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All published articles 195

Role of Inflammatory Cytokines in the Pathogenesis of Rheumatoid Arthritis and Novel Therapeutic Targets

Shaayau Shehu, Abdulaziz Umar Kurya, Usama Aliyu & Dinesh C. Sharma · Asian Journal of Immunology · 2020

Cytokines are low molecular weight secreted proteins that mediate and regulate immune responses, inflammation and hematopoiesis; they act by autocrine, paracrine, endocrine and antagonistic mode of actions. cytokines have strong correlation with autoimmune disease, the most promi...

Open access Research Article

Knowledge, Attitude and Uptake of Hepatitis B Vaccine among Clinical Medical Students of a Tertiary Institution in Southeast Nigeria

N. C. Eze, E. C. Egba, J. E. Ogbanna, S. N. Nwamini, P. U. Nweke & J. S. Amasianya · Asian Journal of Immunology · 2020

Background: Hepatitis B virus infection is a global public health problem especially in developing countries like Nigeria. Good knowledge of Hepatitis B virus, its infection and positive attitude by the public are key to the prevention of Hepatitis B infection The infection can b...

Open access Research Article

Acute Immune Mediated Lung Injury in COVID 19: A Review

A. S. V. Prasad · Asian Journal of Immunology · 2020

There are many gaps in our present understanding of the of the SARS CoV 2 related matters like its PAMPs,(pathogen associated molecular patterns),antigenic profile, immune evasive mechanisms and also other host related matters, like PRR s(pattern recognizing receptors) and the de...

Open access Research Article

Molecular Pathogenesis, Clinical Efficacy and Safety of Therapeutics Used in the Treatment of Osteoarthritis

Shaayau Shehu, Abdulaziz Umar Kurya, Kamal Murtala Farouq & Abdulhakim Umar Toro · Asian Journal of Immunology · 2020

Osteoarthritis (OA) also known as degenerative joint disease, is the most common form of arthritis which affects all the tissues of the joint, including the cartilage, bone, ligaments, and muscles. It can develop in any number of joints, but most commonly affects the knees, hands...

Open access Research Article

TNF-α, TNF Receptors and Their Complex Implications in Therapy

Brian Mark Churchill, Pallavi Patri, Rashna Cama & Jula K. Inrig · Asian Journal of Immunology · 2020

Tumor necrosis factor alpha (TNF-α), also called cachectin or cachexin, is a naturally occurring cytokine produced by activated macrophages and monocytes, and to a smaller scale by T-lymphocytes, B-lymphocytes, fibroblasts and astrocytes. It has both inflammatory and immunomodula...

Open access Research Article

Seroprevalence of Rubella IgG and IgM Antibodies among Pregnant Women Attending Antenatal Clinic in Federal Teaching Hospital Ido-Ekiti, Nigeria

Richard Yomi Akele, Baget Nerat Pam, Bernard Oluwapelumi Oluboyo, Seyi Samson Enitan, Janet Funmilayo Akinseye & Funmilayo Ajoke Adewumi · Asian Journal of Immunology · 2020

Aim: Though Rubella is vaccine-preventable and enlisted on the expanded program on immunization (EPI) list, vaccination and testing are not routinely practiced in Ido-Ekiti. There is also paucity of epidemiological data on the prevalence of rubella infection at Ido-Ekiti, hence t...

Open access Research Article

Investigation of Neuropharmacological Effects of Flemingia stricta (Roxb.) Leaves

Md. Shahrear Biozid, Mohammad Nazmul Alam, Md. Jainul Abeden, Md. Masudur Rahman & Md. Rafikul Islam · Asian Journal of Immunology · 2020

Background: Traditional preparation of the leaf of Flemingia stricta (Fabaceae) Roxb. , a medicinal plant of the Indian subcontinent, has been used for the treatment of different diseases as a herbal preparation. Our purpose was to analyze the neuropharmacological effects of diff...

Open access Research Article

Stem Cell Therapy in Treatment of Non-communicable Diseases: Possibilities and Challenges

Nahian Rahman, Mussamat Mahbuba Sultana, Marium Sultana, Susmita Ghosh, Urme Mostary, Priya Saha & Md. Ruhul Kabir · Asian Journal of Immunology · 2020

Over recent years stem cells have stood out as a promising tool for regenerative medicine, providing alternative therapeutic solutions for many non-communicable diseases. Many clinical trials using stem cells or induced pluripotent stem cells are focused on the refit and regenera...

Open access Research Article

Polyphenol and Flavonoids Content and Antioxidant Activity of Different Solvent Extracts from Artemisia argyi

Dong-Qin Wang, Jing Yang & Jianguo Xu · Asian Journal of Immunology · 2020

The effects of extraction solvents (methanol, ethanol, acetone, petroleum ether and n-hexane) on the content of total polyphenols and flavonoids, as well as antioxidant activities of Artemisia argyi were investigated. The results showed that, the ethanol extract had the highest t...

Open access Research Article

Structure and Function of COVID-19 Encode Proteins in the Transcription and Replication Mechanism with Its Preventive Measures and Propose Efficacy Treatments: A Critical Systematic Review

Oguh C. E., Obiwulu E. N. O., Oniwon W. O., Okekeaji U., Ugwu C. V., Umezinwa O. J. & Osuji C. A. · Asian Journal of Immunology · 2020

The sudden occurrence outbreak of coronavirus disease in 2019 (COVID-19) by the severe acute respiratory syndrome coronavirus2 (SARS-CoV-2) poses a serious harm worldwide and local economies. Due to high numbers of infection and death, the pandemic calls for an urgent demand of a...

Open access Research Article

Preliminary Report on the Prevalence of Intestinal Parasites and Malaria among People Living with HIV/AIDS within Makurdi Metropolis, Benue State, Nigeria

O. T. Makwe, V. U. Obisike, O. Amali & G. N. Imandeh · Asian Journal of Immunology · 2020

This research was conducted to determine the prevalence of intestinal parasites and malaria among people living with HIV/AIDS within Makurdi metropolis, Benue State, Nigeria. Four hundred (400) blood and stool samples of people living with HIV/AIDS were collected from 45 NAF Base...

Open access Research Article

Neutrophils’ Phagocytic Function of Hepatitis B Virus Infected Pregnant Women, Attending Specialist Hospital Sokoto, North Western, Nigeria

C. O. Onwuliri, C. C. Onyenekwe, M. H. Yeldu, A. A. Panti, A. B. Shuaibu & M. Kalgo · Asian Journal of Immunology · 2020

Hepatitis B virus is the causative agent of hepatitis B infection. The virus is a major public health crisis in sub-Saharan Africa with high burden of morbidity and mortality. Vertical transmission is a significant contributor of new cases. This study was designed to access the i...

Open access Research Article