734/ajrb/2025/v15i4404

Fasting and Post-Prandial Effect of Moringa Stem Extract on Glucose and Fasting Lipids on Healthy Residents of Rivers State

Arit Okechukwu Nwogu, Anyalebechi Eberechukwu Okwuchi & Ibioku Elekima · Asian Journal of Research in Biochemistry · 2025

Moringa plant is an ancient medicinal plant that is widely researched using its leaves, but limited work is done on the stem. Empirical studies using albino rats reveal how good Moringa leaves are in combating hyperlipidemia and hyperglycemia. The study was done to evaluate the e...

Open access Research Article 10.9734/ajrb/2025/v15i4403

Physical Quality of Raw Milk Marketed in and Around Guwahati City, Assam, India

Smita Kakati, A Talukdar & R A Hazarika · Asian Journal of Research in Biochemistry · 2025

Introduction: Milk, a nutritionally complete food, is susceptible to contamination throughout the supply chain—from production to consumption. Ensuring its physical quality is crucial for safeguarding public health. Problem: In India, particularly in urban and peri-urban regions...

Open access Research Article 10.9734/ajrb/2025/v15i4402

Exploring the Neuroprotective Effects of Some New Quinoxalines: A Novel Approach to Alzheimer's Disease Management

Praphulla Kumar Singh & Babu Nand Choudhary · Asian Journal of Research in Biochemistry · 2025

Alzheimer's disease (AD) is a disabling neurodegenerative disorder characterized by irreversible cognitive decline, extracellular deposition of β-amyloid plaques, hyperphosphorylation of tau protein, oxidative stress, and neuroinflammation. Symptoms are all that present-day drugs...

Open access Research Article 10.9734/ajrb/2025/v15i3400

Heavy Metal Exposure in Peri-Mineral Areas of The Bandama River Zone: The Case of The Village of Zagouta in Bouafle Department

Angbo Kousso Marie Angéline, Kambou Sansan Phillippe, Gauze Chantal, Massara Camara Cissé, Djohan Ferdinand & Agnissan Daniel N’guessan · Asian Journal of Research in Biochemistry · 2025

Background and Objective: Humans are exposed to metals through their diet and lifestyle, such as in gold panning. Some metals are essential to the physiological functions of the body, while others are non-essential and can be toxic to humans. The aim of this study is therefore to...

Open access Research Article 10.9734/ajrb/2025/v15i3399