There were shared allergenicity in delayed type hypersensitivity between the protoplasmic sonicate proteins of Pseudomonas aeruginosa with that of Klebsiella oxytoca Mild erythema was noted from 6 to72 hrs post to P. aeruginosa (PSP) in Klebsiella oxytoca PSP primed rabbits (KOPS...
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Research Article10.9734/aji/2024/v7i1142
Yassir Lakrafi, Benhayoun Basma, Cherfouf Rihabe, Bouroyene El Mehdi, Barakat Leila, Benzakour Merieme, Khadija Echchilali, Mina Moudatir & Hassan El Kabli·Asian Journal of Immunology·2024
Systemic sclerosis is a non-organ-specific autoimmune disease of the connective tissue, characterized by excessive production of collagen leading to fibrosis of the skin as well as organs such as the lung, it is responsible for aesthetic discomfort, an alteration of the functiona...
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Research Article10.9734/aji/2024/v7i1140
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Jhéssica Letícia Santos Santana, Raquel Acácia Pereira Gonçalves Santos & Regiane Patussi Santos Lima·Asian Journal of Immunology·2024
Background: Several publications report that aluminum is responsible for hypersensitivity reactions. There is no standardized lab exam that can endotype (determine the pathophysiology responsible for the phenotype) hypersensitivity to aluminum. Aim: To evaluate the potential of t...
Open access
Research Article10.9734/aji/2024/v7i1139
Background: Diabetes mellitus is a chronic metabolic dysfunction marked with prolonged excessive glucose level, with disruptions in the metabolism of starch, lipids, and amino acids due to excessive production and/or inadequate utilization of glucose. Objective: To assess the pr...
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Research Article10.9734/aji/2024/v7i1138
Rheumatoid arthritis (RA) is characterized by systemic synovitis, which destroys joints. With the discovery of biological disease-modifying anti-rheumatic medicines (bDMARDs) and the combination of traditional DMARDs, clinical remission is now seen as a reasonable and achievable...
Open access
Research Article10.9734/aji/2024/v7i1137
Over the period 01/01/2013 until 31/08/2023, 13 907 total plasma IgE determinations were performed in the analytical laboratory of the Provincial Hospital in Opole. Among these determinations, there were 377 results below 2.0 U/l (in 279 patients), with the ultra-extremely low re...
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Research Article10.9734/aji/2024/v7i1136
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Jhéssica Letícia Santos Santana, Raquel Acácia Pereira Gonçalves Santos & Regiane Patussi Santos Lima·Asian Journal of Immunology·2024
Background: Several publications report polyethylene glycols (PEGs) and PEGylated therapeutics as responsible for non–IgE-mediated allergic reactions. There is no standardized lab exam that can endotype (quantify the participation of these mechanisms inside each patient’s pattern...
Open access
Research Article10.9734/aji/2024/v7i1135
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Jhéssica Letícia Santos Santana, Raquel Acácia Pereira Gonçalves Santos, Regiane Patussi Santos Lima & Everton Salgado Monteiro·Asian Journal of Immunology·2024
Background: Several publications report Dermatophagoides farinae allergens as responsible for several types of non–IgE-mediated allergic reactions. There is no standardized lab exam to endotype (quantify the participation of these mechanisms) in the context of allergic disease pa...
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Research Article10.9734/aji/2024/v7i1134
Nikita Gupta, Sana Begum, Varda Farooqui, Summaiya Afreen & Pranitha Avunoori·Asian Journal of Immunology·2024
Iguratimod is a small novel compound considered as a disease-modifying anti-rheumatic drug (DMARD), which exhibits anti-inflammatory and immunomodulatory effects. Iguratimod acts directly on B cells by inhibiting the production of inflammatory cytokines (tumor necrosis factor-α,...
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Research Article10.9734/aji/2024/v7i1132
Immunological assays are fundamental tools in modern diagnostics, providing indispensable insights vital for clinical decisions and scientific inquiries. However, the reliability of these assays is at times compromised by various interferences, casting doubt on the authenticity o...
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Research Article10.9734/aji/2024/v7i1131
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Jhéssica Letícia Santos Santana, Raquel Acácia Pereira Gonçalves Santos & Regiane Patussi Santos Lima·Asian Journal of Immunology·2024
Background: Several publications report benzoic acid as responsible for non–IgE-mediated allergic reactions. No standardized lab exam identifies these reactions besides in vivo provocation tests. Aim: To evaluate the potential of the Leukocyte Adherence Inhibition Test (LAIT) to...
Open access
Research Article10.9734/aji/2024/v7i1130
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Jhéssica Letícia Santos Santana, Raquel Acácia Pereira Gonçalves Santos & Regiane Patussi Santos Lima·Asian Journal of Immunology·2024
Aim: To evaluate the potential of the Leukocyte Adherence Inhibition Test (LAIT) to evaluate immunoreactivity against peanut proteins in patients with a clinical diagnosis of non–IgE-mediated Atopic Dermatitis (AD). Study Design: We retrospectively examined the medical charts of...
Open access
Research Article10.9734/aji/2024/v7i1129
Background and aims: DTT treatment and heat inactivation are the two common methods used for removing the interference of IgM antibodies which can affect the accuracy of IgG measurements. By comparing the effects of these treatments on ABO isoagglutinin titers using two different...
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Research Article10.9734/aji/2024/v7i1128
Introduction: BCG childhood vaccination is still in use all over the world.BCG within the continuum of vaccinee childs activate immune cells to produceTH1 and TH2 cytokines The present work was aimed at investigating IL2 and IL4 cytokine responses among BCG pediatric vaccinee and...
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Research Article10.9734/aji/2024/v7i1127
Oketah E. N., Frank-Peterside N., Elechi C. R., Ugwu C. H., Onu E. N., Okonko B. J., Igwe M. U., Cookey T. I., Adim C. C., Innocent-Adiele H. C., Okerentugba P. O. & Okonko I. O.·Asian Journal of Immunology·2024
Herpes simplex virus has public health importance as a leading cause of genital ulcers, which also facilitate human immunodeficiency virus while co-infection with hepatitis C virus and human immunodeficiency virus is common in certain populations. This study was carried out with...
Open access
Research Article10.9734/aji/2024/v7i1126