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All published articles 149

Assessment of the Outcomes of a Modified Version of the Reverse Hockey Stick Incision (mRHSI): A single Institutional Ambispective Longitudinal Study

Jitendra Kumar Nangal & K. S. Uthra · Asian Oncology Research Journal · 2026

Background: Neck dissection is a cornerstone of head and neck cancer management, requiring an incision design that balances surgical exposure with skin viability and cosmesis. Traditional designs, such as the Y-shaped incision, often suffer from poor blood supply at trifurcation...

Open access Research Article 10.9734/aorj/2026/v9i1135

Managing Persistent Cervical Aneurysmal Bone Cyst with Salvage Radiotherapy: A Case Report

Siddhartha Nanda, Amitima Mehta, Papuji Meher & Ashish Kumar Gupta · Asian Oncology Research Journal · 2026

Aims: Aneurysmal bone cyst (ABC) is a benign yet locally aggressive bone lesion that can lead to significant morbidity when it involves the spine. Cervical spine involvement is particularly rare and poses significant management challenges because of its proximity to the spinal co...

Open access Research Article 10.9734/aorj/2026/v9i1134

Institution-specific Validation of CTV-PTV Margins in Head and Neck Radiotherapy using Daily Cone Beam Computed Tomography on Halcyon Elite: A Population - Based Study

Jerin Josy & K. Yashmitha · Asian Oncology Research Journal · 2026

Aims: To quantitatively evaluate setup errors in head and neck cancer radiotherapy using Cone Beam Computed Tomography (CBCT) and determine whether the institutional Clinical Target Volume (CTV)–Planning Target Volume (PTV) margin adequately compensates for these uncertainties. S...

Open access Research Article 10.9734/aorj/2026/v9i1133

Survival and Prognostic Factors in Ewing Sarcoma: Evaluating the Role of Radiotherapy in Multimodality Management

Siddhartha Nanda, Amitima Mehta & Papuji Meher · Asian Oncology Research Journal · 2026

Background: Ewing sarcoma is an aggressive small round blue cell malignancy that predominantly affects children and young adults. Radiotherapy plays a central role in local control, particularly in anatomically complex or unresectable disease. Methods: A retrospective cohort stud...

Open access Research Article 10.9734/aorj/2026/v9i1132

Disparities in Targeted Therapy Access and Survival by Molecular Subtype in Breast Cancer: Evidence from Yemen

Gamal Abdul Hamid, Safa Shukry, Arig Shakeel & Amani Hussein · Asian Oncology Research Journal · 2026

Background: Breast cancer management has evolved toward precision medicine based on molecular subtypes. In low-resource settings like Yemen, access to targeted therapies is limited, potentially exacerbating survival disparities. This study examines treatment patterns and survival...

Open access Research Article 10.9734/aorj/2026/v9i1131

Integrative Structural and Network Analysis Identifies CDK9 as a Candidate Therapeutic Target in Short-Term Survivor High-Grade Serous Ovarian Cancer

S. R. Abhishek, R. M. Kavyashree, Krutika Arer, Suraj Manjunath Goudar, V. G. Shanmuga Priya & L. A. Ramachandra Prasad · Asian Oncology Research Journal · 2026

Background: High-grade serous ovarian cancer (HGSC) exhibits marked clinical heterogeneity, with Short-Term (ST) survivors demonstrating intrinsic resistance to standard chemotherapy and poor outcomes. Understanding tumor-intrinsic transcriptional vulnerabilities in ST-HGSC repre...

Open access Research Article 10.9734/aorj/2026/v9i1130

Oral Mucositis in Cancer Patients: Prevention and Treatment

Rokkam Vanya Sri, Harathi Kovvuri, J. Sunitha Blessy, Flowrence Evangelin Kona, M. John Winkle, Soujanya Ferdinand, B. Bhavani & K. Padmalatha · Asian Oncology Research Journal · 2026

Oral mucositis is a common and potentially severe complication of cancer therapy, particularly affecting high-risk populations such as pediatric patients, hematopoietic stem cell transplant recipients, and individuals with head and neck cancer. The incidence and severity of oral...

Open access Research Article 10.9734/aorj/2026/v9i1129

A Statistical Framework for Modelling Breast Cancer Disease Pathways with Multistate and Competing Risks Approaches

Francis Ayiah-Mensah, Emmanuel Ayitey, Vivian Nimoh, Mohammed Frempong & Frank Twenefour · Asian Oncology Research Journal · 2026

Background: Breast cancer is one of the leading causes of mortality in women in Ghana; prognostic studies are still dominated by single endpoint Kaplan-Meier and Cox models, which do not consider recurrence, progression, and competing mortality. The study aimed to come up with a...

Open access Research Article 10.9734/aorj/2026/v9i1128

Epigenetic Modifiers as Therapeutic Targets at the Interface of Infectious Diseases and Cancer Progression

Ogechi Cecilia Ofor, Joseph Adaviruku Sanni, Augusta Imomon, Juliana Ojonugwa Ocheni, Quadri O. Adewuyi, Ekaba Samson Gift, Sandra Ngozika Offor, Odeyemi Aduragbemi, Sonay Unsal, Yakubu Bitrus, Ijibadejo Margaret Seun & Possible Okikiola Popoola · Asian Oncology Research Journal · 2026

Epigenetic regulation plays a central role in controlling gene expression programs that govern cellular identity, immune responses, and adaptation to environmental stress. Increasing evidence demonstrates that dysregulation of epigenetic mechanisms is a shared hallmark of both in...

Open access Research Article 10.9734/aorj/2026/v9i1127

A Comprehensive Analysis of the Vascular Endothelial Growth Factor (VEGF) Family in Oral Carcinoma: From Molecular Mechanisms to Clinical Translation

Swarnava Chanda · Asian Oncology Research Journal · 2026

Oral squamous cell carcinoma has created a major health burden in developing countries. High incidence of tobacco addiction and limited awareness in the general population leads to its usual presentation in the advanced stage. Angiogenesis, being one of the important factors asso...

Open access Research Article 10.9734/aorj/2026/v9i1126

Precision Neuro-oncology: A Comprehensive Review of Molecular Diagnostics and Therapies in Glioma Care

Dhruva Trivedi, Richa Soni & Trupti Trivedi · Asian Oncology Research Journal · 2026

Cancer is the uncontrolled proliferation of abnormal cells that invades adjacent tissues and metastasizes in the lymphatic or bloodstream. Central Nervous System (CNS) tumors, and most notably gliomas are formidable to treat because of their aggressiveness, molecular heterogeneit...

Open access Research Article 10.9734/aorj/2026/v9i1125

Patterns of Peripheral Cytopenia in Hematological Malignancies: A Single-Center Retrospective Study from Aden, Yemen

Ghada Mohammed Abdulaziz & Gamal Abdul-Hamid · Asian Oncology Research Journal · 2026

Background: Peripheral cytopenias, including anemia, thrombocytopenia, bicytopenia, and pancytopenia, are common findings in patients with hematological malignancies (HMs) and often necessitate bone marrow evaluation for definitive diagnosis. This study aimed to determine the spe...

Open access Research Article 10.9734/aorj/2026/v9i1124

Advancements in Precision Medicine for Myelodysplastic Neoplasms and Acute Myeloid Leukemia: A Review on Genomics to Targeted Therapies

Eric Emmanuel U, Eberechukwu G C & Boloya V. E · Asian Oncology Research Journal · 2026

Myelodysplastic neoplasms (MDS) and acute myeloid leukemia (AML) are clonal hematopoietic disorders characterized by ineffective hematopoiesis and rapid proliferation of abnormal myeloid cells, respectively. Recent advances in molecular biology have significantly enhanced our und...

Open access Research Article 10.9734/aorj/2026/v9i1123

Unveiling the Awareness Gap: A Community-Based Cross-Sectional Study to Assess Knowledge and Attitude on Cervical Cancer among the Female Population

Mahima Prakash M D, Jennifer James, Sai Meenakshitha Panyala & Balaji Sathyanarayana Gupta · Asian Oncology Research Journal · 2026

Cervical cancer continues to be a significant public health issue in India, standing as the second most prevalent cancer among women. Despite being largely preventable through regular screening and human papillomavirus (HPV) vaccination, awareness remains inadequate and negative...

Open access Research Article 10.9734/aorj/2026/v9i1122

Unmasking Renal Cell Carcinoma: A Comprehensive Review of Histological Signatures and Subtypes

Alexander Obidike Naiho, Anthony Chibuzor Nnamudi, Clement Ndudi Isibor, Nicholas Asiwe, Emmanuel Onyebuchi Ezendiokwere, David Odah & Olisaemeka Ifechukwude Eboka · Asian Oncology Research Journal · 2026

Renal cell carcinoma (RCC) is the most common type of kidney cancer, accounting for over 90% of adult renal cancers. This review aimed to explore renal cell carcinomas, classifications and histological identifications. RCC is a diverse group of kidney tumors and accounts for most...

Open access Research Article 10.9734/aorj/2026/v9i1121