Background: Incomplete childhood immunization remains a major public health challenge in rural Nigeria, driven by both caregiver- and health system-related factors. This study assessed the determinants of complete childhood immunization using a community volunteer-driven interven...
Open access
Research Article10.9734/aji/2026/v9i1189
Background: In the clinical management of HIV, viral suppression is often the primary focus, yet the underlying immune architecture frequently remains in a state of disharmony. This study investigated the pro-inflammatory (IFN-gamma) and anti-inflammatory (IL-10) profiles of HIV-...
Open access
Research Article10.9734/aji/2026/v9i1188
M. Inchal Kaverappa, Suraj Manjunath Goudar, Bhoomika Prasanna Hiremath, L. A. Ramachandra Prasad, V. G. Shanmuga Priya & Chemmugil·Asian Journal of Immunology·2026
Aims: To develop a multi-epitope vaccine against Cryptococcus neoformans using computational immunoinformatics approaches for the prevention of cryptococcal meningitis. Study Design: Computational in silico vaccine design study. Place and Duration of Study: The study was perform...
Open access
Research Article10.9734/aji/2026/v9i1187
Background: Malaria in pregnancy is associated with adverse maternal and fetal outcomes, partly driven by immune dysregulation and altered cytokine responses. Pro-inflammatory and anti-inflammatory cytokines influence disease severity, yet their precise profiles in malaria-infect...
Open access
Research Article10.9734/aji/2026/v9i1186
R. Nitish Kumar, Parvana Nair, Kesiya Joy, L. A. Ramachandra Prasad & V. G. Shanmuga Priya·Asian Journal of Immunology·2026
Background: Norovirus, a non-enveloped, positive-sense single-stranded RNA virus belonging to the Caliciviridae family, is a leading cause of acute gastroenteritis (AGE) globally, accounting for approximately 19–21 million cases annually in the United States alone. The rapid emer...
Open access
Research Article10.9734/aji/2026/v9i1184
Shelly Chinwe Ogbu, Moses Zira Zaruwa, Mairiga Jamey Peters, Arikpo Kebe Etim, Chi-kadibia Theophilus Ukoma, Benson Obiageli, Ernest Ikechukwu Ogbu & Christiana Bala Joseph·Asian Journal of Immunology·2026
Pharmacological exploitation of natural compounds has lead to the development of non-synthetic and non-toxic agents that are promising at ameliorating the menace of neoplastic diseases such as leukemia. The aim of this study was to determine the phytochemical and anti-leukemic ef...
Open access
Research Article10.9734/aji/2026/v9i1185
Staphylococcus aureus is a prevalent pathogen in both hospital and community settings and is frequently implicated in wound infections. In light of its clinical significance, the research was carried out to determine the prevalence of mec-A positive Staphylococcus aureus and PVL...
Open access
Research Article10.9734/aji/2026/v9i1183
Background: In early childhood, type 1 diabetes mellitus (T1DM) is an autoimmune illness marked by the death of pancreatic β-cells by the immune system. Autoantibodies that are important indicators of illness etiology and diagnosis include insulin autoantibodies (IAA), glutamic a...
Open access
Research Article10.9734/aji/2026/v9i1182
Background: Rotavirus is a leading cause of severe diarrhea among children under five years of age globally, with Nigeria bearing a significant burden. Despite the introduction of the rotavirus vaccine into Nigeria’s national immunisation schedule, uptake remains suboptimal in ma...
Open access
Research Article10.9734/aji/2026/v9i1181
Routine childhood immunization remains one of the most cost-effective public health interventions, yet Nigeria continues to experience substantial gaps in coverage, timeliness, and completion of recommended vaccine series. These gaps are not uniform: they cluster by geography, so...
Open access
Research Article10.9734/aji/2026/v9i1180
Background: Edible chalk (Nzu), a geophagic kaolin widely consumed in several African communities, particularly among women, has been associated with both perceived health benefits and potential toxicological risks. This study investigated the immunomodulatory effects of edible c...
Open access
Research Article10.9734/aji/2026/v9i1179
Tuberculosis (TB) is the second most deadly airborne infectious disease caused by Mycobacterium tuberculosis, posing a major global health risk dw. Nearly one-third of the world’s population is infected, with low-income countries most affected due to limited access to diagn...
Open access
Research Article10.9734/aji/2025/v8i1178
Islam Ariremako Jimoh, TOBECHI BRENDAN NNANNA, TAIWO MICHEAL OLUMUJI, Paul Onyekachi Ukegbu, Michael Sewanu Hungbo & Kanime Hussaini·Asian Journal of Immunology·2025
Background: Immune checkpoint blockade (ICB) has transformed oncology, but its efficacy is limited by primary and acquired resistance. The gut microbiome is a established determinant of ICB response, while neutrophil extracellular traps (NETs) have recently emerged as key mediato...
Open access
Research Article10.9734/aji/2025/v8i1177
Background: Tumour necrosis factor alpha (TNF-α) and Adiponectin are both Pro and anti-inflammatory cytokines that play major roles in the pathogenesis and therapeutic management of many metabolic diseases. Aim: This study aimed at evaluating the role of TNF-α and Adiponectin amo...
Open access
Research Article10.9734/aji/2025/v8i1176
Hayder Abdul Hussein Abass, Zainab Abdul Kareem Ataia, Ihsan K. A. Alkardhi & Hayder Ali Muhammed·Asian Journal of Immunology·2025
Oral candidiasis, caused predominantly by Candida albicans, represents one of the most common opportunistic fungal infections in pediatric populations. This study investigates the immunological responses and molecular characterisation of Candida colonisation in the oral cavities...
Open access
Research Article10.9734/aji/2025/v8i1175