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All published articles 475

Influence of Gut Microbes on the Incretin System and Type 2 Diabetes Mellitus: A Critical Narrative Review

S S Sreenvas · Asian Journal of Medical Principles and Clinical Practice · 2026

Type 2 diabetes mellitus remains one of the principal drivers of global non-communicable disease burden, and impaired secretion or action of the incretin hormones glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide is now recognised as a core feature of its p...

Open access Research Article 10.9734/ajmpcp/2026/v9i2462

Nurses Knowledge and Perception on Patient Acuity Tool and Their Relationship with Self-assessed Patient Outcomes in Houston, Texas, United States of America

Raymond. B. Sarmiento & Joseph Michael Manlutac · Asian Journal of Medical Principles and Clinical Practice · 2026

This study assessed registered nurses’ knowledge and perceptions of the Patient Acuity Tool (PAT) and examined their relationship with self-assessed patient outcomes in acute care settings in Houston, Texas, United States. A quantitative descriptive-comparative-correlational desi...

Open access Research Article 10.9734/ajmpcp/2026/v9i2461

Rituximab Infusion-Related Reactions in Routine Clinical Practice: A Retrospective Pharmacovigilance Study from Iraq

Yasser J. H. Alyassery & Riam Diaa · Asian Journal of Medical Principles and Clinical Practice · 2026

Background: Rituximab (RTX) is widely used for autoimmune and haematological diseases, but infusion-related adverse drug reactions (ADRs) remain a clinically important safety concern in routine care. Aim: This retrospective pharmacovigilance study described rituximab-associated a...

Open access Research Article 10.9734/ajmpcp/2026/v9i2460

A Systematic Review on Genetic Polymorphisms Associated with Hypertension Risk

Jaiyeoba-Ojigho Jennifer Efe, Omashim Oluwakemi Ochonogor, Chris-Ozoko Ebele Lilian, Ubogu Joseph Afokeoghene, Okolie Emmanuel Ikechukwu, David Chinaecherem Innocent, Innocent Onyesom, Ovuakporaye Simon Irikefe, Okonkwo Charles Chinemerem, Imariabe Nosakhare Samuel, Etugbo Ann Omamuzo, Jeremiah Ogheneyole, Uti Praise Obielumani, Uririoghene Annabel Duruvwe & Anyanwu Chidinma · Asian Journal of Medical Principles and Clinical Practice · 2026

Background: Hypertension is a major global public health burden with a significant heritable component. Despite extensive genomic research, evidence linking specific genetic polymorphisms to hypertension risk remains inconsistent, partly due to a lack of diversity in study popula...

Open access Research Article 10.9734/ajmpcp/2026/v9i2459

Bridging the Knowledge - practice Gap in Emergency Care at the Primary Healthcare Level: Evidence from Ahafo Ano North Municipality, Ghana

Asafo, T. A. Adjei, Albert Opoku, Henrietta Delecter Ntow, Augustina Barbara Nkrumah, Raymond Ahenkorah & Yvonne Arhin Sarpong · Asian Journal of Medical Principles and Clinical Practice · 2026

Emergency care at the primary healthcare level is essential for the timely assessment, stabilisation, and referral of patients with acute illnesses and injuries, particularly in rural settings where access to higher-level facilities may be delayed. This study examined emergency c...

Open access Research Article 10.9734/ajmpcp/2026/v9i2458

Effects of the Use of Information and Communication Technology on the Quality of Health Services in Public and Private Health Facilities: A Systematic Review

Chukwuma Chibuike Barnabas, Omosivie Maduka, Barilee B. Baridam, Irima Odo, Daniel Okon, Okongko Aniefiok Dickson & Emmanuel Etim Clement · Asian Journal of Medical Principles and Clinical Practice · 2026

Background: Information and Communication Technology is increasingly used in health facilities to support documentation, communication, clinical decision-making, telemedicine, patient engagement, surveillance and health information management. This systematic review examined evid...

Open access Research Article 10.9734/ajmpcp/2026/v9i2457

Therapeutic Effect of Ethanolic Extract of Zingiber officinale (Ginger Rhizomes) on Selected Biochemical Parameters and Some Electrolytes in Male Wistar Rats

Kanayo M. Odia, Akpere Hallo-Rume, Lauritta C. Ndufeiya-Kumasi, Miebaka Beverly Otobo, Victor Eboseyi Ukpebor & Nicholas Asiwe · Asian Journal of Medical Principles and Clinical Practice · 2026

This study evaluated the effect of ethanolic extract of Zingiber officinale (ginger rhizomes) on selected biochemical parameters and electrolytes in male Wistar rats. Twenty healthy adult male Wistar rats weighing about 150 g were randomly assigned to four groups of five rats eac...

Open access Research Article 10.9734/ajmpcp/2026/v9i2456

Clinical Impact of Rifaximin in Liver Cirrhosis: A Critical Review

Shariya Tanaaz, K. Akash, Nabeeha Zufi, Nabila Fathima & E. Vyshnavi · Asian Journal of Medical Principles and Clinical Practice · 2026

Liver cirrhosis represents a major contributor to global morbidity and mortality, characterised by progressive hepatic fibrosis, portal hypertension, and susceptibility to life-threatening complications including hepatic encephalopathy (HE), spontaneous bacterial peritonitis (SBP...

Open access Research Article 10.9734/ajmpcp/2026/v9i2455

Features of Early Osteoarthritis and Synovitis against the Background of Metabolic Syndrome: A Cross-Sectional Study

Nabiyeva Dildora Abdumalikovna, Abdurazzakova Dilrabo Seytbayevna, Matchanov Seytbay Xudoybergenovich, Tashpulatova Maktuba Muhamedali Qizi & Xo’shnayev Mahmud Almardon O’g’li · Asian Journal of Medical Principles and Clinical Practice · 2026

Background: Early knee osteoarthritis may present with pain, stiffness, and functional limitation despite minimal radiographic changes. Metabolic syndrome may contribute to a more symptomatic and inflammatory disease pattern. Objective: This cross-sectional study evaluated the cl...

Open access Research Article 10.9734/ajmpcp/2026/v9i2453

Effectiveness of Strategies to Enhance Patients’ Compliance with Clinical Appointments: A Systematic Review

Oji-Nelson Marvelous Kelechi, Best Ordinioha, Orieke Rebecca Kalu, Irima Odo & Daniel Okon · Asian Journal of Medical Principles and Clinical Practice · 2026

Missed clinical appointments remain an important barrier to continuity of care, timely clinical review, and efficient use of health service resources. This systematic review examined strategies used to improve patients’ compliance with scheduled clinical appointments across globa...

Open access Research Article 10.9734/ajmpcp/2026/v9i2454

The Importance of the Two-way Referral System in Healthcare Delivery: A Survey of Oju Local Government Area, Benue State, Nigeria

Ojenya Freedom Otor & Ochelle Jennifer Okwa · Asian Journal of Medical Principles and Clinical Practice · 2026

The two-way referral system is a bidirectional mechanism that enables patients to move between levels of healthcare according to clinical need and return to the originating provider with relevant feedback for continued management. This study examined the importance of the two-way...

Open access Research Article 10.9734/ajmpcp/2026/v9i2451

Prevalence of Text Neck Syndrome and Its Impact on Workplace Productivity and Activities of Daily Living among the Digital Workforce: A Cross-sectional Study

Soumitro Biswas, Akanksha Nagar & Stuti Mittal · Asian Journal of Medical Principles and Clinical Practice · 2026

Background: The increasing reliance on smartphones, laptops and desktop computers has increased prolonged screen exposure and sustained forward head posture among digital device users. Text Neck Syndrome (TNS) is commonly associated with neck pain, stiffness, muscular strain and...

Open access Research Article 10.9734/ajmpcp/2026/v9i2452

Annona muricata Ethanolic Leaf Extract Attenuates Dexamethasone Induced Oxidative Stress, Dyslipidemia and Hepatotoxicity in Rats through Upregulation of Endogenous Antioxidant Enzymes and Lipid Profile Normalization

Obi Ifeanyi Malachy, Chilaka Kingsley Chimsorom, Obi Helen Chinonyelum, Chilaka Jane Ugochinyere, Obi Frances Somtochukwu & Imolede Ohiomoje Isaac · Asian Journal of Medical Principles and Clinical Practice · 2026

Background: The therapeutic use of dexamethasone is often associated with adverse effects such as oxidative stress, dyslipidemia, and hepatotoxicity, primarily due to the generation of reactive oxygen species and disruption of metabolic homeostasis. Natural plant‑based antioxidan...

Open access Research Article 10.9734/ajmpcp/2026/v9i2450

Magnetic Resonance Imaging: Principles, Clinical Applications, and Problem Solving: A Critical Review

Fadhil Oufi Awad · Asian Journal of Medical Principles and Clinical Practice · 2026

Magnetic resonance imaging (MRI) has evolved over the past five decades from an experimental laboratory technique into one of the most versatile and clinically indispensable diagnostic imaging modalities in contemporary medicine. Grounded in the quantum mechanical phenomenon of n...

Open access Research Article 10.9734/ajmpcp/2026/v9i2449

The ‘Digital Phantom Limb’ Phenomenon and Bedside Clinical Competency among Nursing Students at Kaduna State College of Nursing Sciences, Kafanchan Campus: A Descriptive Study

Ali Babangida, Dogo Sholong Ayuba & Nicodemus Kutme Kutdang · Asian Journal of Medical Principles and Clinical Practice · 2026

Background: The pervasive integration of smartphones into nursing education has given rise to a phenomenon termed the “digital phantom limb”—a psychological and tactile dependence on the device characterised by phantom vibrations, compulsive checking urges, and separation anxiety...

Open access Research Article 10.9734/ajmpcp/2026/v9i2448