Background: Human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) remain major health problems worldwide, with high mortality and morbidity rates, particularly in developing countries. The United Nations Programme on HIV/AIDS (UNAIDS) reported that ther...
Open access
Research Article10.9734/aji/2025/v8i1159
Background: Cocoa is one of the foods more consistently associated with high nickel content, a metal that functions as a hapten responsible for various non–IgE-mediated symptomatic hypersensitivities. Aim: The present study is a proof-of-concept that hypothesizes that LAIT and th...
Open access
Research Article10.9734/aji/2025/v8i1158
There is a mutual bidirectional cross-talk between mammalian microbiomes MM and their respective immune systems during the host homeostatic and disease states, the microbiome- immune axis. The objective of the present opinion paper was to map the current status of the microbiome-...
Open access
Research Article10.9734/aji/2025/v8i1157
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Cibele Silva Miguel, Raquel Acácia Pereira Gonçalves Santos, Nicole Sartoreto da Rocha, Jhéssica Letícia Santos Santana & Regiane Patussi Santos Lima·Asian Journal of Immunology·2025
Background: Allergies to citrus fruits are often associated with pollinosis due to cross-reactivity among pollen and food allergens (fruit-pollen syndrome) displayed in patients with several conditions, such as allergic rhinoconjunctivitis. Aim: To evaluate the potential of the T...
Open access
Research Article10.9734/aji/2025/v8i1156
The preclinical immunogenicity of capsule C and outer membrane protein OMP of human neurotropic isolate of Hemophilus influenzae b HIB in a lapin model is being reported. Hemophilus influenzae b is gram negative, short rods, encapsulated bacterium, microaerophilic, fastidious, ne...
Open access
Research Article10.9734/aji/2025/v8i1155
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Cibele Silva Miguel, Raquel Acácia Pereira Gonçalves Santos, Jhéssica Letícia Santos Santana & Regiane Patussi Santos Lima·Asian Journal of Immunology·2024
Background: Several publications report lanolin as responsible for hypersensitivity reactions in patients with atopic dermatitis and/or contact dermatitis, as diagnosed by in vivo provocation tests. There is no standardized lab exam that can endotype the mechanisms responsible fo...
Open access
Research Article10.9734/aji/2024/v7i1154
Nikita Gupta, Mohd Naveed Khan, Varda Farooqui, Guntoju Poojitha & Thipparam Kavya·Asian Journal of Immunology·2024
Vadadustat, a hypoxia-inducible factor prolyl hydroxylase inhibitor, may offer an oral alternative to injectable erythropoiesis-stimulating agents (ESAs) to treat anemia in patients undergoing peritoneal dialysis. Current standard of care for anemia linked to chronic kidney disea...
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Research Article10.9734/aji/2024/v7i1153
Onaolapo, Y.A., Mazadu, R.M., Baraya, K.Y., Fasuyi, F.H., Irhue, A.E., Ahmed, B., Hassan, A., Shehu, A.A., Bala, S.B., Kasim, S.N. & Kugama, M.A.·Asian Journal of Immunology·2024
Animal African trypanosomiasis is a protozoan disease caused by trypanosomes and transmitted through the bite of an infected tsetse fly. The disease has an adverse effect to the economy of the affected areas and drugs used for the treatment of the disease are faced with several c...
Open access
Research Article10.9734/aji/2024/v7i1152
pneumoniae is one of the principle human pneumopathogen. Such pathogenicity features in man can be delineated by severity, capsule nature and yield of pure growth onto primary plate cultures. While in laboratory animal models, it accounts for; the nature of capsule serotype, shor...
Open access
Research Article10.9734/aji/2024/v7i1151
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Cibele Silva Miguel, Raquel Acácia Pereira Gonçalves Santos, Jhéssica Letícia Santos Santana & Regiane Patussi Santos Lima·Asian Journal of Immunology·2024
Background: Hypersensitivity to chicken eggs is the second most common food allergy, presenting IgE-mediated and non-IgE-mediated hypersensitivity mechanisms. While IgE-mediated hypersensitivity is easily detected, non-IgE-mediated endotypes present challenging obstacles to diagn...
Open access
Research Article10.9734/aji/2024/v7i1150
Mfon I Akpaso, Elton N Takim, Michael E Oku, Anani, S.E., Lydia B Edim & Gabriel U Udo-Affah·Asian Journal of Immunology·2024
Diabetes mellitus is a disorder in which the body fails to produce enough or respond normally to insulin, leading to abnormally high blood sugar levels. The study was aimed at investigating the effects of ethanolic extract of Curcuma longa (Tumeric) on fertility profile and gonad...
Open access
Research Article10.9734/aji/2024/v7i1149
Chemoimmunotherapy was a challenge issue in an early clinical study. Cytotoxic chemotherapy was immunosuppressive while, in the clinic, chemoimmunotherapy demonstrated supporting immunotherapy. To increase ACT (adoptive cell transfer) immunotherapy and decrease the effects of che...
Open access
Research Article10.9734/aji/2024/v7i1148
The ongoing COVID-19 pandemic underscores the urgent need for effective vaccination strategies to mitigate disease burden. The development of neutralizing antibodies is a critical indicator of host defence mechanisms against life-threatening infectious diseases, such as those cau...
Open access
Research Article10.9734/aji/2024/v7i1147
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Cibele Silva Miguel, Raquel Acácia Pereira Gonçalves Santos, Jhéssica Letícia Santos Santana & Regiane Patussi Santos Lima·Asian Journal of Immunology·2024
Background: Several publications report that tartrazine is responsible for IgE-mediated and non–IgE-mediated hypersensitivity reactions. There is no standardized lab exam to endotype non–IgE-mediated immunoreactivity against tartrazine besides in vivo provocation tests. Aim: To e...
Open access
Research Article10.9734/aji/2024/v7i1146
Introduction: Viral hepatitis which includes five the main strains of hepatotropic viruses, hepatitis A (HAV), hepatitis B (HBV), (HBA), hepatitis C (HCV), hepatitis D(HDV), and hepatitis E (HEV), are leading causes of morbidity and mortality globally. Much public health attentio...
Open access
Research Article10.9734/aji/2024/v7i1145