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All published articles 195

Acute Lymphocytic Leukaemic and Haemorrhagic Stroke in a 33-year-old Nigerian Man: A Case Report with a Rare Association and Treatment Challenges

Akpekpe Ebiwhiehi John, Ezunu Okechukwu Emmanuel, Nelson Elisha A, Yakub Yusuf, Okojie Promise Joseph, Akpekpe Joy, Ezunu Esther Ngozi & Alaba Luke Ayoade · Asian Journal of Research and Reports in Neurology · 2025

Intracerebral hemorrhage can be primary or secondary in origin. The secondary cause includes impairment of the coagulation process. Although acute lymphocytic leukemia (ALL) is a common childhood malignancy, it also occurs in adults. Even less frequently seen is the Chronic Lymph...

Open access Research Article 10.9734/ajorrin/2025/v8i1150

Association between Cardiac Troponin-I and Short-Term Outcomes in Subarachnoid Hemorrhage: A Prospective Observational Study

Md. Aminul Islam, Muhammad Robiul Hoque, Md. Mazharul Islam, Md Ashaduzzaman, Md. Hasan Ali, Kazi Irfan Subhan & Shuvro Saha · Asian Journal of Research and Reports in Neurology · 2025

Background: Subarachnoid hemorrhage (SAH) is a catastrophic neurological event, which is associated with significant medical complications. Cardiac troponin I(cTnI) release occurs frequently after SAH and has been associated with a neurogenic form of myocardial injury. The aim of...

Open access Research Article 10.9734/ajorrin/2025/v8i1151

Systemic Autoimmune Diseases with Neurological Manifestations: A Review of Lupus, Sarcoidosis and Vasculitis

Mohamed Abdirahman Abdi, Mary C. Joseph, Paul O. Etakewen, Enyichi L. Eke née Ugwulebo, Chigozie S. Ikeaba, Alaba L. Ayoade, Oluwafemi O. Akanbi & Damilare S. George · Asian Journal of Research and Reports in Neurology · 2025

Systemic autoimmune diseases represent a heterogeneous group of disorders characterised by immune-mediated inflammation that can affect multiple organ systems, including the nervous system. Among these, systemic lupus erythematosus (SLE), sarcoidosis, and systemic vasculitides st...

Open access Research Article 10.9734/ajorrin/2025/v8i1149

Should High Dose Corticosteroids be Abandoned in the Treatment of Post Traumatic Optic Neuropathy?: A Case Report

Lotfi Chaabani, Yosra Doulemi & Ksouri Saifeddine · Asian Journal of Research and Reports in Neurology · 2025

Aims: Post-traumatic optic neuropathy (TON) is an uncommon but potentially devastating complication of head trauma. Its management remains controversial, and the role of systemic corticosteroids is increasingly questioned. The aim of this report is to describe the clinical presen...

Open access Research Article 10.9734/ajorrin/2025/v8i1148

Thyroid Dysfunction and Its Neurological Indicators: A Review of Pathophysiology and Clinical Management

Tochukwu W. Okahia, Alaba L. Ayoade, Oluwafemi O. Akanbi, Oghenetega Arienmughare, Rachel Sophia Miller, Lordsfavour I. Anukam & Akeem Adeniyi Bakare · Asian Journal of Research and Reports in Neurology · 2025

Thyroid hormones play a pivotal role in neurodevelopment, neuroplasticity, and the regulation of central and peripheral nervous system functions. Consequently, disturbances in thyroid function can manifest with a broad spectrum of neurological symptoms, ranging from subtle cognit...

Open access Research Article 10.9734/ajorrin/2025/v8i1147

Hypertension and the Brain: Understanding the Mechanisms Linking Elevated Blood Pressure to Stroke, Small Vessel Disease and Cognitive Decline

Destiny C. Chinuokwu, Paul O. Etakewen, Theodora Chinecherem Okeke, Alaba L. Ayoade, Nkechi P. Ogwu, Oluwafemi O. Akanbi, Joan I. Joshua, Damilare S. George & Tochukwu W. Okahia · Asian Journal of Research and Reports in Neurology · 2025

Hypertension remains one of the most prevalent and modifiable risk factors for cerebrovascular diseases, contributing substantially to global morbidity and mortality. The persistent elevation of blood pressure initiates complex pathophysiological cascades that compromise vascular...

Open access Research Article 10.9734/ajorrin/2025/v8i1146

Metabolic Syndrome and the Brain: Neurological Sequelae of Insulin Resistance and Dyslipidemia

Treasure A. Chinuokwu, Destiny C. Chinuokwu, Alaba L. Ayoade & John A. Eze · Asian Journal of Research and Reports in Neurology · 2025

Metabolic syndrome is a complex clinical entity defined by a cluster of interconnected metabolic abnormalities, including central obesity, insulin resistance, hyperglycemia, hypertension, and dyslipidemia. Metabolic syndrome, characterised by the clustering of central obesity, in...

Open access Research Article 10.9734/ajorrin/2025/v8i1145

Smokeless Tobacco Induces Astrocyte Activation in The Hippocampus of Male Wistar Rat

Obot, Joseph Ime & Okoseimiema, Sonny Clement · Asian Journal of Research and Reports in Neurology · 2025

Smokeless tobacco has been used widely in our villages and rural communities, most especially to ease stress and improve the mood of the users. Its use has been established by literature to elicit several health outcomes. Despite the negative health effects associated with smokel...

Open access Research Article 10.9734/ajorrin/2025/v8i1144

Patterns and Predictors of Suicide Attempts Among Inpatients at the Federal Neuro-Psychiatric Hospital, Enugu, Nigeria: A Retrospective Cohort Study

Esther B. Adeniyi, Excel N. Victor-Anozie, Amarachi O. Ejindu, Chiemezie E. Ejiogu & Rukayat A. Ibrahim · Asian Journal of Research and Reports in Neurology · 2025

Background: Suicide is a significant public health concern, particularly among psychiatric patients. Understanding the patterns and predictors of suicide attempts within hospital settings is crucial for developing effective prevention strategies. Aim: This study aimed to identify...

Open access Research Article 10.9734/ajorrin/2025/v8i1142

Congenital Insensitivity to Pain in a Nigerian Child: A Case Report

Nneka Gabriel-Job, Chinwe Ogbonnaa-Njoku, Kelechi Cynthia Nwokoro, Chukwuemeka Nwuba & Nkechinyere Okoye · Asian Journal of Research and Reports in Neurology · 2025

Background: We present the case report of a Nigerian child with Congenital insensitivity to pain (CIP), a rare genetic neuropathy. This report presents the history, diagnosis and management of the child, highlighting the difficulties in diagnosing this condition, and emphasising...

Open access Research Article 10.9734/ajorrin/2025/v8i1143

Improved Cerebellar Structure and Neuronal Restoration by Combined Extracts of Ginger, Garlic, and Turmeric in Lead-Exposed Rats: A Histological and Morphometric Study

Cyril A. Agbor, Mfon Akpaso, Christabel O. Francis, Emmanuel I. Odom & Elton N. Takim · Asian Journal of Research and Reports in Neurology · 2025

Background: Heavy metal toxicity, particularly from lead exposure, poses significant neurodevelopmental risks, with the cerebellum being a key target. This study evaluated the ameliorative potential of a phytobiotic formulation comprising aqueous extracts of Zingiber officinale (...

Open access Research Article 10.9734/ajorrin/2025/v8i1141

Applying the M.O.T.I.V.E Framework to Support Conative Development in Educational Therapy for Children with Neurodevelopmental Disorders

Shania Saudah Yusof · Asian Journal of Research and Reports in Neurology · 2025

Children with neurodevelopmental disorders (NDDs) often face marked difficulties in initiating and sustaining purposeful, goal-directed behaviour. These difficulties are usually attributed to conative deficits—a critical domain of human development that governs motivation, voliti...

Open access Research Article 10.9734/ajorrin/2025/v8i1140

Neurohistochemistry and Immunological Assessment of Cerebellar-hippocampal Connectivity Following Artequin Exposure in Adult Wistar Rats

Nsikan-Abasi Bassey. Udoh, Kingsley Akaninyene Okon, Nathaniel Peter Udoakang & Moses Bassey Ekong · Asian Journal of Research and Reports in Neurology · 2025

Background and Aims: Artequin, a commonly used artemisinin-based antimalarial therapy, has been associated with central nervous system side effects, yet its effects on hippocampal–cerebellar function remain unclear. This study investigated it neurohistochemistry, immunoreactivity...

Open access Research Article 10.9734/ajorrin/2025/v8i1139

Brain Network Dysfunction and Rumination in Psychiatric Disorders: Integrative Insights into Educational Therapy as a Targeted Intervention

Meng Kiat Tan & Kok Hwee Chia · Asian Journal of Research and Reports in Neurology · 2025

Rumination, characterized by excessive repetitive and perseverative thinking about negative experiences and emotions, represents a transdiagnostic feature across multiple psychiatric disorders including major depressive disorder (MDD), anxiety disorders, post-traumatic stress dis...

Open access Research Article 10.9734/ajorrin/2025/v8i1138

Clueless Eyes in Intracranial Hypotension: A Case Report of Reverse INO

Deepinder Kaur Maini, Shashank Raj, Rajiv Anand, Varun Rehani, Nishant Tomar, Anubhav Gupta & Tanzeel Ahmad Wani · Asian Journal of Research and Reports in Neurology · 2025

Background: Internuclear ophthalmoplegia (INO) is generally caused by a lesion in the medial longitudinal fasciculus, characterised by diminished adduction and contralateral abduction nystagmus. Reverse INO, or "INO of abduction," is a rare variation, often linked to elevated int...

Open access Research Article 10.9734/ajorrin/2025/v8i1137