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All published articles 195

Prevalence, Antibiotic Resistance Patterns and Plasmid Mediated Resistance of Extended-spectrum Beta-lactamase Producing Escherichia coli Isolated from Long-term Hospitalized Patients

Nkemdilim Clairelouise Okechukwu, Theophilus Kachi Udeani, Uzoma Chukwunonso Okechukwu, Ifeoma Esther Ani & Emmanuel Ogbonnia Ogudu · Asian Journal of Immunology · 2026

Antimicrobial resistance among healthcare-associated pathogens remains a major challenge, particularly among long-term hospitalised patients who are frequently exposed to antimicrobial therapy and healthcare environments. This study investigated the prevalence, antibiotic resista...

Open access Research Article 10.9734/aji/2026/v9i1201

One Health for Cancer Prevention: Integrating Human, Animal and Environmental Evidence into a Global Transdisciplinary Policy Framework

Christopher Ononiwu Elemuwa · Asian Journal of Immunology · 2026

Cancer prevention is usually organised within human health systems, although important carcinogenic processes arise from shared biological, environmental, food-system and occupational exposures that cross species and administrative boundaries. This critical narrative review evalu...

Open access Research Article 10.9734/aji/2026/v9i1200

Exploratory Assessment of Leukocyte Adherence Inhibition Test and Tube Precipitation Responses to Evaluate Cross-reactivity between Latex and Pollen Allergens in Patients with Allergic Multimorbidity

Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Cibele Silva Miguel, Nicole Sartoreto Rocha, Alessandra Vieira de Oliveira, Luciana Sacilotto Carvalho, Raquel Acácia Pereira Gonçalves Santos, Jhéssica Letícia Santos Santana & Regiane Patussi Santos Lima · Asian Journal of Immunology · 2026

Background: Clinical hypersensitivity to pollen and latex allergens has been studied and linked to hypersensitivity to a variety of fruits and vegetables, making this a complex field of study for respiratory, occupational, and food-allergic patients. Aim: To evaluate the potentia...

Open access Research Article 10.9734/aji/2026/v9i1199

Socio-Demographic Determinants of Complete Childhood Immunization Coverage among Caregivers in Rural Nasarawa State, Nigeria

S. K. Bello, A. Nyamve, I. H. Nkene, S. C. Hassan, R. P. Galleh & S. C. Tama · Asian Journal of Immunology · 2026

Aims: This study examined the socio-demographic determinants of complete childhood immunisation coverage among caregivers in rural communities of Nasarawa State, Nigeria, over the period 2016–2025, with attention to trends, prevalence, associated caregiver-level determinants, and...

Open access Research Article 10.9734/aji/2026/v9i1198

Impact of Stress and Obesity on Cancer

Byiringiro Christophe, Theresia Indah Budhy & Viskasari Pintoko Kalanjati · Asian Journal of Immunology · 2026

Cancer development and progression are influenced by interacting biological, metabolic, immune, and psychosocial factors. Chronic psychological stress and obesity are potentially modifiable conditions that may contribute to a tumour-promoting environment through neuroendocrine ac...

Open access Research Article 10.9734/aji/2026/v9i1197

Oncogenic Viruses and Human Cancer: Molecular Mechanisms, Diagnostics, Vaccines and Therapeutic Advances

Christopher Ononiwu Elemuwa · Asian Journal of Immunology · 2026

Oncogenic viruses are preventable or therapeutically tractable causes of a substantial and geographically unequal fraction of human cancer. Their biological diversity, from small DNA viruses to retroviruses and non-integrating RNA viruses, has produced distinct tumour phenotypes...

Open access Research Article 10.9734/aji/2026/v9i1196

Exploratory Assessment of Leukocyte Adherence Inhibition Test and Tube Precipitation Responses to Hexavalent and Trivalent Chromium in Patients with Suspected Allergic Contact Dermatitis

Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Cibele Silva Miguel, Alessandra Vieira de Oliveira, Luciana Sacilotto Carvalho, Nicole Sartoreto Rocha & Raquel Acácia Pereira Gonçalves Santos · Asian Journal of Immunology · 2026

Background: Chromium compounds can elicit hypersensitivity reactions. No standardised laboratory assay is available to quantify the relative contributions of humoral and cellular mechanisms within an individual patient’s phenotype, apart from in vivo provocation testing. Aim: To...

Open access Research Article 10.9734/aji/2026/v9i1194

A Critical Review on Mechanistic Cross Talk between Paediatric Inflammation and GH-IGF-1 Axis in Childhood Growth

T. Ashraf, Fawzia Alyafei, Nada Alaaraj, Noor Hamed & Shayma Ahmed · Asian Journal of Immunology · 2026

Linear growth during childhood is governed by the coordinated action of the growth hormone–insulin-like growth factor-1 (GH–IGF-1) axis, yet this endocrine system does not operate in isolation from the immune system. Chronic and acute inflammatory states, whether triggered by aut...

Open access Research Article 10.9734/aji/2026/v9i1193

Factors that Influenced Acceptance of Covid-19 Vaccination in Afara, Mbaitoli Local Government Area, Imo State

Elekeh Rosemary Ichita, Justice Ngozi & Watson Ogbene Ubi Oke · Asian Journal of Immunology · 2026

Background: COVID-19 vaccination remains one of the most effective strategies for preventing severe illness and controlling the spread of the disease. However, vaccine hesitancy continues to undermine vaccination efforts in many communities, particularly in rural and semi-urban a...

Open access Research Article 10.9734/aji/2026/v9i1192

Immune-Related Adverse Events of Checkpoint Inhibitors: Clinical Spectrum and Insights Across Major Malignancies

A. Mohammed Shefeeq · Asian Journal of Immunology · 2026

Immune checkpoint inhibitors have transformed the management of solid and haematological malignancies by restoring antitumour T-cell activity through blockade of cytotoxic T-lymphocyte-associated protein 4, programmed cell death protein 1, and programmed death-ligand 1. The same...

Open access Research Article 10.9734/aji/2026/v9i1191

Prevalence of Rheumatoid Arthritis, Hepatitis B, and Hepatitis C among Elderly Subjects Attending a Pilgrimage Centre in Elele, Nigeria

B. O. Eledo, K. C. Akanno & V. N. Ben-Eledo · Asian Journal of Immunology · 2026

Rheumatoid Arthritis (RA) is a chronic autoimmune disorder primarily affecting the joints, leading to pain, swelling, stiffness, and eventual loss of function. Hepatitis B and C are liver infections caused by the hepatitis B virus (HBV) and hepatitis C virus (HCV) that can lead t...

Open access Research Article 10.9734/aji/2026/v9i1190

Determinants of Complete Childhood Immunization in Rural Communities of Rivers State, Nigeria: A Randomized Controlled Study

Nduye Christie Tobin Briggs · Asian Journal of Immunology · 2026

Background: Incomplete childhood immunization remains a major public health challenge in rural Nigeria, driven by both caregiver- and health system-related factors. This study assessed the determinants of complete childhood immunization using a community volunteer-driven interven...

Open access Research Article 10.9734/aji/2026/v9i1189

Evaluation of Serum IFN-gamma and IL-10 Equilibrium in HIV-Positive Subjects on ART in Rivers State, Nigeria

Priya Homa Chukwu, Richard Ikechukwu Eze & Anslem Onochie Ajugwo · Asian Journal of Immunology · 2026

Background: In the clinical management of HIV, viral suppression is often the primary focus, yet the underlying immune architecture frequently remains in a state of disharmony. This study investigated the pro-inflammatory (IFN-gamma) and anti-inflammatory (IL-10) profiles of HIV-...

Open access Research Article 10.9734/aji/2026/v9i1188

Immunoinformatics-based Multi-epitope Vaccine Design against Cryptococcus Neoformans Causing Cryptococcal Meningitis

M. Inchal Kaverappa, Suraj Manjunath Goudar, Bhoomika Prasanna Hiremath, L. A. Ramachandra Prasad, V. G. Shanmuga Priya & Chemmugil · Asian Journal of Immunology · 2026

Aims: To develop a multi-epitope vaccine against Cryptococcus neoformans using computational immunoinformatics approaches for the prevention of cryptococcal meningitis. Study Design:  Computational in silico vaccine design study. Place and Duration of Study: The study was perform...

Open access Research Article 10.9734/aji/2026/v9i1187